Piperidines
Sigma Aldrich Fine Chemicals Biosciences Paroxetine hydrochloride hemihydrate >=98% (HPLC), powder | 110429-35-1 | MFCD03658863 | 50MG
Paroxetine hydrochloride hemihydrate >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 374.83 | 110429-35-1 | MFCD03658863 | 50MG
Enzo Life Sciences Ceritinib (free base) (500mg). CAS: 1032900-25-6
Ceritinib is a selective inhibitor of ALK, a target found in metastatic non-small cell lung cancer. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
eMolecules 170098-38-1 | Medchem Express | Alvimopan (dihydrate) | 5mg | 446271508 | HY-76657A | MFCD00927248 | 460.571 | C25H36N2O6
Ambeed | 1-Propyl-1234-tetrahydropyrimidine-24-dione | 100mg | 714081784 | A1127570 | 24466-52-2 | MFCD00466422 | 154.169 | C7H10N2O2
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![Medchemexpress LLC 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol | 371935-74-9 | MFCD11983145 | 99.0% | 348.36 g/mol | C19H16N4O3 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213142.png-250.jpg)
Medchemexpress LLC 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol | 371935-74-9 | MFCD11983145 | 99.0% | 348.36 g/mol | C19H16N4O3 | 50 MG
A small-molecule research reagent that potently inhibits PI3K and mTOR signaling and is used in biochemical and cell-based studies. It also inhibits DNA-PK and has been reported to induce autophagy.
- Potent PI3K and mTOR inhibitor with reported low-nanomolar IC50s (p110α 8 nM; mTORC1 20 nM).
- Also inhibits DNA-PK (IC50 2 nM).
- Used for biochemical and cell-based research; for research use only.
- Stable as a powder at -20°C (up to 3 years) or 4°C (up to 2 years).
- Recommended in-solution storage: -80°C (1 year) or -20°C (6 months).
- Supplied in milligram-scale quantities suitable for analytical and cellular studies.
eMolecules 1038915-73-9 | Medchem Express | Niraparib (tosylate) | 5mg | 446258956 | HY-10619B | MFCD28167748 | 492.59 | C26H28N4O4S
Ambeed | (11bR)-N-(26-Bis(4-methoxyphenyl)-4-oxido-89101112131415-octahydrodinaphtho[21-d12-f][132]dioxaphosphepin-4-yl)-111-trifluoromethanesulfonamide | 100mg | 633659999 | A1258444 | 1071853-99-0 | 699.680 | C35H33F3NO7PS
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Medchemexpress LLC HY-15418 50mg , RS 504393 CAS:300816-15-3 Purity:98%
Medchemexpress, HY-15418 50mg RS 504393 CAS:300816-15-3 Formula:C25H27N3O3 IC50: 98 nM (CCR2b) Purity:98% RS 504393 is a selective CCR2 chemokine receptor antagonist ( IC 50 values are 98 nM and > 100 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC PI-1840 1401223-22-0 50mg
PI-1840 (CAS 1401223-22-0) is a potent selective and rapidly reversible noncovalent inhibitor of the proteasome chymotrypsin-like (CT-L) activity It exhibits an IC50 of 27 nM against CT-L catalytic function of the proteasome with significantly greater selectivity over other proteolytic activities including PGPH-L and T-L In MDA-MB-468 human breast cancer cells PI-1840 inhibits CT-L activity (IC50 0 37 M) suppresses cell viability and proliferation and induces accumulation of CT-L substrates such as I B- p27 and Bax ultimately triggering apoptosis via PARP cleavage and caspase-3 activation In vivo PI-1840 markedly reduces tumor growth in a breast cancer xenograft model This compound is valuable for investigating proteasome function apoptosis and cancer biology
Apexbio Technology LLC PI-3065 955977-50-1 50mg
PI-3065 (CAS 955977-50-1) is a selective small-molecule inhibitor targeting the phosphoinositide 3-kinase delta (PI3K ) isoform It exhibits potent inhibitory activity with reported Ki and IC50 values of approximately 1 5 nM and 5 nM respectively PI-3065 demonstrates marked selectivity showing significantly lower inhibitory potency against the related isoforms PI3K PI3K and PI3K In preclinical models treatment with PI-3065 suppressed growth and metastasis of 4T1 tumors extended survival and reduced tumor-related pathological outcomes This compound serves as a valuable tool for studying PI3K -driven signaling pathways in oncology and immunology research contexts
Accela Chembio Inc (3s | 4r)-4-(4-fluorophenyl)-1-methyl-3-piperidinemethanol | 25g | 105812-81-5 | MFCD06658161 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
(3s | 4r)-4-(4-fluorophenyl)-1-methyl-3-piperidinemethanol | 25g | 105812-81-5 | MFCD06658161 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
Apexbio Technology LLC Quisinostat dihydrochloride 875320-31-3 10mg
Quisinostat dihydrochloride (CAS 875320-31-3) also known as JNJ-26481585 dihydrochloride is an orally bioavailable pan-histone deacetylase (HDAC) inhibitor It potently suppresses the enzymatic activity of several HDAC isoforms including HDAC1 (IC50 0 11 nM) HDAC2 (IC50 0 33 nM) HDAC4 (IC50 0 64 nM) HDAC10 (IC50 0 46 nM) and HDAC11 (IC50 0 37 nM) By interfering with histone deacetylation Quisinostat dihydrochloride induces apoptosis and cell cycle arrest in tumor cells This compound is widely utilized in studies addressing tumor biology and epigenetic regulation
eMolecules 184637-48-7 | 3-Aminopiperidine, N1-BOC protected | Apollo Scientific | MFCD01861219 | 200.282 | C10H20N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC(N)C1 | 100g | 840083430
3-Aminopiperidine, N1-BOC protected | Apollo Scientific | 184637-48-7 | MFCD01861219 | 200.282 | C10H20N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC(N)C1 | 100g | 840083430
eMolecules 184637-48-7 | 1-Boc-3-aminopiperidine | Combi-Blocks | MFCD01861219 | 200.282 | C10H20N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC(N)C1 | 1g | 117518455
1-Boc-3-aminopiperidine | Combi-Blocks | 184637-48-7 | MFCD01861219 | 200.282 | C10H20N2O2 | 97.000 | CC(C)(C)OC(=O)N1CCCC(N)C1 | 1g | 117518455
MSC Made in USA SSMS-250-632-N #6-32 UNC, 1/4" Length of Thread, Soft Tip Point Set Screw Nylon
Made in USA SSMS-250-632-N #6-32 UNC, 1/4" Length of Thread, Soft Tip Point Set Screw Nylon
Selleck Chemical LLC YYA-021
YYA-021 is a CD4-mimic HIV entry inhibitor competitively inhibiting the interaction between gp120 and CD4
Medchemexpress LLC GDC-0276 10mg | 1494581-70-2 | 10 MG
GDC-0276 is a small-molecule NaV1.7 (voltage-gated sodium channel 1.7) inhibitor supplied as a solid white to off-white powder for research use only. It is provided with supporting documentation including a datasheet, COA, and SDS.
- High purity 99.69%
- Molecular formula C24H31FN2O4S
- Molecular weight 462.58
- Physical form solid, white to off-white
- Supplied as a 10 mg vial
- For research use only; not for human or diagnostic use