Pyridines and derivatives
3,6-Dibromo-2-chloropyridine, 95%, Thermo Scientific Chemicals
CAS: 942206-18-0 Molecular Formula: C5H2Br2ClN Molecular Weight (g/mol): 271.336 MDL Number: MFCD09037464 InChI Key: CVZSNXGMWIGPBF-UHFFFAOYSA-N Synonym: 2-chloro-3,6-dibromopyridine,3,6-dibromo-2-chloro-pyridine PubChem CID: 42553063 IUPAC Name: 3,6-dibromo-2-chloropyridine SMILES: C1=CC(=NC(=C1Br)Cl)Br
3,6-Dichloropyridine-2-carboxylic acid, 96%
CAS: 1702-17-6 Molecular Formula: C6H3Cl2NO2 Molecular Weight (g/mol): 192.00 MDL Number: MFCD00078655 InChI Key: HUBANNPOLNYSAD-UHFFFAOYSA-N Synonym: clopyralid,3,6-dichloropicolinic acid,3,6-dichloro-2-pyridinecarboxylic acid,lontrel,2-pyridinecarboxylic acid, 3,6-dichloro,clopyralide,benzalox,cirtoxin,matrigon,transline PubChem CID: 15553 ChEBI: CHEBI:62961 IUPAC Name: 3,6-dichloropyridine-2-carboxylic acid SMILES: OC(=O)C1=NC(Cl)=CC=C1Cl
2-Chloro-4-nitropyridine 98.0+%, TCI America™
CAS: 23056-36-2 Molecular Formula: C5H3ClN2O2 Molecular Weight (g/mol): 158.54 MDL Number: MFCD00661454 InChI Key: LIEPVGBDUYKPLC-UHFFFAOYSA-N Synonym: pyridine, 2-chloro-4-nitro,2-chloro-4-nitro-pyridine,2-chlor-4-nitropyridin,pubchem9220,2-chloro-4nitropyridine,2chloro-4-nitropyridine,acmc-1ccv7,2-chloro-4-nitro pyridine,ksc201q1f,2-chloro-4-nitropyridine PubChem CID: 735152 IUPAC Name: 2-chloro-4-nitropyridine SMILES: [O-][N+](=O)C1=CC(Cl)=NC=C1
2-Chloro-3-iodopyridine 98.0+%, TCI America™
CAS: 78607-36-0 Molecular Formula: C5H3ClIN Molecular Weight (g/mol): 239.44 MDL Number: MFCD00661298 InChI Key: OHWSWGXNZDSHLM-UHFFFAOYSA-N Synonym: 2-chloro-3-iodo-pyridine,pyridine, 2-chloro-3-iodo,3-iodo-2-chloropyridine,zlchem 306,pubchem1188,acmc-209pes,2-chloro-3-iodopyridine,ksc378k0b,2-chloranyl-3-iodanyl-pyridine,2-choro-3-iodopyridine PubChem CID: 2735743 IUPAC Name: 2-chloro-3-iodopyridine SMILES: C1=CC(=C(N=C1)Cl)I
2-(4-Bromophenyl)pyridine 98.0+%, TCI America™
CAS: 63996-36-1 Molecular Formula: C11H8BrN Molecular Weight (g/mol): 234.096 MDL Number: MFCD04116231 InChI Key: FBQFCXDBCPREBP-UHFFFAOYSA-N PubChem CID: 1515237 IUPAC Name: 2-(4-bromophenyl)pyridine SMILES: C1=CC=NC(=C1)C2=CC=C(C=C2)Br
2-Amino-6-methoxy-3-nitropyridine 97.0+%, TCI America™
CAS: 73896-36-3 Molecular Formula: C6H7N3O3 Molecular Weight (g/mol): 169.14 MDL Number: MFCD03206481 InChI Key: RDJILYVRVOTMTQ-UHFFFAOYSA-N Synonym: 2-amino-6-methoxy-3-nitropyridine,2-amino-3-nitro-6-methoxypyridine,6-methoxy-3-nitro-2-pyridinamine,2-amino-3-nitro-6-methoxy pyridine,2-pyridinamine, 6-methoxy-3-nitro,6-methoxy-3-nitro-2-pyridylamine,6-methoxy-3-nitro-pyridin-2-ylamine,pubchem5689,acmc-1bcyf,ksc496m1p PubChem CID: 3852428 IUPAC Name: 6-methoxy-3-nitropyridin-2-amine SMILES: COC1=NC(=C(C=C1)[N+](=O)[O-])N
6-Bromo-4,4'-dimethyl-2,2'-bipyridyl 97.0+%, TCI America™
CAS: 850413-36-4 Molecular Formula: C12H11BrN2 Molecular Weight (g/mol): 263.14 MDL Number: MFCD11042495 InChI Key: UEJJXCRFGURPDR-UHFFFAOYSA-N PubChem CID: 53438778 IUPAC Name: 6-bromo-4,4'-dimethyl-2,2'-bipyridine SMILES: CC1=CC(=NC=C1)C1=NC(Br)=CC(C)=C1
2,2':6',2″-Terpyridine-4'-carboxylic Acid 98.0+%, TCI America™
CAS: 148332-36-9 Molecular Formula: C16H11N3O2 Molecular Weight (g/mol): 277.28 MDL Number: MFCD04114290 InChI Key: ZYTWXMBGOUJDHJ-UHFFFAOYSA-N Synonym: 2,2':6',2-terpyridine-4'-carboxylic acid,2,2':6',2-terpyridine-4'-carboxylicacid,2,6-bis pyridin-2-yl pyridine-4-carboxylic acid,6-pyridin-2-yl-2,2'-bipyridine-4-carboxylic acid,acmc-1c3v7,4'-carboxy-2,2':6',2-terpyridine,2,2:6,2'-terpyridine-4-carboxylic acid,1∼2∼,2∼2∼:2∼6∼,3∼2∼-terpyridine-2∼4∼-carboxylic acid,2,2\\':6\\',2\\'\\'-terpyridine-4\\'-carboxylic acid PubChem CID: 2762749 IUPAC Name: 6-(pyridin-2-yl)-[2,2'-bipyridine]-4-carboxylic acid SMILES: OC(=O)C1=CC(=NC(=C1)C1=CC=CC=N1)C1=CC=CC=N1
5-Bromo-2-hydroxynicotinic Acid 98.0+%, TCI America™
CAS: 104612-36-4 Molecular Formula: C6H4BrNO3 Molecular Weight (g/mol): 218.006 MDL Number: MFCD07363801 InChI Key: GYXOTADLHQJPIP-UHFFFAOYSA-N Synonym: 5-Bromo-2-hydroxy-3-pyridinecarboxylic Acid PubChem CID: 2764024 IUPAC Name: 5-bromo-2-oxo-1H-pyridine-3-carboxylic acid SMILES: C1=C(C(=O)NC=C1Br)C(=O)O
Monomethyl 2,6-Pyridinedicarboxylate 97.0+%, TCI America™
CAS: 7170-36-7 Molecular Formula: C8H7NO4 Molecular Weight (g/mol): 181.15 MDL Number: MFCD00806109 InChI Key: VWIOMFMPIVMLIR-UHFFFAOYSA-N Synonym: 2,6-Pyridinedicarboxylic Acid Monomethyl Ester, Monomethyl Dipicolinate, Dipicolinic Acid Monomethyl Ester PubChem CID: 4019172 IUPAC Name: 6-(methoxycarbonyl)pyridine-2-carboxylic acid SMILES: COC(=O)C1=CC=CC(=N1)C(O)=O
Apexbio Technology LLC DCEBIO 60563-36-2 10mg
DCEBIO (CAS 60563-36-2) is a small molecule derivative of 1-EBIO recognized for its modulatory effects on ion channels In T84 colonic epithelial cells DCEBIO enhances chloride secretion by activating the human intermediate conductance Ca2 -activated K channel (hIK1) and facilitating apical membrane Cl- conductance thereby influencing epithelial electrolyte transport This compound is utilized in cell-based research to investigate ion channel-mediated signal transduction pathways Its ability to modulate specific ion channels supports its widespread use in studies focused on ion channel function and the modeling of disorders related to epithelial ion transport
Apexbio Technology LLC RI-2 1417162-36-7 50mg
RI-2 (CAS 1417162-36-7) is a reversible small molecule inhibitor of RAD51 a conserved protein essential for homologous recombination (HR)-mediated DNA repair RAD51 is frequently overexpressed in cancer cells making it a relevant target for oncology research RI-2 inhibits RAD51 activity with an IC50 of 44 17 M impairing RAD51-mediated DNA binding in vitro Unlike some related compounds RI-2 does not react with glutathione after 24 hours of incubation indicating it lacks irreversible Michael acceptor reactivity RI-2 is under preclinical investigation as a research tool for studying HR pathways and potential strategies to sensitize cancer cells to DNA-damaging therapies
Apexbio Technology LLC RI-2 1417162-36-7 10mg
RI-2 (CAS 1417162-36-7) is a reversible small molecule inhibitor of RAD51 a conserved protein essential for homologous recombination (HR)-mediated DNA repair RAD51 is frequently overexpressed in cancer cells making it a relevant target for oncology research RI-2 inhibits RAD51 activity with an IC50 of 44 17 M impairing RAD51-mediated DNA binding in vitro Unlike some related compounds RI-2 does not react with glutathione after 24 hours of incubation indicating it lacks irreversible Michael acceptor reactivity RI-2 is under preclinical investigation as a research tool for studying HR pathways and potential strategies to sensitize cancer cells to DNA-damaging therapies
Apexbio Technology LLC RS 09 1449566-36-2 25mg
RS 09 (CAS 1449566-36-2) is a synthetic peptide that functions as a lipopolysaccharide (LPS) mimetic It modulates immune signaling pathways by acting as an agonistic adjuvant resulting in altered biological responses Experimental studies have demonstrated that RS 09 can enhance vaccine-induced antibody production in in vitro systems Due to its defined immunomodulatory activity RS 09 is widely employed in immunology research and vaccine development to investigate mechanisms of immune activation and to optimize adjuvant formulations
Apexbio Technology LLC RS 09 1449566-36-2 5mg
RS 09 (CAS 1449566-36-2) is a synthetic peptide that functions as a lipopolysaccharide (LPS) mimetic It modulates immune signaling pathways by acting as an agonistic adjuvant resulting in altered biological responses Experimental studies have demonstrated that RS 09 can enhance vaccine-induced antibody production in in vitro systems Due to its defined immunomodulatory activity RS 09 is widely employed in immunology research and vaccine development to investigate mechanisms of immune activation and to optimize adjuvant formulations