Oxolanes
Sigma Aldrich Fine Chemicals Biosciences 1,2:5,6-Di-O-isopropylidene-alpha-D-glucofuranose purum, >=98.0% (TLC) | 582-52-5 | MFCD00005544 | 25G
1,2:5,6-Di-O-isopropylidene-alpha-D-glucofuranose purum, >=98.0% (TLC) | Purity: >=98.0% (TLC) | Mol Wt: 260.28 | 582-52-5 | MFCD00005544 | 25G
Medchemexpress LLC Rk-582 | 2171388-28-4 | 98.05% | 510.60 | 25 MG
RK-582 is a tankyrase inhibitor and an orally bioavailable growth inhibitor, acting as an antitumor agent. It is suitable for research on colorectal cancer. This compound potently inhibits human tankyrase-1 and tankyrase-2 catalytic activity with high selectivity over PARP1, PARP2, and PARP10. It also inhibits Wnt/β-catenin signaling and the growth of COLO-320DM human colorectal cancer cells.
- Inhibits tankyrase-1 and tankyrase-2 catalytic activity
- Demonstrates high selectivity over PARP1, PARP2, and PARP10
- Inhibits Wnt/β-catenin signaling
- Potently inhibits the growth of COLO-320DM human colorectal cancer cells
- Modulates Wnt/β-catenin signaling by stabilizing AXIN2 and reducing active β-catenin
Sigma Aldrich Fine Chemicals Biosciences Sorbitan monostearate meets FCC analytical specifications | 1338-41-6 | 10KG
Sorbitan monostearate meets FCC analytical specifications | Mol Wt: 430.62 | 1338-41-6 | 10KG
Medchemexpress LLC KTX-582 intermediate-1 | 845508-29-4 | 326.41 g/mol | C16H22O5S | 10 MG
KTX-582 intermediate-1 is a synthetic chemical intermediate supplied for research use and intended for use in the synthesis of IRAK4-degrading compounds and antibody-drug conjugate preparation. The material is provided as a powder and requires controlled storage conditions for stability.
- used as a synthetic intermediate for research and development.
- intended for laboratory research use only; not for human or clinical applications.
- powder form with recommended storage conditions to preserve stability.
- supports synthetic workflows including ADC preparation and targeted degradation studies.
Medchemexpress LLC KTX-582 intermediate-1 | 845508-29-4 | 326.41 | C16H22O5S | 50 MG
KTX-582 intermediate-1 is a synthetic intermediate supplied for research use and intended for use in the synthesis of IRAK4 degrader compounds. It is suitable for laboratory-scale synthesis workflows and can be used in antibody-drug conjugate (ADC) preparation.
- Synthetic intermediate for small-molecule synthesis.
- Suitable for antibody-drug conjugate (ADC) preparation.
- Research use only; characterization data may be available from supplier.
- CAS number 845508-29-4 and molecular weight 326.41 g/mol.
- Store and handle according to supplier recommendations and applicable safety data sheets.
Apexbio Technology LLC Oligomycin Complex 1404-19-9 10mg
Oligomycin Complex is a mixture composed primarily of Oligomycin A B and C It functions as a mitochondrial ATP synthase inhibitor targeting specifically the F0 subunit to disrupt oxidative phosphorylation via inhibition of ATP generation Oligomycin A exhibits selective inhibition of ATP synthase with reported GI50 at approximately 270 nM By blocking mitochondrial ATP synthesis oligomycin promotes cellular metabolic shift from oxidative phosphorylation to glycolysis In cell culture studies using various cancer cell lines oligomycin treatment has been demonstrated to suppress mitochondrial respiration and can induce apoptosis Additionally oligomycin has been employed in research to examine cellular bioenergetics adaptations mitochondrial-related apoptosis pathways and synergy of chemotherapeutic combinations in vitro
Medchemexpress LLC KTX-582 intermediate-2 | 2434850-07-2 | 96.2% | 495.37 g·mol⁻¹ | C21H27BrN4O5 | 5 MG
KTX-582 intermediate-2 is a chemical intermediate used in the synthesis of IRAK4 degrader compounds and can be employed for antibody-drug conjugate (ADC) preparation. It is supplied as a solid with reported formula C21H27BrN4O5, molecular weight 495.37 g·mol⁻¹, and CAS number 2434850-07-2. Purity is batch-dependent and is provided on the supplier data sheet.
- Used as an intermediate in the synthesis of IRAK4 degrader compounds.
- Suitable for antibody-drug conjugate (ADC) preparation.
- Supplied in small-scale quantities suitable for research use.
- Reported molecular formula C21H27BrN4O5 and molecular weight 495.37 g·mol⁻¹.
- CAS number 2434850-07-2 for unambiguous identification.
Medchemexpress LLC Sorbitan trioleate 1kg
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD 200 mg/kg) Sorbitan trioleate can be used as an excipient such as surfactant emulsifier lubricant wetting agent dispersant thickener defoamer Pharmaceutical excipients or pharmaceutical auxiliaries refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations which can improve the stability solubility and processability of pharmaceutical preparations Pharmaceutical excipients also affect the absorption distribution metabolism and elimination (ADME) processes of co-administered drugs[1][2]
Chem-Impex International, Inc. 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-a-D-arabinofuranose | MFCD00083339 | 25G
2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-a-D-arabinofuranose, MFCD00083339, 25G
eMolecules Broadpharm (R)-tetrahydrofuran-3-amine 500mg 112545586 BP-11310 111769-26-7 MFCD08234424 87 122 C4H9NO
Broadpharm (R)-tetrahydrofuran-3-amine 500mg 112545586 BP-11310 111769-26-7 MFCD08234424 87 122 C4H9NO
Sigma Aldrich Fine Chemicals Biosciences Sorbitan monostearate meets FCC analytical specifications | 1338-41-6 |
Sorbitan monostearate meets FCC analytical specifications | Mol Wt: 430.62 | 1338-41-6 |
Medchemexpress LLC Sorbitan monooctadecanoate | 1338-41-6 | MFCD00005366 | 95.0% | 430.6 g/mol | C24H46O6 | 500 G
Sorbitan monooctadecanoate is a hydrophobic, nonionic surfactant used as a pharmaceutical excipient to stabilize, solubilize, and improve processing of formulations. It is a white to off-white solid commonly employed in emulsions, suspensions, and wetting systems.
- Functions as an emulsifier and nonionic surfactant.
- Improves solubility and dispersion of hydrophobic ingredients.
- Acts as a wetting and suspending agent in formulations.
- Solid, easy-to-handle form suitable for a range of processing methods.
- Stable under normal ambient storage for typical shelf life.
Medchemexpress LLC Sorbitan monooctadecanoate | 1338-41-6 | MFCD00005366 | 95.0% | 430.6 g/mol | C24H46O6 | 1 KG
Sorbitan monooctadecanoate is a nonionic surfactant and emulsifying excipient used to stabilize oil-water systems and improve dispersion of lipophilic compounds in formulations. It is commonly applied as an emulsifier, solubilizer, wetting agent, and dispersant in laboratory and formulation settings.
- Acts as a nonionic emulsifier for oil-in-water systems.
- Improves solubility of lipophilic compounds.
- Provides wetting and dispersing action for suspensions.
- Compatible with a wide range of formulation matrices.
- Available in multiple pack sizes for laboratory use.
Medchemexpress LLC Ktx-582 intermediate-1 | 845508-29-4 | 326.41 | C16H22O5S | 25 MG
KTX-582 intermediate-1 is an organic synthesis intermediate used in the preparation of the IRAK4 degrader KTX-582. It is supplied for research use and is characterized by its chemical identifiers and formula.
- Used as an intermediate in small-molecule synthesis
- Cas number 845508-29-4
- Molecular formula C16H22O5S
- Molecular weight 326.41
- Intended for research use only
- Pack size commonly 25 mg
Medchemexpress LLC Diacetone-β-D-fructose | 20880-92-6 | 98.0% | 260.28 | 500 G
Diacetone-β-D-fructose is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is intended for research use only.
- Biochemical reagent
- Can be used as a biological material
- Can be used as an organic compound for life science related research