Mirtazapine is a small-molecule antagonist targeting central presynaptic 2-adrenergic receptors as well as serotonin 5-HT2 and 5-HT3 receptors and central histamine H1 receptors It is designed to modulate monoaminergic neurotransmission thereby affecting mood regulation pathways Mirtazapine exerts its biological activity primarily through selective antagonism of central presynaptic 2-adrenergic receptors inducing increased synaptic release of norepinephrine and serotonin It also antagonizes serotonin 5-HT2 and 5-HT3 receptors Based on these pharmacological properties mirtazapine holds research potential in the fields of neuroscience and psychopharmacology particularly for studies involving depressive disorders anxiety conditions and mood regulation