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Filtered Search Results
Medchemexpress LLC TMP195 | 1314891-22-9 | 99.8% | 456.42 | 250 MG
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TMP195 is a selective class IIa histone deacetylase (HDAC) inhibitor. It has reported Ki values of 59, 60, 26, and 15 nM for HDAC4, HDAC5, HDAC7, and HDAC9, respectively. It is intended for research use only and not for sale to patients.
- Selective class IIa HDAC inhibitor.
- Blocks the accumulation of CCL2 protein in monocyte-derived macrophage differentiation cultures.
- Significantly increases CCL1 protein secretion by monocytes.
- Occupies the acetyllysine-binding site of class IIa HDACs.
- Alters the tumor microenvironment, reducing tumor burden and pulmonary metastases by modulating macrophage phenotypes in vivo.
- Induces recruitment and differentiation of highly phagocytic and stimulatory macrophages within tumors in vivo.
- Combining with chemotherapy regimens or T-cell checkpoint blockade enhances the durability of tumor reduction in vivo.
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Medchemexpress LLC Triacetylresveratrol | 42206-94-0 | 354.35 | 250 MG
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Triacetylresveratrol is an acetylated analog of Resveratrol. It decreases the phosphorylation of STAT3 and NF-κB in a dose- and time-dependent manner in PANC-1 and BxPC-3 cells, demonstrating anticancer effects. It significantly down-regulates the anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates the pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner.
- STAT3/NF-κB inhibitor
- Decreases the phosphorylation of STAT3 and NF-κB
- Exhibits anticancer effects
- Significantly down-regulates the anti-apoptotic Bcl-2 family protein Mcl-1
- Up-regulates the pro-apoptotic Bcl-2 family proteins Bim and Puma
- Inhibits cell viability and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner
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![eMolecules 89975-57-5 | 7-Aminopyrazolo[1?5-a]pyrimidine-6-carbonitrile | AA Blocks LLC | MFCD00104599 | 159.152 | C7H5N5 | 0.000 | Nc1c(cnc2ccnn12)C#N | 250mg | 713331631](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3966468.jpg-250.jpg)
eMolecules 89975-57-5 | 7-Aminopyrazolo[1?5-a]pyrimidine-6-carbonitrile | AA Blocks LLC | MFCD00104599 | 159.152 | C7H5N5 | 0.000 | Nc1c(cnc2ccnn12)C#N | 250mg | 713331631
7-Aminopyrazolo[1?5-a]pyrimidine-6-carbonitrile | AA Blocks LLC | 89975-57-5 | MFCD00104599 | 159.152 | C7H5N5 | 0.000 | Nc1c(cnc2ccnn12)C#N | 250mg | 713331631
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Medchemexpress LLC Ethyl 2-chloronicotinate | 1452-94-4 | MFCD00674129 | 100.0% | 185.61 g·mol-1 | C8H8ClNO2 | 500 G
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Ethyl 2-chloronicotinate (CAS 1452-94-4) is an organic research reagent used as a building block and intermediate in medicinal chemistry and related organic synthesis. It is supplied as a high-purity liquid for analytical and synthetic laboratory applications.
- High purity suitable for analytical and synthetic use.
- Colorless to light yellow liquid form for easy handling and dosing.
- Useful as a synthetic intermediate in heterocyclic and medicinal chemistry.
- Well-characterized by CAS, molecular formula, and molecular weight for traceability.
- Available in multiple pack sizes to support small-scale and larger synthesis.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC CD38 inhibitor 1 | 1700637-55-3 | MFCD32062812 | 99.3% | 413.53 | C22H27N3O3S | 250MG
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CD38 inhibitor 1 (compound 78c) is a small-molecule inhibitor of CD38 with low-nanomolar potency against human and mouse CD38 (IC50 7.3 nM and 1.9 nM, respectively). Supplied as a solid research compound, it has the chemical formula C22H27N3O3S, a molecular weight of 413.53, and typical purity of about 99.3%. It is provided in multiple package sizes and includes storage guidance for powder and solution forms.
- Low-nanomolar potency against human and mouse CD38 (IC50 7.3 nM; 1.9 nM)
- High chemical purity suitable for research applications
- Available in multiple package sizes including 250 mg
- Solid, light yellow to brown appearance for easy handling
- Stable as powder at -20°C for long-term storage and at 4°C for shorter-term storage
- Suitable for biochemical and cellular CD38 activity assays
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Medchemexpress LLC Methyl cellulose | 9004-67-5 | MFCD00081763 | 10,000-220,000 g/mol | C6H7O2(OR1)(OR2)(OR3) (polymeric anhydroglucose repeating unit) | 5G
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Methyl cellulose is a non-ionic cellulose ether supplied as a white, water-soluble powder used as a thickener, binder, film former, and stabilizer in laboratory and formulation applications. It is available in multiple viscosity grades to tailor solution rheology and typically dissolves in cold water to form clear, viscous gels.
- Non-ionic cellulose ether thickener and gelling agent.
- Multiple viscosity grades available to tailor rheology.
- Dissolves in cold water to form clear, viscous gels.
- Used as a binder, film former, stabilizer, and emulsifier.
- Supplied as a solid powder suitable for laboratory formulation.
- Safety considerations: harmful if swallowed; may irritate skin, eyes, and respiratory tract.
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eMolecules 84434-11-7 | Ethyl (2,4,6-trimethylbenzoyl)phenylphosphinate | Oakwood Chemicals | MFCD08692488 | 316.337 | C18H21O3P | 95.000 | CCOP(=O)(C(=O)c1c(C)cc(C)cc1C)c1ccccc1 | 5g | 480141418
Ethyl (2,4,6-trimethylbenzoyl)phenylphosphinate | Oakwood Chemicals | 84434-11-7 | MFCD08692488 | 316.337 | C18H21O3P | 95.000 | CCOP(=O)(C(=O)c1c(C)cc(C)cc1C)c1ccccc1 | 5g | 480141418
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eMolecules 4-BROMOMETHYLBENZALDEH 250MG
5000190300 4-BROMOMETHYLBENZALDEH 250MG
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eMolecules DBHDA 250MG
5000191512 DBHDA 250MG
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eMolecules ALLYLPALLADIUMII CHLOR 250MG
5000192098 ALLYLPALLADIUMII CHLOR 250MG
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eMolecules S---2 2-BISDIPHENYLP 250MG
5000192099 S---2 2-BISDIPHENYLP 250MG
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Medchemexpress LLC ETHYL 5- PIPERAZIN-1 5G
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ETHYL 5- PIPERAZIN-1 5G
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eMolecules 2-BENZYLOXYACETALDEHYD 250MG
5000192465 2-BENZYLOXYACETALDEHYD 250MG
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eMolecules 1-TRIFLUOROMETHYLCYCLO 100MG
5000192466 1-TRIFLUOROMETHYLCYCLO 100MG
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eMolecules 1-TRIFLUOROMETHYLCYCLOP 25MG
5000192468 1-TRIFLUOROMETHYLCYCLOP 25MG
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