Oxepanes
Selleck Chemical LLC FHD-286-E1178-5MG
FHD-286 is a BRG1/BRM ATPase inhibitor for the treatment of BAF-related disorders such as acute myeloid leukemia
Selleck Chemical LLC BMS-502-E1896-1G
BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) and with IC50 values of 4 6 nM and 2 1 nM respectively BMS-502 also exhibits an EC50 value of 340 nM in the mouse cytotoxic T cell IFN- assay (mCTC) BMS-502 can be used in tumor immunity-related research
Medchemexpress LLC Epsilon-caprolactone | 502-44-3 | MFCD00003267 | 100.0% | 114.14 g/mol | C6H10O2 | 1 KG
Epsilon-caprolactone is a cyclic ester (lactone) monomer widely used in organic synthesis and polymer chemistry, notably for producing polycaprolactone via ring-opening polymerization. It is a colorless to light yellow liquid (C6H10O2, MW 114.14) with CAS 502-44-3 and is supplied at high purity for research and materials synthesis.
- Used as a monomer for ring-opening polymerization.
- Enables synthesis of biodegradable polycaprolactone.
- High purity suitable for research applications.
- Liquid at room temperature for easy handling.
- Reacts readily in nucleophilic ring-opening reactions.
Medchemexpress LLC Quercetin-3'-O-glucoside | 19254-30-9 | 464.38 | 5 MG
Quercetin-3'-O-glucoside is an orally active flavonoid glycoside with significant biological activities. It reduces liver glucose-6-phosphatase and regulates antioxidant enzyme activities. This compound inhibits DNA topoisomerase II and induces S-phase cell cycle arrest and apoptosis in hepatocellular carcinoma cells. It also inhibits EGFR-mediated signaling pathways and growth factor-induced migration in pancreatic cancer cells, alongside its free radical scavenging effects.
- Reduces liver glucose-6-phosphatase activity
- Regulates antioxidant enzyme activities
- Inhibits DNA topoisomerase II
- Induces S-phase cell cycle arrest and apoptosis in hepatocellular carcinoma cells
- Inhibits EGFR-mediated signaling pathways
- Exerts free radical scavenging effects
![eMolecules 7646-79-9 | Cobalt(II) chloride anhydrous | Oakwood Chemical | MFCD00010938 | 129.830 | Cl2Co | 97.000 | [Cl-].[Cl-].[Co++] | 1g | 698445932](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000163622.jpg-250.jpg)
eMolecules 7646-79-9 | Cobalt(II) chloride anhydrous | Oakwood Chemical | MFCD00010938 | 129.830 | Cl2Co | 97.000 | [Cl-].[Cl-].[Co++] | 1g | 698445932
Cobalt(II) chloride anhydrous | Oakwood Chemical | 7646-79-9 | MFCD00010938 | 129.830 | Cl2Co | 97.000 | [Cl-].[Cl-].[Co++] | 1g | 698445932
![eMolecules N-BOC-7-AZABICYCLO[4.1.0]HEPTANE | 153789-13-0 | MFCD16987842 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502182197.JPG-250.jpg)
eMolecules N-BOC-7-AZABICYCLO[4.1.0]HEPTANE | 153789-13-0 | MFCD16987842 | 1g
AstaTech | N-BOC-7-AZABICYCLO[4.1.0]HEPTANE | 1g | 273169483 | 74739 | 90.000 | 153789-13-0 | MFCD16987842 | 197.278 | C11H19NO2
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![eMolecules 498-07-7 | 1,6-Anhydro-b-D-glucopyranose | Chem-Impex | MFCD00063248 | 162.141 | C6H10O5 | 0.000 | O[C@@H]1[C@H]2CO[C@H](O2)[C@H](O)[C@H]1O | 25g | 112756506](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501715824.jpg-250.jpg)
eMolecules 498-07-7 | 1,6-Anhydro-b-D-glucopyranose | Chem-Impex | MFCD00063248 | 162.141 | C6H10O5 | 0.000 | O[C@@H]1[C@H]2CO[C@H](O2)[C@H](O)[C@H]1O | 25g | 112756506
1,6-Anhydro-b-D-glucopyranose | Chem-Impex | 498-07-7 | MFCD00063248 | 162.141 | C6H10O5 | 0.000 | O[C@@H]1[C@H]2CO[C@H](O2)[C@H](O)[C@H]1O | 25g | 112756506
Medchemexpress LLC D-glucitol, 2,5-anhydro-, 1,6-bis(dihydrogen phosphate) | 4429-47-4 | MFCD01863342 | 99.5% | 324.12 | C6H14O11P2 | 5 MG
2,5-Anhydro-D-glucitol-1,6-diphosphate is a research-grade biochemical reagent that acts as a limited stimulator of yeast pyruvate kinase and serves as an analogue of 2,5-anhydro-D-mannitol 1,6-bisphosphate. It is supplied as a colorless to light-yellow oil of high purity for enzymology and biochemical assays. This product is for research use only.
- Molecular formula C6H14O11P2; molecular weight 324.12
- CAS number 4429-47-4
- Purity 99.49%
- Appearance colorless to light yellow oil
- Storage: pure form -20°C (up to 3 years); in solvent -80°C (6 months), -20°C (1 month)
- Solubility details available on product datasheet
- Available in 5 mg pack
- Intended for research use only
Medchemexpress LLC Ethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enyl)acetate | 1166829-70-4 | MFCD18383324 | ≥97.0% | 294.19 g/mol | C16H27BO4 | 250 MG
Bpin-Cyclohexene-C-COOEt is a borylated cyclohexene ethyl ester used as a PROTAC linker and reagent in small-molecule synthesis. It has CAS number 1166829-70-4, molecular formula C16H27BO4, molecular weight 294.19 g/mol, and is supplied with ≥97.0% purity. It is commonly provided in small research pack sizes for laboratory synthesis.
- Borylated cyclohexene ethyl ester useful as a PROTAC linker.
- Documented for use in synthesis of SMARCA2/4 degrader compounds.
- High purity suitable for synthetic chemistry (≥97.0%).
- Available in small research pack sizes, including 250 MG.
- Contains a boronate (Bpin) functional group compatible with cross-coupling reactions.
Selleck Chemical LLC FHD-286-E1178-100MG
FHD-286 is a BRG1/BRM ATPase inhibitor for the treatment of BAF-related disorders such as acute myeloid leukemia
Medchemexpress LLC KCL-286 | 1952276-71-9 | 98.9% | 334.33 | 10 MG
KCL-286 | 1952276-71-9 | 98.9% | 334.33 | 10 MG
Medchemexpress LLC KCL-286 | 1952276-71-9 | 98.9% | 334.33 | 25 MG
KCL-286 is an orally active and brain-penetrant retinoic acid receptor (RAR) β2 agonist. It targets RARβ2 with selectivity over RAR α and RAR γ, activating RARβ2 in injured neurons. This compound induces axonal regeneration of both spinal and sensory nerves through the inhibitory environment of the CNS, modulates neuroinflammation, and extracellular matrix molecules.
- Orally active and brain-penetrant RAR β2 agonist
- Selectivity for RARβ2 over RAR α and RAR γ
- Activates RARβ2 in injured neurons
- Induces axonal regeneration of spinal and sensory nerves
- Modulates neuroinflammation and extracellular matrix molecules
- Can modulate CSPG expression by neuronal secretion of decorin to promote myelination and axonal growth
- Potential for research in spinal cord injury and traumatic nerve injury
Medchemexpress LLC β-D-glucopyranose 1-phosphate (disodium salt) | 83833-15-2 | 99.3% | 304.10 g·mol⁻¹ | C6H11Na2O9P | 5 MG
β-D-Glucopyranose 1-phosphate disodium salt is a biochemical reagent used in life-science research as a phosphorylated glucose intermediate. It is supplied as a white to off-white powder in small quantities for analytical and enzymology applications, and is accompanied by batch-specific quality documentation.
- High chemical purity suitable for analytical use.
- Molecular formula C6H11Na2O9P; molecular weight 304.10 g·mol⁻¹.
- Available in small pack sizes: 1 mg, 5 mg, 10 mg.
- Store sealed at -20°C, away from moisture and light; in solvent: -80°C (6 months), -20°C (1 month).
- Batch-specific certificate of analysis provided for purity verification.