Piperidines
Medchemexpress LLC HY-B0563B 10mg Medchemexpress, Ropivacaine hydrochloride CAS:98717-15-8 Purity:>98%
Medchemexpress, HY-B0563B 10mg Ropivacaine hydrochloride CAS:98717-15-8 Ropivacaine hydrochloride is an inhibitor of K 2P (two-pore domain potassium channel) TREK-1 with an IC 50 of 402.7 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC IOWH-032 | 1191252-49-9 | 99.6% | 545.18 | 500 MG
IOWH-032 is a synthetic anti-secretory molecule and a potent CFTR inhibitor with an IC50 value of 8 μM. It also functions as an anti-diarrheal agent, making it suitable for cholera, secretory diarrhea, and general diarrhea research.
- Potent CFTR inhibitor with an IC50 value of 8 μM
- Functions as an anti-diarrheal agent
- Increases ACE-2 expression in SARS-CoV-2 infected CFBE41o-WT cells
- Suitable for in vitro and in vivo studies
- Available with detailed datasheet and safety information
eMolecules 850040-18-5 | 6-(1-Azepanyl)-3-pyridinamine | Combi-Blocks, Inc. | MFCD08700222 | 191.278 | C11H17N3 | 96.000 | Nc1ccc(nc1)N1CCCCCC1 | 25g | 603130398
6-(1-Azepanyl)-3-pyridinamine | Combi-Blocks, Inc. | 850040-18-5 | MFCD08700222 | 191.278 | C11H17N3 | 96.000 | Nc1ccc(nc1)N1CCCCCC1 | 25g | 603130398
Medchemexpress LLC JNJ-1013 | 2597343-08-1 | 99.8% | 878.05 g/mol | C46H55N9O7S | 10 MG
JNJ-1013 is a research-grade PROTAC degrader that selectively targets interleukin-1 receptor-associated kinase 1 (IRAK1). It induces IRAK1 degradation, modulates downstream signaling, and has been characterized in cellular assays for apoptosis and pathway inhibition. Supplied as a high-purity solid, it is intended for in vitro biochemical and cellular studies.
- Potent IRAK1 activity with reported IC50 values: 72 nM (IRAK1), 443 nM (IRAK4), 1,071 nM (VHL FP).
- High reported purity (99.8%).
- Molecular weight 878.05 g/mol; formula C46H55N9O7S.
- Soluble in DMSO at 25 mg/mL; may require warming or sonication.
- Recommended storage: protect from light at 4°C; in solution store at -80°C for long-term or -20°C up to one month.
- Suitable for in vitro target validation, signaling pathway studies, and apoptosis assays.
eMolecules 138007-24-6 | tert-Butyl 4-Piperidinecarboxylate | Accela ChemBio | MFCD02684429 | 185.267 | C10H19NO2 | 98.000 | CC(C)(C)OC(=O)C1CCNCC1 | 10g | 796984131
tert-Butyl 4-Piperidinecarboxylate | Accela ChemBio | 138007-24-6 | MFCD02684429 | 185.267 | C10H19NO2 | 98.000 | CC(C)(C)OC(=O)C1CCNCC1 | 10g | 796984131
eMolecules 72518-41-3 | 2-Methyl-2-piperidinecarboxylic acid | Combi-Blocks | MFCD01318631 | 143.186 | C7H13NO2 | 96.000 | CC1(CCCCN1)C(O)=O | 1g | 537621042
2-Methyl-2-piperidinecarboxylic acid | Combi-Blocks | 72518-41-3 | MFCD01318631 | 143.186 | C7H13NO2 | 96.000 | CC1(CCCCN1)C(O)=O | 1g | 537621042
Sigma Aldrich Fine Chemicals Biosciences Donepezil hydrochloride >=98% (HPLC) | 120011-70-3 | MFCD00881312 | 10MG
Donepezil hydrochloride >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 415.95 | 120011-70-3 | MFCD00881312 | 10MG
Medchemexpress LLC Valopicitabine (dihydrochloride) | 640725-71-9 | MFCD34589916 | 99.8% | 429.3 g/mol | C15H26Cl2N4O6 | 50 MG
Valopicitabine (dihydrochloride) is the dihydrochloride salt of valopicitabine (NM-283), a nucleoside-analog prodrug of 2'-C-methylcytidine with activity against hepatitis C virus through inhibition of the NS5B RNA polymerase. It is provided as a research reagent for biochemical and antiviral studies.
- High purity suitable for analytical and biological assays.
- Dihydrochloride salt form, improving aqueous solubility compared with the free base.
- Acts as an orally bioavailable prodrug of an HCV polymerase inhibitor.
- Molecular weight 429.3 g/mol; formula C15H26Cl2N4O6.
- Supplied in small research quantities (e.g., 50 MG) for laboratory use.
- Accompanied by analytical documentation such as COA, H NMR, and LC-MS.
Medchemexpress LLC (R,R)-GSK321 | 1816272-19-1 | 99.36% | 100 MG
(R,R)-GSK321 is a high-purity wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor. This compound acts as an isomer of GSK321, exhibiting potent inhibition with an IC50 value of 120 nM. It also functions as a mutant R132H IDH1 inhibitor with some wild-type cross-reactivity, making it a valuable tool for relevant research.
- Inhibits wild-type isocitrate dehydrogenase 1 (WT IDH1)
- IC50 value of 120 nM
- Functions as a mutant R132H IDH1 inhibitor
- High purity of 99.36%
- Appearance as a white to off-white solid
- For research use only
Medchemexpress LLC HY-114363A 10mg Medchemexpress, SRI 31215 (TFA) CAS:1832686-44-8 Purity:>98%
Medchemexpress, HY-114363A 10mg SRI 31215 (TFA) CAS:1832686-44-8 SRI 31215 (TFA), a triplex inhibitor of matriptase, hepsin and hepatocyte growth factor activator (HGFA) with IC50s of 0.69 μM, 0.65 μM, 0.3 μM, blocks pro-HGF activation and thus mimics the activity of HAI-1/2. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
TARGETMOL CHEMICALS INC KARTOGENIN 50MG
Also available in 2 mg 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Kartogenin (KGN) is an activator of the smad4/smad5 pathway and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes. purity: 96%
eMolecules 106-52-5 | N-METHYL-4-PIPERIDINOL | AstaTech | MFCD00006500 | 115.176 | C6H13NO | 98.000 | CN1CCC(O)CC1 | 250g | 449737668
N-METHYL-4-PIPERIDINOL | AstaTech | 106-52-5 | MFCD00006500 | 115.176 | C6H13NO | 98.000 | CN1CCC(O)CC1 | 250g | 449737668
eMolecules 935693-62-2 | BIX-01294 | MFCD14560563 | 50mg
Ambeed | BIX-01294 | 50mg | 525190378 | A337768 | 935693-62-2 | MFCD14560563 | 490.652 | C28H38N6O2
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