Piperazinoazepines
Mirtazapine, 98%
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.35 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mirtazapine 98.0+%, TCI America™
CAS: 85650-52-8 Molecular Formula: C17H19N3 Molecular Weight (g/mol): 265.36 MDL Number: MFCD00865427 InChI Key: RONZAEMNMFQXRA-UHFFFAOYSA-N Synonym: mirtazapine,remeron,mepirzepine,remergil,zispin,remergon,rexer,6-azamianserin,remeron soltab,mepirzapin PubChem CID: 4205 ChEBI: CHEBI:6950 SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Mianserin Hydrochloride 98.0+%, TCI America™
CAS: 21535-47-7 Molecular Formula: C18H21ClN2 Molecular Weight (g/mol): 300.83 MDL Number: MFCD00055072 InChI Key: YNPFMWCWRVTGKJ-UHFFFAOYNA-N Synonym: mianserin hydrochloride,mianserine hydrochloride,mianserin hcl,athymil,bolvidon,tolvon,tolvin,org gb 94,lerivon PubChem CID: 68551 ChEBI: CHEBI:31843 IUPAC Name: hydrogen 5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene chloride SMILES: [H+].[Cl-].CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 1 ML
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist. Mirtazapine enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors
- Blocks 5-HT2 and 5-HT3 receptors
- Enhances norepinephrine release
- Enhances 5-HT1A-mediated serotonergic transmission
- Reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes
- Inhibits hepatic macrophage/monocyte activation and decreases pro-inflammatory cytokine and chemokine production
Medchemexpress LLC Mirtazapine-d3 | 1216678-68-0 | 99.7% | 1 MG
Mirtazapine-d3 is a deuterium labeled Mirtazapine, a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It functions by blocking 5-HT2 and 5-HT3 receptors. This compound is for research use only and can be utilized as a tracer or an internal standard for quantitative analysis.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits 5-HT2 receptors
- Inhibits 5-HT3 receptors
- Deuterium labeled compound
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 1 G
Mianserin hydrochloride is an orally active H1 receptor antagonist that can activate κ-opioid and octapamine receptors. It increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation. This compound modulates social and exploratory behaviour, raises electroconvulsive thresholds, and can be used for research of neurological diseases, including depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid and octapamine receptors
- Increases ERK1/2 and CREB phosphorylation
- Antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation
- Modulates social and exploratory behaviour
- Raises electroconvulsive thresholds
- Used for research of neurological diseases, such as depression and epilepsy
Medchemexpress LLC Mianserin hydrochloride | 21535-47-7 | 99.95% | 1 ML
Mianserin hydrochloride is an orally active H1 receptor antagonist that can also activate κ-opioid and octapamine receptors. It increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and dynorphin A-induced MAPK phosphorylation. This compound modulates social and exploratory behavior, raises electroconvulsive thresholds, and is used in research for neurological diseases like depression and epilepsy.
- Orally active H1 receptor antagonist
- Activates κ-opioid receptor and octopamine receptor
- Increases ERK1/2 and CREB phosphorylation
- Antagonizes κ-opioid agonist and dynorphin A-induced MAPK phosphorylation
- Modulates social and exploratory behavior
- Raises electroconvulsive thresholds
- Used for research of neurological diseases, including depression and epilepsy
TARGETMOL CHEMICALS INC R-Mirtazapine 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. (R)-Mirtazapine ((R)-Org3770) is the R(-)-enantiomer of Mirtazapine, exhibiting anti-injury sensory properties in an animal model of acute thermal hyperalgesia. It functions as a 5-HT3 receptor antagonist and serves as a potential analgesic. Purity 99.75%
TARGETMOL CHEMICALS INC MIRTAZAPINE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury. purity: 99%
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 265.36 | C17H19N3 | 10 MG
Mirtazapine analytical reference standard for research and analytical applications, provided as a small-mass powdered material suitable for preparing stock solutions and calibrants. It represents the standard form of mirtazapine used in method development, calibration, and quality control workflows.
- Analytical reference suitable for method development and calibration.
- Used in studies targeting 5-HT, histamine H1, and adrenergic receptors.
- Molecular formula C17H19N3 and molecular weight 265.36 g/mol.
- Available in small mass packs (for example, 1 mg, 5 mg, 10 mg) for stock preparation.
- Storage guidance provided for powder and solutions to preserve stability.
Medchemexpress LLC S-mirtazapine | 61337-87-9 | MFCD00006761 | 99.8% | 265.35 g/mol | C17H19N3 | 10 MG
(S)-Mirtazapine is the S(+)-enantiomer of mirtazapine, provided as a solid research chemical for laboratory and analytical use. For research use only; not for human or clinical use.
- High purity: 99.76% (enantiomeric excess 98.35%).
- Chemical formula: C17H19N3; molecular weight: 265.35 g/mol.
- Appearance: off-white to light yellow powder.
- Solubility: ≥100 mg/mL in DMSO; use newly opened DMSO due to hygroscopicity.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Pack sizes suitable for small-scale research, including 10 mg quantities.
Medchemexpress LLC Mirtazapine | 85650-52-8 | 99.9% | 50 MG
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as a 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor antagonist.
- Potent and orally active noradrenergic and specific serotonergic antidepressant.
- Antagonizes adrenergic α2-autoreceptors and α2-heteroreceptors, and blocks 5-HT2 and 5-HT3 receptors.
- Enhances the release of norepinephrine and 5-HT1A-mediated serotonergic transmission.
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro.
- Inhibits hepatic innate immune networks to attenuate immune-mediated liver injury in mice in vivo.
- Suppresses Con A-induced increases in hepatic ICAM-1 expression, reducing neutrophil recruitment into the liver.
Medchemexpress LLC Mirtazapine | 85650-52-8 | MFCD00865427 | 99.9% | 25 MG
Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. It acts as an antagonist for 5-HT2, 5-HT3, histamine H1 receptors, and α2-adrenoceptors. This compound is intended for research use only and is not sold to patients.
- Potent and orally active NaSSA agent
- Antagonist of multiple receptors: 5-HT2, 5-HT3, histamine H1 receptor, and α2-adrenoceptor
- Enhances norepinephrine and 5-HT1A-mediated serotonergic transmission
- Inhibits hepatic macrophage/monocyte activation, decreases pro-inflammatory cytokine and chemokine production, and suppresses ICAM-1 expression, leading to reduced neutrophil recruitment into the liver (observed in mice)
- Metabolized by CYP1A2, CYP2D6, and CYP3A4 isoenzymes
- Significantly reduces activation-induced release of cytokine/chemokine mediators from human CD14+ monocytes in vitro