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Filtered Search Results
Medchemexpress LLC 1H-Indole, 3-(2-chloro-4-pyrimidinyl)-1-methyl- | 1032452-86-0 | 99.5% | C13H10ClN3 | 100 G
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3-(2-Chloropyrimidin-4-yl)-1-methylindole (MedChemExpress HY-78866) is a high-purity chemical compound, appearing as an off-white to light yellow solid. With a molecular weight of 243.70 and a purity of 99.5%, it is suitable for various research applications.
- Appearance: Off-white to light yellow solid
- Purity: 99.5%
- Powder storage stability: 3 years at -20°C, 2 years at 4°C
- In solvent storage stability: 6 months at -80°C, 1 month at -20°C
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eMolecules ETHYL 2-NITROACETATE 1G
5000161116 ETHYL 2-NITROACETATE 1G
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Sigma Aldrich Fine Chemicals Biosciences Orotic acid potassium salt | 24598-73-0 | MFCD00039118 | 100 g
Orotic acid potassium salt | Purity: ≥98% | Mol Wt: 194.19 | 24598-73-0 | MFCD00039118 | 100 g
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Selleck Chemical LLC Dorsomorphin 2HCl
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Dorsomorphin 2HCl is a potent reversible selective AMPK inhibitor with Ki of 109 nM in cell-free assays exhibiting no significant inhibition of several structurally related kinases including ZAPK SYK PKC PKA and JAK3 Also inhibits type BMP receptor activity Dorsomorphin induces autophagy in cancer cell line
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Medchemexpress LLC (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | 1192651-49-2 | MFCD30541561 | C14H17N3O3 | 100 MG
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(2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide is an impurity of Avibactam, a novel β-lactamase inhibitor with a non-lactam structural scaffold.
- Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis.
- Synthesized using (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid as a raw material.
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eMolecules METHYL 4-METHYLBENZENESUL 100G
5000158683 METHYL 4-METHYLBENZENESUL 100G
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Medchemexpress LLC Thiamine monochloride (Vitamin B1) | 59-43-8 | 99.96% | C12H17ClN4OS | 1 ML
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Thiamine monochloride (Vitamin B1) is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal activities. It is for research use only.
- Essential vitamin
- Plays a role in cellular energy production
- Enhances normal neuronal activities
- High purity: 99.96%
- Available in both solid and solution forms
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000656101 HOMOPLANTAGININ 250MG
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Medchemexpress LLC GLPG3970 | 2403733-82-2 | C25H27F3N4O4 | 250 MG
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GLPG3970 is a first-in-class SIK2/SIK3 inhibitor intended for research related to inflammation and autoimmune diseases. It has been investigated in clinical trials for conditions such as Systemic Lupus Erythematosus, Ulcerative Colitis, and Rheumatoid Arthritis.
- Acts as a SIK2/SIK3 inhibitor
- Supports research in inflammation and autoimmune diseases
- Induces IL-10 expression in human CD14+ monocytes with an EC50 of 1087 nM
- Reduces LPS-stimulated TNF-alpha production in human CD14+ monocytes with an IC50 of 133 nM
- Decreases ear thickness in murine models of psoriatic-like epidermal hyperplasia
- Improves clinical manifestations in murine collagen-antibody induced arthritis models
- Reduces disease activity index in mice T cell transfer models
- Investigated in clinical trials for various conditions
- High purity: 99.70%
- Solid, white to off-white appearance
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Medchemexpress LLC Darizmetinib | 2369583-33-3 | C21H17F2N5O3S | 250 MG
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Darizmetinib is an orally active, potent, and selective inhibitor of mitogen-activated protein kinase kinase 4 (MKK4; MAP2K4). It selectively targets, binds to, and inhibits the activity of MKK4 in liver cells. This inhibition enhances MKK7 and JNK1 signaling pathways, activating transcription factors ATF2 and ELK1, which promotes cell proliferation and liver regeneration. Darizmetinib is promising for research to prevent liver failure after extensive oncological liver resections or transplantation of small liver grafts.
- Orally active, potent, and selective MKK4 inhibitor
- Enhances MKK7 and JNK1 signaling pathways
- Activates transcription factors ATF2 and ELK1
- Promotes hepatocyte proliferation and survival
- Aids liver regeneration following hepatectomy
- Potential to prevent liver failure and restore liver mass
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eMolecules Medchem Express / Momelotinib sulfate / 5mg / 446259630 / HY-10962 / / 1056636-06-6 / MFCD22573341 / 610.610 / C23H26N6O10S2
Medchem Express / Momelotinib sulfate / 5mg / 446259630 / HY-10962 / / 1056636-06-6 / MFCD22573341 / 610.610 / C23H26N6O10S2
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Medchemexpress LLC Hexacosanoic acid | 506-46-7 | 95.0% | 396.69 | 250 MG
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Hexacosanoic acid is a very long-chain fatty acid. Abnormally elevated levels of hexacosanoic acid are closely associated with various diseases, including X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia.
- Very long-chain fatty acid
- Associated with various diseases
- Shows antineuroinflammatory activity in mouse BV2 cells
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Medchemexpress LLC E3 ligase Ligand PG | 14149-34-9 | C11H11NO2 | 250 MG
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E3 ligase Ligand PG is an E3 ligase ligand used for the recruitment of the CRBN protein. It demonstrates potent binding activity with CRBN (IC50 of 2.191 μM) and can be connected via a linker to form PROTACs, such as PROTAC PD-L1 degrader-1. This product is for research use only.
- Used for recruitment of CRBN protein
- Demonstrates potent binding activity with CRBN (IC50 of 2.191 μM)
- Can be connected by a linker to form PROTACs
- Solid, white to off-white in appearance
- Purity of 99.94%
- Powder storage: -20°C for 3 years or 4°C for 2 years
- In solvent storage: -80°C for 6 months or -20°C for 1 month
- Soluble in DMSO at 116.67 mg/mL (616.62 mM)
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000371461 MAOS 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431272 HELICID 250MG
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