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Oxepanes

Organic heterocyclic compounds that consist of a seven-membered ring in which one methylene group is replaced by oxygen.

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1

Medchemexpress LLC PAP 248-286 (acetate) | 98.9% | 4551.39 (free acid) | 1 MG
SDP

PAP 248-286 (Prostatic acid phosphatase (248-286)) acetate is a biologically active peptide that acts as a semen-derived enhancer of viral infection (SEVI) factor. This peptide significantly increases HIV infection by enhancing virion attachment to target cells.

  • Biologically active peptide
  • Semen-derived enhancer of viral infection (SEVI) factor
  • Significantly increases HIV infection by enhancing virion attachment to target cells
  • Applications in COVID-19 anti-virus research

ENCOMPASS_PREFERRED
2

Aobchem 4-(Ethoxycarbonyl)cyclohexene-1-boronic acid pinacol ester | ≥95% | CAS 1049004-32-1 | C15H25BO4 | 1g

4-(Ethoxycarbonyl)cyclohexene-1-boronic acid pinacol ester | ≥95% | CAS 1049004-32-1 | C15H25BO4 | 1g

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Benzoic acid, 4-[5-(4,7-dimethyl-2-benzofuranyl)-1,2,4-oxadiazol-3-yl]- | 1952276-71-9 | 98.9% | 334.33 | 50 MG
SDP

KCL-286 (C286) is an orally active and brain-penetrant retinoic acid receptor (RAR) β2 agonist (EC50 = 1.9 nM). It activates RARβ2 in injured neurons, inducing axonal regeneration and modulating neuroinflammation and extracellular matrix molecules. It can also modulate the expression of chondroitin sulfate proteoglycans (CSPGs) by neuronal secretion of decorin, promoting myelination and aiding axonal growth.

  • Targets RARβ2 with selectivity over RAR α and RAR γ.
  • Activates RARβ2 in injured neurons.
  • Induces axonal regeneration of spinal and sensory nerves.
  • Modulates neuroinflammation and extracellular matrix molecules.
  • Promotes myelination and aids axonal growth.
  • Suitable for research in spinal cord injury and traumatic nerve injury.

ENCOMPASS_PREFERRED
4

Medchemexpress LLC 4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-oxadiazol-3-yl)benzoic acid | 1952276-71-9 | 98.9% | 334.33 g·mol⁻1 | C19H14N2O4 | 5 MG
SDP

KCL-286 (C286) is a potent, selective retinoic acid receptor beta-2 (RARβ2) agonist reported to be orally active and brain-penetrant (reported EC50 = 1.9 nM). It is intended for research use in in vitro and in vivo studies of retinoid signaling and neurological pharmacology. Characterization includes molecular formula C19H14N2O4, molecular weight 334.33 g·mol⁻1, and CAS 1952276-71-9.

  • Potent RARβ2 agonist (EC50 = 1.9 nM).
  • Orally active and brain-penetrant in reported studies.
  • Suitable for in vitro and in vivo pharmacology studies.
  • Characterized by molecular formula C19H14N2O4 and molecular weight 334.33 g·mol⁻1.
  • Supplied as a high-purity research reagent (≈98.9% reported purity).

ENCOMPASS_PREFERRED
5

eMolecules​ 1061338-92-8 | (7-Oxa-bicyclo[4.1.0]hept-3-yl)-carbamic acid tert-butyl ester | J&W PharmLab LLC213.277 | C11H19NO3 | 96.000 | CC(C)(C)OC(=O)NC1CCC2OC2C1 | 1g | 599147849

(7-Oxa-bicyclo[4.1.0]hept-3-yl)-carbamic acid tert-butyl ester | J&W PharmLab LLC | 1061338-92-8213.277 | C11H19NO3 | 96.000 | CC(C)(C)OC(=O)NC1CCC2OC2C1 | 1g | 599147849

ENCOMPASS_PREFERRED
6

TARGETMOL CHEMICALS INC KCL-286 5MG

Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. KCL-286 is an orally available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI). Purity 99.93%

ENCOMPASS_PREFERRED
7

Medchemexpress LLC PAP 248-286 (acetate) | 98.9% | 4551.39 | 1 MG
SDP

PAP 248-286 (Prostatic acid phosphatase (248-286)) acetate is a biologically active peptide. It is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide significantly increases HIV infection by enhancing virion attachment to target cells.

  • Biologically active peptide
  • Semen-derived enhancer of viral infection (SEVI) factor
  • Enhances virion attachment to target cells, increasing HIV infection
  • Potential applications in COVID-19 anti-viral research

ENCOMPASS_PREFERRED
8

Medchemexpress LLC KCL-286 | 1952276-71-9 | 98.9% | 334.33 | 25 MG
SDP

KCL-286 is an orally active and brain-penetrant retinoic acid receptor (RAR) β2 agonist. It targets RARβ2 with selectivity over RAR α and RAR γ, activating RARβ2 in injured neurons. This compound induces axonal regeneration of both spinal and sensory nerves through the inhibitory environment of the CNS, modulates neuroinflammation, and extracellular matrix molecules.

  • Orally active and brain-penetrant RAR β2 agonist
  • Selectivity for RARβ2 over RAR α and RAR γ
  • Activates RARβ2 in injured neurons
  • Induces axonal regeneration of spinal and sensory nerves
  • Modulates neuroinflammation and extracellular matrix molecules
  • Can modulate CSPG expression by neuronal secretion of decorin to promote myelination and axonal growth
  • Potential for research in spinal cord injury and traumatic nerve injury

ENCOMPASS_PREFERRED