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Filtered Search Results
eMolecules 1-BOC-PIPERIDINE-3-BORONIC 1G
5000158467 1-BOC-PIPERIDINE-3-BORONIC 1G
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eMolecules 3-BROMO-4-OXO-PIPERIDINE-1- 5G
5000216688 3-BROMO-4-OXO-PIPERIDINE-1- 5G
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Medchemexpress LLC Dimethyl fumarate | 624-49-7 | 100.0% | 144.13 | 25 MG
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Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator that induces upregulation of antioxidant gene expression. It induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research. It also acts as an immune modulator and inducer of the antioxidant response, suppressing HIV replication and neurotoxin release.
- Orally active and brain-penetrant Nrf2 activator
- Induces upregulation of antioxidant gene expression
- Induces necroptosis in colon cancer cells
- Induces cell autophagy
- Used for multiple sclerosis research
- Immune modulator
- Inducer of the antioxidant response
- Suppresses HIV replication and neurotoxin release
- Inhibits dendritic cell (DC) maturation
- Impairs NF-κB signaling
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Medchemexpress LLC Piperine | 94-62-2 | 99.0% | 285.34 | 10 MM * 1 ML
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Piperine is an alkaloid isolated from pepper, which inhibits the activity of P-glycoprotein and CYP3A4. It has demonstrated in vitro cytotoxic activity and immunomodulatory, anti-oxidant, anti-asthmatic, anti-carcinogenic, anti-inflammatory, anti-ulcer, and anti-amoebic properties. It can enhance the bioavailability of other drugs.
- Inhibits activity of P-glycoprotein and CYP3A4
- Exhibits in vitro cytotoxic activity
- Possesses immunomodulatory, anti-oxidant, anti-asthmatic, anti-carcinogenic, anti-inflammatory, anti-ulcer, and anti-amoebic properties
- Enhances bioavailability of other drugs
- Inhibits phosphorylation of I-κB, p65, p38, ERK, and JNK
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382090 AUTOTAXIN-IN-3 50MG
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Apexbio Technology LLC Anamorelin 249921-19-5 10mg
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Anamorelin (CAS 249921-19-5) is a synthetic small-molecule agonist of the growth hormone secretagogue receptor (GHSR) By binding to and activating GHSR centrally Anamorelin replicates the orexigenic and anabolic effects of endogenous ghrelin promoting appetite stimulation and growth hormone release This mechanism may also contribute to modulation of inflammatory pathways as GHSR activation is associated with reduced production of pro-inflammatory cytokines such as TNF-alpha and interleukin-6 Anamorelin is primarily investigated for its potential in studies of cancer cachexia appetite regulation and metabolic research
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Accela Chembio Inc N-boc-2-piperidinemethanol | 25g | 157634-00-9 | MFCD04114966 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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N-boc-2-piperidinemethanol | 25g | 157634-00-9 | MFCD04114966 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Selleck Chemical LLC Revefenacin S5258-2mg
Revefenacin (TD-4208 GSK-1160724) is a potent lung-selective long-acting muscarinic antagonist that may be for the treatment of respiratory disease
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Apexbio Technology LLC Pirenzepine dihydrochloride 29868-97-1 100mg
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Pirenzepine dihydrochloride (CAS 29868-97-1) is a selective antagonist of the muscarinic acetylcholine M1 receptor By inhibiting M1 receptor-mediated signaling it effectively suppresses gastric acid secretion and alleviates smooth muscle contractions These properties have supported its use in studies related to peptic ulcer disease where modulation of gastric secretory activity is relevant Additionally pirenzepine dihydrochloride has been investigated for its capacity to inhibit cancer cell proliferation making it valuable for research into tumor biology and potential therapeutic strategies targeting the cholinergic system
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Pfaltz & Bauer PIPERINE 97% 5G
Piperine 97%; 5G CAS# 94-62-2
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![eMolecules Medchem Express / FGTI-2734 (mesylate) / 5mg / 515744047 / HY-128350A / / 2702297-24-1 / [null] / 606.730 / C27H35FN6O5S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502462872.JPG-250.jpg)
eMolecules Medchem Express / FGTI-2734 (mesylate) / 5mg / 515744047 / HY-128350A / / 2702297-24-1 / [null] / 606.730 / C27H35FN6O5S2
Medchem Express / FGTI-2734 (mesylate) / 5mg / 515744047 / HY-128350A / / 2702297-24-1 / [null] / 606.730 / C27H35FN6O5S2
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eMolecules ChemScene / 4-Oxopiperidine-1-carbonitrile / 100mg / 788448714 / CS-0609486 / 0.000 / 1642156-93-1 / MFCD20258775 / 124.143 / C6H8N2O
ChemScene / 4-Oxopiperidine-1-carbonitrile / 100mg / 788448714 / CS-0609486 / 0.000 / 1642156-93-1 / MFCD20258775 / 124.143 / C6H8N2O
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![eMolecules TERT-BUTYL 2-OXA-5,8-DIAZASPIRO[3.5]NONANE-5-CARBOXYLATE | 1367936-05-7 | MFCD22035556 | 0.1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502181596.JPG-250.jpg)
eMolecules TERT-BUTYL 2-OXA-5,8-DIAZASPIRO[3.5]NONANE-5-CARBOXYLATE | 1367936-05-7 | MFCD22035556 | 0.1g
AstaTech | TERT-BUTYL 2-OXA-5,8-DIAZASPIRO[3.5]NONANE-5-CARBOXYLATE | 0.1g | 571075362 | P20547 | 95.000 | 1367936-05-7 | MFCD22035556 | 228.292 | C11H20N2O3
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Medchemexpress LLC Pomalidomide-C12-NH2 hydrochloride | 2862774-02-3 | 97.1% | 493.04 g/mol | C25H37ClN4O4 | 5 MG
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Pomalidomide-C12-NH2 hydrochloride is an E3 ligase ligand-linker conjugate used as the Cereblon-directed ligand component in PROTAC design targeting KRAS G12C. Supplied as the hydrochloride salt for research use, it is provided as a solid in milligram scales and is characterized by high purity and defined storage recommendations.
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Selleck Chemical LLC Niraparib tosylate
Niraparib tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3 8 nM/2 1 nM Niraparib increases formation of PARP-DNA complexes resulting in DNA damage apoptosis and cell death
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