Oxepanes
Medchemexpress LLC NCT-502 10mg | 1542213-00-2 | 395.45 g·mol⁻1 | C18H20F3N5S | 10 MG
NCT-502 is a small-molecule inhibitor of human phosphoglycerate dehydrogenase (PHGDH). It reduces glucose-derived serine production and is cytotoxic to PHGDH-dependent cancer cells, making it suitable for biochemical and cellular studies of serine biosynthesis and metabolic vulnerabilities in cancer research.
- PHGDH inhibitor (IC50 3.7 μM).
- High purity (~98.59%).
- Molecular weight 395.45 g·mol⁻1; formula C18H20F3N5S.
- Soluble in DMSO (~130 mg/mL); sonication recommended for dissolution.
- Stable when stored as powder at -20°C (up to 3 years) or 4°C (up to 2 years).
- Recommended frozen storage for solutions: -80°C (up to 2 years) or -20°C (up to 1 year).
Medchemexpress LLC Kaempferol-7-O-β-D-glucopyranoside | 16290-07-6 | 448.38 | 5 MG
Kaempferol-7-O-β-D-glucopyranoside is a flavonoid glycoside found in the root bark of *Cudrania tricuspidata*. It has demonstrated antioxidant activity by inhibiting Cu2+-induced lipid peroxidation of low-density lipoprotein and by scavenging DPPH free radicals.
- Inhibits lipid peroxidation.
- Possesses antioxidant properties.
- Scavenges free radicals.
TARGETMOL CHEMICALS INC FHD-286 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia. Purity 98.7%
Medchemexpress LLC β-D-Glucopyranose, 2-(acetylamino)-2-deoxy-, 1,3,4,6-tetraacetate | 7772-79-4 | ≥97.0% | 389.35 | 25 G
β-D-Glucopyranose, 2-(acetylamino)-2-deoxy-, 1,3,4,6-tetraacetate is a biochemical reagent used in glycobiology research. Glycobiology involves the study of the structure, synthesis, biology, and evolution of sugars, including carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is related to basic research, biomedicine, and biotechnology.
- Biochemical reagent for glycobiology research.
- Supports studies in carbohydrate chemistry and glycan enzymology.
- Useful for protein-glycan recognition research.
- Related to basic research, biomedicine, and biotechnology.
- Exhibits antiproliferative activity against DBA/2J mouse friend erythroleukemia cells with an IC50 of 400 μM.
Medchemexpress LLC Beta-D-Glucopyranose, 2-(acetylamino)-2-deoxy, 1,3,4,6-tetraacetate | 7772-79-4 | ≥97.0% | 389.35 | 50 G
Beta-D-Glucopyranose, 2-(acetylamino)-2-deoxy, 1,3,4,6-tetraacetate is a biochemical reagent utilized in glycobiology research, a field dedicated to studying the structure, synthesis, biology, and evolution of sugars. This encompasses carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the intricate role of glycans in biological systems. The compound appears as a white to off-white solid.
- Used in glycobiology research
- Appears as a white to off-white solid
- For research use only
- Has a purity of at least 97.0%
Selleck Chemical LLC BMS-502-E1896-100MG
BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) and with IC50 values of 4 6 nM and 2 1 nM respectively BMS-502 also exhibits an EC50 value of 340 nM in the mouse cytotoxic T cell IFN- assay (mCTC) BMS-502 can be used in tumor immunity-related research
Medchemexpress LLC NCT-502 100mg | 1542213-00-2 | 395.45 | C18H20F3N5S | 100 MG
NCT-502 is a small-molecule inhibitor of human phosphoglycerate dehydrogenase (PHGDH) supplied for research use. It is cytotoxic to PHGDH-dependent cancer cells and reduces glucose-derived serine production; reported IC50 against PHGDH is 3.7 μM. Molecular formula C18H20F3N5S, molecular weight 395.45 Da, reported purity 98.59%.
- Potent PHGDH inhibitor (IC50 ≈ 3.7 μM).
- Reduces glucose-derived serine production in cells.
- Reported high purity suitable for biochemical assays.
- Supplied as a 100 mg solid for laboratory research.
Medchemexpress LLC α-D-Glucopyranose (1,2,3,4,6-pentabenzoate) | 22415-91-4 | 98% | 700.69 | 5 G
α-D-Glucopyranose, 98% (1,2,3,4,6-Pentabenzoate, 98%) can be used in glycobiology research. It is for research use only and not sold to patients.
- Can be used in glycobiology research.
Chem-Impex International, Inc. 1,6-Anhydro-b-D-glucopyranose | MFCD00063248 | 25G
1,6-Anhydro-b-D-glucopyranose, MFCD00063248, 25G
Chem-Impex International, Inc. 1,6-Anhydro-b-D-glucopyranose | MFCD00063248 | 5G
1,6-Anhydro-b-D-glucopyranose, MFCD00063248, 5G
Medchemexpress LLC n-Octyl B-D-glucopyr 10mM 1mL | 29836-26-8 | 292.37 g/mol | C14H28O6 | 1 ML
n-Octyl β-D-glucopyranoside is a mild, non-ionic detergent used to solubilize membrane-bound proteins, prepare lipid vesicles, and aid membrane protein crystallization. It is supplied in solid and solution formats, including a ready-to-use 10 mM solution in DMSO (1 mL).
- Solubilizes membrane proteins while preserving native structure.
- Non-ionic, non-denaturing detergent suitable for protein reconstitution and crystallization.
- Available as 10 mM solution in DMSO (1 mL) or various solid weights for scale-up.
- Inhibits cavitation-induced cell lysis in vitro, aiding gentle sample handling.