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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences BMS-195614 >=97% (HPLC) | 182135-66-6 | MFCD00952209 | 5MG
BMS-195614 >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 448.51 | 182135-66-6 | MFCD00952209 | 5MG
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![Medchemexpress LLC (S)-1-((2',6-bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine | 1815613-42-3 | 98.8% | C19H23F4N3O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261307.png-250.jpg)
Medchemexpress LLC (S)-1-((2',6-bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine | 1815613-42-3 | 98.8% | C19H23F4N3O | 10MG
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A small-molecule, CNS-penetrant AAK1 inhibitor supplied as a solid for research use. It is characterized for preclinical in vitro and in vivo studies, with documented purity, solubility in DMSO, and recommended storage conditions for solid and solution forms.
- CNS-penetrant AAK1 inhibitor suitable for neuropathic pain research.
- High purity (≈98.8%) appropriate for analytical and pharmacology studies.
- Off-white to light yellow solid with defined storage recommendations.
- Soluble in DMSO at high concentration; example in vivo formulations provided.
- Supplied for research use only; not for human therapeutic use.
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eMolecules Ambeed / 24-Diamino-6-piperidinopyrimidine / 250mg / 506388832 / A169864 / / 24867-26-3 / MFCD04973589 / 193.254 / C9H15N5
Ambeed / 24-Diamino-6-piperidinopyrimidine / 250mg / 506388832 / A169864 / / 24867-26-3 / MFCD04973589 / 193.254 / C9H15N5
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Medchemexpress LLC HY-108361 10mg Medchemexpress, CCG-203971 CAS:1443437-74-8 Purity:>98%
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Medchemexpress, HY-108361 10mg CCG-203971 CAS:1443437-74-8 CCG-203971 is a second-generation Rho/MRTF/SRF pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC50 =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC50 of 4.2 μM. Potential anti-metastasis Agent. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC N-piperidine Ibrutinib hydrochloride | 2231747-18-3 | 98.1% | 1 ML
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N-piperidine Ibrutinib hydrochloride is a reversible Ibrutinib derivative and a potent BTK inhibitor. It demonstrates high efficacy with IC50s of 51.0 nM for WT BTK and 30.7 nM for C481S BTK. This compound serves as a valuable BTK ligand in the synthesis of various PROTACs, including potent PROTAC BTK degraders.
- Potent BTK inhibitor
- Reversible Ibrutinib derivative
- Useful as a BTK ligand for PROTAC synthesis
- Effective against both WT BTK and C481S BTK
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Ambeed AMBEED
NC3934187 R-3-METHYLPIPERIDINE HCL
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Apexbio Technology LLC PI-3065 955977-50-1 10mM (in 1mL DMSO)
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PI-3065 (CAS 955977-50-1) is a selective small-molecule inhibitor targeting the phosphoinositide 3-kinase delta (PI3K ) isoform It exhibits potent inhibitory activity with reported Ki and IC50 values of approximately 1 5 nM and 5 nM respectively PI-3065 demonstrates marked selectivity showing significantly lower inhibitory potency against the related isoforms PI3K PI3K and PI3K In preclinical models treatment with PI-3065 suppressed growth and metastasis of 4T1 tumors extended survival and reduced tumor-related pathological outcomes This compound serves as a valuable tool for studying PI3K -driven signaling pathways in oncology and immunology research contexts
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Medchemexpress LLC BSJ-03-204 (triTFA) | 2349356-09-6 | 99.8% | 832.90 | 50 MG
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BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader with anti-cancer activity, and does not induce IKZF1/3 degradation.
- Potent anti-proliferative effects on MCL cell lines
- Potently induces a G1 arrest
- Selective degradation of CDK4/6 in WT cells
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eMolecules 3-Aminopiperidine-2,6-dione hydrobromide | 90802-45-2 | MFCD30573975 | 1g
Ambeed | 3-Aminopiperidine-2,6-dione hydrobromide | 1g | 490522815 | A172642 | | 90802-45-2 | MFCD30573975 | 209.043 | C5H9BrN2O2
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eMolecules EMOLECULES INC
5000482055 1-BOC-3-AMINOPIPERIDINE 10G
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American Radiolabeled Chemicals Inc DONEPEZIL HCL 10ME
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Donepezil hydrochloride 10mg as solid, M.W. 415.99, Solvent: Solid, CAS# 120011-70-3
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Chemscene ChemScene | Methyl N-Boc-4-hydroxypiperidine-2-carboxylate | 250MG | CS-D0875 | 0.97 | 187753-13-5| MFCD08437533 | 259.3
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ChemScene | Methyl N-Boc-4-hydroxypiperidine-2-carboxylate | 250MG | CS-D0875 | 0.97 | 187753-13-5| MFCD08437533 | 259.3
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Accela Chembio Inc N-boc-4-nortropinone | 25g | 185099-67-6 | MFCD00673779 | 98% | Shelf Life: 1980 Days | Regular
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N-boc-4-nortropinone | 25g | 185099-67-6 | MFCD00673779 | 98% | Shelf Life: 1980 Days | Regular
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![Medchemexpress LLC 1-[3-(2,3-dichlorophenyl)-2H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methylpiperidin-4-amine | 2160546-07-4 | 100.0% | C17H18Cl2N6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261615.png-250.jpg)
Medchemexpress LLC 1-[3-(2,3-dichlorophenyl)-2H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methylpiperidin-4-amine | 2160546-07-4 | 100.0% | C17H18Cl2N6 | 10MG
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IACS-13909 is a selective, potent, orally active allosteric inhibitor of SHP2 (PTPN11) used as a research compound to probe MAPK pathway signaling and antitumor activity in RTK-dependent models. It provides defined potency, high supplied purity, and solubility/formulation data to support in vitro and in vivo pharmacology studies.
- Selective SHP2 allosteric inhibitor with IC50 15.7 nM and Kd 32 nM.
- High supplied purity (99.97%) suitable for biological assays.
- Soluble in DMSO at 10 mg/mL for in vitro use, with in vivo formulation options.
- Available in multiple solid and solution pack sizes for flexible dosing.
- Applicable to cellular and preclinical pharmacology studies of MAPK pathway signaling.
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![eMolecules tert-butyl 2-oxa-6-azaspiro[3.5]nonane-6-carboxylate | 1245816-29-8 | MFCD12545892 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502136233.JPG-250.jpg)
eMolecules tert-butyl 2-oxa-6-azaspiro[3.5]nonane-6-carboxylate | 1245816-29-8 | MFCD12545892 | 1g
Pharmablock | tert-butyl 2-oxa-6-azaspiro[3.5]nonane-6-carboxylate | 1g | 551136043 | PBN20120629 | | 1245816-29-8 | MFCD12545892 | 227.304 | C12H21NO3
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