Oxolanes
Chem-Impex International, Inc. Sorbitan monostearate | MFCD00005366 | 1KG
Sorbitan monostearate, MFCD00005366, 1KG
eMolecules 13774-81-7 | Borane Ammonia Complex | Accela ChemBio (ASD) | MFCD00075639 | 30.870 | BH6N | 98.000 | B.N | 5g | 736385746
Borane Ammonia Complex | Accela ChemBio (ASD) | 13774-81-7 | MFCD00075639 | 30.870 | BH6N | 98.000 | B.N | 5g | 736385746
Medchemexpress LLC Moenomycin complex | 11015-37-5 | 99.9% | 10 MG
Moenomycin complex is a class of antibacterial agents and PBP inhibitors, effective against various bacterial PBPs. It functions by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs), inhibiting bacterial growth. This product is intended for research use in bacterial infections.
- Appearance: Solid
- Color: Off-white to light yellow
- Solubility (in vitro): Ethanol : 25 mg/mL (requires ultrasonic and warming)
- Storage: Powder at -20°C for 3 years; in solvent at -80°C for 6 months, -20°C for 1 month
- Shipping: Room temperature in continental US; may vary elsewhere
Apexbio Technology LLC Oligomycin Complex 1404-19-9 10mg
Oligomycin Complex is a mixture composed primarily of Oligomycin A B and C It functions as a mitochondrial ATP synthase inhibitor targeting specifically the F0 subunit to disrupt oxidative phosphorylation via inhibition of ATP generation Oligomycin A exhibits selective inhibition of ATP synthase with reported GI50 at approximately 270 nM By blocking mitochondrial ATP synthesis oligomycin promotes cellular metabolic shift from oxidative phosphorylation to glycolysis In cell culture studies using various cancer cell lines oligomycin treatment has been demonstrated to suppress mitochondrial respiration and can induce apoptosis Additionally oligomycin has been employed in research to examine cellular bioenergetics adaptations mitochondrial-related apoptosis pathways and synergy of chemotherapeutic combinations in vitro
Medchemexpress LLC KTX-582 intermediate-2 | 2434850-07-2 | 96.2% | 495.37 g·mol⁻¹ | C21H27BrN4O5 | 5 MG
KTX-582 intermediate-2 is a chemical intermediate used in the synthesis of IRAK4 degrader compounds and can be employed for antibody-drug conjugate (ADC) preparation. It is supplied as a solid with reported formula C21H27BrN4O5, molecular weight 495.37 g·mol⁻¹, and CAS number 2434850-07-2. Purity is batch-dependent and is provided on the supplier data sheet.
- Used as an intermediate in the synthesis of IRAK4 degrader compounds.
- Suitable for antibody-drug conjugate (ADC) preparation.
- Supplied in small-scale quantities suitable for research use.
- Reported molecular formula C21H27BrN4O5 and molecular weight 495.37 g·mol⁻¹.
- CAS number 2434850-07-2 for unambiguous identification.
Medchemexpress LLC Spiroindoline-based tankyrase inhibitor | 2171388-28-4 | 98.1% | C27H35FN6O3 | 10MG
RK-582 is an orally active, spiroindoline-based selective tankyrase inhibitor with nanomolar potency and demonstrated antiproliferative activity in colorectal cancer models.
Medchemexpress LLC Diacetone-β-D-fructose | 20880-92-6 | 98.0% | 260.28 | 500 G
Diacetone-β-D-fructose is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is intended for research use only.
- Biochemical reagent
- Can be used as a biological material
- Can be used as an organic compound for life science related research
Sigma Aldrich Fine Chemicals Biosciences VHL Protein Complex Active
The VHL complex is a multi-subunit ubiquitin ligase composed of VHL, Elongin B, Elongin C, Cul2 and Rbx1. The VHL protein serves as the substrate recognition component and is linked by Elongin C to a heterodimeric Cul2/Rbx1 module that functions as a potent activator of the ubiquitination of target proteins by an E2 conjugating enzyme. Elongin B interacts with the complex through Elongin C and appears to stabilize the binding of Elongin C to VHL. The primary function of the VHL complex is to regulate HIF (hypoxia inducible factor) activity by targeting the hydroxylated HIF-1alpha subunit for ubiquitination and rapid proteasomal degradation under normoxic conditions. It therefore plays an important role in the regulation of hypoxia-inducible genes such as the vascular endothelial growth factor (VEGF) and glucose transport-1 (Glut-1). Mutations in VHL are associated with the inherited von Hippel-Lindau (VHL) cancer syndrome and numerous forms of renal cell carcinoma.
