Pyridines and derivatives
1,3-Dichloroisoquinoline 98.0+%, TCI America™
CAS: 7742-73-6 Molecular Formula: C9H5Cl2N Molecular Weight (g/mol): 198.046 MDL Number: MFCD00034750 InChI Key: BRGZEQXWZWBPJH-UHFFFAOYSA-N Synonym: isoquinoline, 1,3-dichloro,1,3-dichloro-isoquinoline,pubchem7254,1, 3-dichloroisoquinoline,acmc-209p9x,ksc493q3b,1,3-dichloroisoquinoline PubChem CID: 298625 IUPAC Name: 1,3-dichloroisoquinoline SMILES: C1=CC=C2C(=C1)C=C(N=C2Cl)Cl
3-Methylpyridine N-Oxide 98.0+%, TCI America™
CAS: 1003-73-2 Molecular Formula: C6H7NO Molecular Weight (g/mol): 109.128 MDL Number: MFCD00006203 InChI Key: DMGGLIWGZFZLIY-UHFFFAOYSA-N Synonym: 3-methylpyridine 1-oxide,3-picoline-n-oxide,3-picoline n-oxide,3-methylpyridine n-oxide,3-methylpyridine-n-oxide,pyridine, 3-methyl-, 1-oxide,3-picoline 1-oxide,beta-picoline n-oxide,3-methylpyridin-1-ium-1-olate,3-methylpyridine-1-oxide PubChem CID: 13858 IUPAC Name: 3-methyl-1-oxidopyridin-1-ium SMILES: CC1=C[N+](=CC=C1)[O-]
2,6-Dichloro-3-pyridinecarboxaldehyde 98.0+%, TCI America™
CAS: 55304-73-9 Molecular Formula: C6H3Cl2NO Molecular Weight (g/mol): 176.00 MDL Number: MFCD07369746 InChI Key: HWTMRGXKSANEDO-UHFFFAOYSA-N Synonym: 2,6-Dichloronicotinaldehyde, 2,6-Dichloro-3-formylpyridine PubChem CID: 12259383 IUPAC Name: 2,6-dichloropyridine-3-carbaldehyde SMILES: ClC1=NC(Cl)=C(C=O)C=C1
2-Amino-5-cyanopyridine 98.0+%, TCI America™
CAS: 4214-73-7 Molecular Formula: C6H6N3 Molecular Weight (g/mol): 120.13 MDL Number: MFCD00128902 InChI Key: KDVBYUUGYXUXNL-UHFFFAOYSA-O Synonym: 2-amino-5-cyanopyridine,6-aminonicotinonitrile,6-amino-3-pyridinecarbonitrile,6-amino-nicotinonitrile,3-pyridinecarbonitrile, 6-amino,2-amino-5-cyano pyridine,6-aminonicotinonitril,zlchem 518,pubchem5752,acmc-209jnu PubChem CID: 818260 IUPAC Name: 2-amino-5-cyanopyridin-1-ium SMILES: NC1=CC=C(C=[NH+]1)C#N
4-(m-Tolylamino)pyridine-3-sulfonamide 98.0+%, TCI America™
CAS: 72811-73-5 Molecular Formula: C12H13N3O2S Molecular Weight (g/mol): 263.315 MDL Number: MFCD00661332 InChI Key: ZXPCUGWAKUIOOF-UHFFFAOYSA-N Synonym: 4-(3-Methylphenyl)aminopyridine-3-sulfonamide, 4-(m-Tolylamino)-3-sulfamoylpyridine, 4-(3-Methylphenyl)amino-3-sulfamoylpyridine PubChem CID: 819349 IUPAC Name: 4-(3-methylanilino)pyridine-3-sulfonamide SMILES: CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)N
Apexbio Technology LLC TG100713 925705-73-3 25mg
TG100713 (CAS 925705-73-3) is a small-molecule pan-PI3K inhibitor targeting the PI3K PI3K PI3K and PI3K isoforms with IC50 values of 50 nM 24 nM 165 nM and 215 nM respectively By inhibiting pro-inflammatory PI3K and PI3K subtypes TG100713 is utilized in biomedical research to study the modulation of inflammatory responses and tissue injury associated with ischemia/reperfusion such as in myocardial infarction Studies have shown that TG100713 displays high conformational flexibility which correlates with broad isoform activity and minimal subtype selectivity This compound is valuable for investigating PI3K-driven signaling pathways and therapeutic strategies to limit tissue damage following ischemic events
Apexbio Technology LLC TG100713 925705-73-3 5mg
TG100713 (CAS 925705-73-3) is a small-molecule pan-PI3K inhibitor targeting the PI3K PI3K PI3K and PI3K isoforms with IC50 values of 50 nM 24 nM 165 nM and 215 nM respectively By inhibiting pro-inflammatory PI3K and PI3K subtypes TG100713 is utilized in biomedical research to study the modulation of inflammatory responses and tissue injury associated with ischemia/reperfusion such as in myocardial infarction Studies have shown that TG100713 displays high conformational flexibility which correlates with broad isoform activity and minimal subtype selectivity This compound is valuable for investigating PI3K-driven signaling pathways and therapeutic strategies to limit tissue damage following ischemic events
Apexbio Technology LLC TG100713 925705-73-3 10mg
TG100713 (CAS 925705-73-3) is a small-molecule pan-PI3K inhibitor targeting the PI3K PI3K PI3K and PI3K isoforms with IC50 values of 50 nM 24 nM 165 nM and 215 nM respectively By inhibiting pro-inflammatory PI3K and PI3K subtypes TG100713 is utilized in biomedical research to study the modulation of inflammatory responses and tissue injury associated with ischemia/reperfusion such as in myocardial infarction Studies have shown that TG100713 displays high conformational flexibility which correlates with broad isoform activity and minimal subtype selectivity This compound is valuable for investigating PI3K-driven signaling pathways and therapeutic strategies to limit tissue damage following ischemic events
Apexbio Technology LLC TG100713 925705-73-3 1mg
TG100713 (CAS 925705-73-3) is a small-molecule pan-PI3K inhibitor targeting the PI3K PI3K PI3K and PI3K isoforms with IC50 values of 50 nM 24 nM 165 nM and 215 nM respectively By inhibiting pro-inflammatory PI3K and PI3K subtypes TG100713 is utilized in biomedical research to study the modulation of inflammatory responses and tissue injury associated with ischemia/reperfusion such as in myocardial infarction Studies have shown that TG100713 displays high conformational flexibility which correlates with broad isoform activity and minimal subtype selectivity This compound is valuable for investigating PI3K-driven signaling pathways and therapeutic strategies to limit tissue damage following ischemic events
Apexbio Technology LLC Vandetanib (ZD6474) 443913-73-3 100mg
Vandetanib (ZD6474 CAS 443913-73-3) is a small molecule inhibitor targeting both vascular endothelial growth factor receptor 2 (VEGFR-2) and epidermal growth factor receptor (EGFR) tyrosine kinases with IC50 values of 40 nM and 500 nM respectively In biochemical assays vandetanib displays stronger inhibitory activity toward VEGFR-2 compared to VEGFR-3 and VEGFR-1 In human umbilical vein endothelial cells it suppresses VEGF- and EGF-induced proliferation with IC50 values of 60 nM and 170 nM respectively Vandetanib has been shown to inhibit the growth of various cancer cell lines and to reduce tumor progression in xenograft models supporting its utility in studies of angiogenesis and targeted cancer therapies
Apexbio Technology LLC Vandetanib (ZD6474) 443913-73-3 25mg
Vandetanib (ZD6474 CAS 443913-73-3) is a small molecule inhibitor targeting both vascular endothelial growth factor receptor 2 (VEGFR-2) and epidermal growth factor receptor (EGFR) tyrosine kinases with IC50 values of 40 nM and 500 nM respectively In biochemical assays vandetanib displays stronger inhibitory activity toward VEGFR-2 compared to VEGFR-3 and VEGFR-1 In human umbilical vein endothelial cells it suppresses VEGF- and EGF-induced proliferation with IC50 values of 60 nM and 170 nM respectively Vandetanib has been shown to inhibit the growth of various cancer cell lines and to reduce tumor progression in xenograft models supporting its utility in studies of angiogenesis and targeted cancer therapies
Medchemexpress LLC Cefaclor | 53994-73-3 | 98.5% | 5 G
Cefaclor is a well-absorbed orally active cephalosporin antibiotic. It specifically binds to penicillin-binding protein 3 (PBP3) and is used for research into depression and various bacterial infections, including respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections.
- Well-absorbed orally active cephalosporin antibiotic
- Specifically binds to penicillin-binding protein 3 (PBP3)
- Used for research of depression and various bacterial infections
- Shows significant antibacterial activity against Gram-positive and Gram-negative isolates
Medchemexpress LLC Cefaclor | 53994-73-3 | 98.5% | 1 G
Cefaclor is a well-absorbed orally active cephalosporin antibiotic. It specifically binds to penicillin-binding protein 3 (PBP3) and can be used for research on depression and various bacterial infections, including respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections. This product is intended for research and analytical applications only and has not been fully validated for medical use.
- Well-absorbed orally active cephalosporin antibiotic
- Specifically binds to penicillin-binding protein 3 (PBP3)
- Used for research on depression
- Effective against various bacterial infections including respiratory tract infections, bacterial bronchitis, pharyngitis, and skin infections
- Provided as a light yellow to yellow solid
Medchemexpress LLC 6-CEPN 5mg | 1054549-73-3 | 5 MG
6-CEPN is a small-molecule RAS inhibitor that binds Icmt sites, showing anticancer activity by blocking cells in the G1 phase and inducing autophagy and necrosis. Supplied for research use in small-mass packs.
- Inhibits RAS activation by targeting Icmt binding sites.
- Induces autophagy and necrosis in cancer cells.
- Useful for studies of ras signaling, autophagy, and cell-cycle regulation.
- Provided in small-mass packs suitable for in vitro assays.
- Soluble in DMSO at 100 mg/mL; formulation guidance provided for in vivo dosing vehicles.