Piperidines
Apexbio Technology LLC LDN 209929 dihydrochloride 10mg
LDN 209929 dihydrochloride is a small-molecule inhibitor targeting haspin kinase a serine/threonine kinase It is designed to inhibit haspin kinase activity thereby regulating chromosomal alignment and mitotic progression LDN 209929 dihydrochloride exerts its biological activity primarily through selective inhibition of haspin kinase It demonstrates an IC50 of approximately 55 nM and exhibits around 180-fold selectivity over DYRK2 kinase Based on these pharmacological properties LDN 209929 dihydrochloride holds research potential in oncology studies related to aberrant mitotic control and tumor cell proliferation
STA PHARMACEUTICAL US LLC Fmoc-DL-hPro-OH | 50 g | CAS 105751-19-7 | MDL MFCD01823265
Fmoc-DL-hPro-OH is a Amino Acid reagent (Subcategory: Homo-natural AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 105751-19-7
- MDL: MFCD01823265
- InChIKey: CKLAZLINARHOTG-UHFFFAOYSA-N
- Molecular Weight: 351.402
- Molecular Formula: C21H21NO4
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29333999
- Country Of Origin: China
- IUPAC: 1-(((9H-fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid
- SMILES: O=C(N1CCCCC1C(O)=O)OCC2C3=CC=CC=C3C4=CC=CC=C42
eMolecules Piperidine-2,6-dicarboxylic acid | 499-82-1 | MFCD00986614 | 1g
Combi-Blocks | Piperidine-2,6-dicarboxylic acid | 1g | 205413456 | ST-6994 | 98.000 | 499-82-1 | MFCD00986614 | 173.168 | C7H11NO4
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Apexbio Technology LLC Vanoxerine dihydrochloride 67469-78-7 25mg
Vanoxerine dihydrochloride is a small-molecule inhibitor targeting the dopamine transporter (DAT1) human ether- -go-go-related gene (hERG Kv11 1) potassium channel cardiac sodium channel (hNaV1 5) and L-type calcium channels (ICa L) It modulates neurotransmitter uptake and cardiac ion channel conductance thereby regulating synaptic dopamine levels and cardiac electrophysiology Vanoxerine dihydrochloride exerts its biological activity primarily through inhibition of dopamine reuptake and blockade of multiple cardiac ion channels It demonstrates antagonist activity at DAT1 (Ki 16 9 nM) potent inhibition of hERG channels (IC50 0 84 nM) and inhibitory effects on hNaV1 5 (IC50 830 nM) and ICa L (IC50 320 nM) Based on these pharmacological properties vanoxerine dihydrochloride holds research potential in cardiac arrhythmia studies
Medchemexpress LLC HY-105545 50mg Medchemexpress, Dexetimide CAS:21888-98-2 Purity:>98%
Medchemexpress, HY-105545 50mg Dexetimide CAS:21888-98-2 Dexetimide ((+)-Benzetimide) is a high-affinity muscarinic receptor antagonist and a potent and persistent anticholinergic agent used to treat neuroleptic-induced parkinsonism. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Autophagy/Cytotoxicity Dual Staining Kit (MDC/PI) 500tests
Autophagy Cytotoxicity Dual Staining Kit MDC PI is a dual-fluorescent dye kit designed to assess autophagic activity and cytotoxicity in live cells It employs monodansylcadaverine (MDC) which labels autophagic vacuoles by associating with acidic lipid-containing compartments and propidium iodide (PI) which stains cells with compromised membranes indicative of severe injury or cell death Autophagy Cytotoxicity Dual Staining Kit MDC PI enables simultaneous detection of autophagy and cytotoxicity by fluorescent staining In cell-based studies it allows real-time visualization and analysis of autophagic activity and cell membrane integrity Based on these properties Autophagy Cytotoxicity Dual Staining Kit MDC PI is suitable for research applications in autophagy cytotoxicity pharmacological assessment and mechanistic studies related to disease models
Apexbio Technology LLC Hoechst 33342/PI Double Staining Kit 500T
Hoechst 33342 PI Double Staining Kit is a fluorescence-based assay kit designed to distinguish apoptosis and necrosis in cell populations The kit utilizes two fluorescent probes Hoechst 33342 and propidium iodide (PI) to assess plasma membrane integrity and nuclear morphology Hoechst 33342 penetrates live cells and binds to DNA producing blue fluorescence with intensity increasing upon apoptotic chromatin condensation PI is impermeable to intact cell membranes and selectively labels necrotic cells with red fluorescence Compared to single-stain apoptosis assays this dual-stain approach enables simultaneous detection of viable apoptotic and necrotic cells Based on these properties Hoechst 33342 PI Double Staining Kit is applicable in pharmacological evaluation and cytotoxicity studies
Medchemexpress LLC ERRα ligand-linker conjugates 1 | 00-00-0 | 98.8% | C24H20F9N3O5 | 10MG
ERRα ligand-linker conjugate combines an ERRα-targeting ligand with a PROTAC-compatible linker to serve as a building block for synthesis of ERRα-directed degraders and related conjugates. Supplied as a solid with documented purity, molecular properties, and recommended storage for research applications.
- Designed for use in PROTAC synthesis and conjugation.
- High purity: 98.8%.
- Molecular weight: 601.42 g·mol⁻¹.
- Molecular formula: C24H20F9N3O5.
- Soluble in DMSO up to 200 mg/mL; ultrasonic may be needed.
- Appearance: light yellow to yellow solid.
- Recommended storage: store under nitrogen at -20°C; in solution keep at -80°C for long-term.