Piperidines
Aobchem Methanone (3-chlorophenyl)(2 6-difluorophenyl)- | 95% | CAS 1332354-47-8 | C13H7ClF2O | 500mg
Methanone (3-chlorophenyl)(2 6-difluorophenyl)- | 95% | CAS 1332354-47-8 | C13H7ClF2O | 500mg
Medchemexpress LLC Avibactam impurity 1 | 400626-71-3 | MFCD14635665 | 5g
Avibactam impurity 1 is an impurity of Avibactam (HY-14879)
Medchemexpress LLC Avibactam sodium (standard) | 1192491-61-4 | 99.9% | 287.23 | 50 MG
Avibactam (sodium) (Standard) is the analytical standard of Avibactam (sodium). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.
- Grade of analytical standard
- Reference standard supplied assay
- Commonly used in qualitative research experiments in HPLC, GC and MS
- Commonly used in quantitative research experiments in HPLC, GC and MS
- Commonly used in methodological research experiments in HPLC, GC and MS
Medchemexpress LLC HY-123937 5mg Medchemexpress, THAL-SNS-032 CAS:2139287-33-3 Purity:>98%
Medchemexpress, HY-123937 5mg THAL-SNS-032 CAS:2139287-33-3 THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN) [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Cabergoline United States Pharmacopeia (USP) Reference Standard | 81409-90-7 | MFCD00867887 | 125MG
Cabergoline United States Pharmacopeia (USP) Reference Standard | Mol Wt: 451.6 | 81409-90-7 | MFCD00867887 | 125MG
![Medchemexpress LLC 1-[3-(2,3-dichlorophenyl)-2H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methylpiperidin-4-amine | 2160546-07-4 | 100.0% | C17H18Cl2N6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261615.png-250.jpg)
Medchemexpress LLC 1-[3-(2,3-dichlorophenyl)-2H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methylpiperidin-4-amine | 2160546-07-4 | 100.0% | C17H18Cl2N6 | 10MG
IACS-13909 is a selective, potent, orally active allosteric inhibitor of SHP2 (PTPN11) used as a research compound to probe MAPK pathway signaling and antitumor activity in RTK-dependent models. It provides defined potency, high supplied purity, and solubility/formulation data to support in vitro and in vivo pharmacology studies.
- Selective SHP2 allosteric inhibitor with IC50 15.7 nM and Kd 32 nM.
- High supplied purity (99.97%) suitable for biological assays.
- Soluble in DMSO at 10 mg/mL for in vitro use, with in vivo formulation options.
- Available in multiple solid and solution pack sizes for flexible dosing.
- Applicable to cellular and preclinical pharmacology studies of MAPK pathway signaling.
Medchemexpress LLC Nelfinavir mesylate | 159989-65-8 | C33H49N3O7S2 | 25 MG
Nelfinavir Mesylate, also known as AG 1343 Mesylate, is a potent and orally bioavailable HIV-1 protease inhibitor. It is also described as a broad-spectrum anticancer agent and an inhibitor of SARS-CoV 3CLpro.
- Potent HIV-1 protease inhibitor (Ki=2 nM)
- Inhibits proliferation of multiple myeloma cells (IC50 of 1-5 μM)
- Triggers apoptosis of myeloma cell lines
- Decreases phosphorylation of AKT, STAT-3, ERK1/2
- Activates the pro-apoptotic pathway of the unfolded protein response system
- Inhibits SARS-CoV 3CLpro (IC50 of 35.93 μM)
- Decreases multiple myeloma cell growth in animal models
Medchemexpress LLC Ropivacaine | 84057-95-4 | MFCD00078774 | 100.0% | 50 MG
Overview of Ropivacaine
Ropivacaine is a potent sodium channel blocker. It works by blocking impulse conduction through reversible inhibition of sodium ion influx in nerve fibers. Additionally, Ropivacaine acts as an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. It is utilized in the research of neuropathic pain management.
Features and Benefits
- Potent sodium channel blocker.
- Blocks impulse conduction by inhibiting sodium ion influx.
- Inhibits K2P TREK-1 (IC50 of 402.7 μM).
- Used for neuropathic pain management research.
- Epidural administration blocks neuropathic pain and delays its development.
- Inhibits pressure-induced increases in filtration coefficient.
- Prevents pressure-induced lung edema and hyperpermeability.
- Inhibits pressure-induced NO production.
eMolecules 854056-07-8 | Medchem Express | Ropivacaine (mesylate) | 10mg | 527573892 | HY-B0563C | MFCD08458442 | 370.51 | C18H30N2O4S
Medchem Express | Ropivacaine (mesylate) | 10mg | 527573892 | HY-B0563C | 854056-07-8 | MFCD08458442 | 370.510 | C18H30N2O4S
Medchemexpress LLC 1,2-pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-(phenylmethyl) ester, (2R)- | 400626-71-3 | MFCD14635665 | 10g
Avibactam impurity 1 is an impurity of Avibactam (HY-14879)
eMolecules 1373765-19-5 | Medchem Express | IPSU | 5mg | 446263520 | HY-13796 | MFCD25976654 | 405.502 | C23H27N5O2
Ambeed | 6-Fluorobenzo[c][12]oxaborol-1(3H)-ol | 100mg | 600844860 | A647056 | 174671-89-7 | MFCD10699481 | 151.930 | C7H6BFO2
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Medchemexpress LLC Levobupivacaine hydrochloride | 27262-48-2 | >99.8% | 5 MG
Levobupivacaine hydrochloride is a long-acting amide local agent that can suppress or relieve pain. It exerts analgesic effects through reversible blockade of neuronal sodium channels. It can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. It is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo and can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer.
- Long-acting amide local agent
- Suppresses or relieves pain
- Exerts analgesic effects through reversible blockade of neuronal sodium channels
- Inhibits impulse transmission and conduction in cardiovascular and other tissues
- Metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo
- Induces ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer
Medchemexpress LLC HY-14879B 200mg , Avibactam (sodium hydrate) CAS: Purity:98%
Medchemexpress, HY-14879B 200mg Avibactam (sodium hydrate) CAS: Formula:C7H12N3NaO7S IC50: 8 nM (TEM-1), 5 nM (CTX-M-15) Purity:98% Avibactam sodium hydrate is a covalent, reversible β-lactamase inhibitor, inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 of 8 nM and 5 nM, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Accela Chembio Inc 1 | 1'-(azodicarbonyl)dipiperidine (addp) | 5g | 10465-81-3 | MFCD00010111 | 98% | Shelf Life: 1260 Days | +4
1 | 1'-(azodicarbonyl)dipiperidine (addp) | 5g | 10465-81-3 | MFCD00010111 | 98% | Shelf Life: 1260 Days | +4
![eMolecules 27262-47-1 | LEVOBUPIVACAINE | AstaTech | MFCD00936851 | 288.435 | C18H28N2O | 95.000 | CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C | 0.25g | 796988911](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502456373.PNG-250.jpg)
eMolecules 27262-47-1 | LEVOBUPIVACAINE | AstaTech | MFCD00936851 | 288.435 | C18H28N2O | 95.000 | CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C | 0.25g | 796988911
LEVOBUPIVACAINE | AstaTech | 27262-47-1 | MFCD00936851 | 288.435 | C18H28N2O | 95.000 | CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C | 0.25g | 796988911