Pyrroles
eMolecules 1049741-03-8 | Medchem Express | SPD304 (dihydrochloride) | 5mg | 761953613 | HY-111255A | MFCD09265259 | 620.54 | C32H34Cl2F3N3O2
Medchem Express | Ascr5 | 5mg | 600899991 | HY-N6978 | 1086696-26-5 | 220.221 | C9H16O6
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![Medchemexpress LLC Methanone (2-chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoro-2-pyrimidinyl)-1,4,6,7-tetrahydro-4-methyl-triazolo[4,5-c]pyridin-5-yl) | 1627902-21-9 | MFCD31556312 | 99.3% | 440.8 g/mol | C18H13ClF4N6O | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000227087.png-250.jpg)
Medchemexpress LLC Methanone (2-chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoro-2-pyrimidinyl)-1,4,6,7-tetrahydro-4-methyl-triazolo[4,5-c]pyridin-5-yl) | 1627902-21-9 | MFCD31556312 | 99.3% | 440.8 g/mol | C18H13ClF4N6O | 5 MG
JNJ-54175446 is a brain-penetrant, selective P2X7 receptor antagonist used as a research tool to study neuroinflammation and central nervous system disorders. It has been characterized in preclinical and clinical research for its pharmacodynamic effects in the brain.
- Potent P2X7 antagonist with reported pIC50 8.46 (human) and 8.81 (rat).
- Brain penetrant, suitable for CNS pharmacology studies.
- High reported purity for research assays (99.3%).
- Solid, light yellow to yellow appearance for solid handling and storage.
- Molecular weight 440.8 g/mol and formula C18H13ClF4N6O.
- For research use only; not intended for clinical or therapeutic use.
Medchemexpress LLC CB-5083 | 1542705-92-9 | MFCD28963914 | 5mg
CB-5083 | Purity: 99.95% | MW: 413.479 | 1542705-92-9 | MFCD28963914 | 5mg
Medchemexpress LLC EX229, a benzimidazole derivative | 1219739-36-2 | MFCD31696597 | 99.4% | 431.87 | C24H18ClN3O3 | 5 MG
EX229 is a benzimidazole-derived small-molecule allosteric activator of AMP-activated protein kinase (AMPK) used for biochemical and cellular research. It binds AMPK complexes with submicromolar affinity and shows potent cellular activity, suitable for pathway and metabolic studies.
- Potent allosteric activator of AMPK (Kd ≈ 0.06 μM for primary complexes).
- Demonstrated cellular activity (EC50 ≈ 3 nM in Sf21 cell assay).
- High purity (≈99.4%).
- Soluble in DMSO (~13 mg/mL) with recommended in vivo formulation protocols.
- Stable as powder and in solvent when stored under recommended conditions.
- Available in small-mass packs and DMSO solutions for screening workflows.
Cayman Chemical RBromoenol lactone
A selective iPLA2γ inhibitor (IC50 = ~0.6 µM); selective for iPLA2γ over iPLA2β at 20-30 µM
Medchemexpress LLC HY-109020 5mg Medchemexpress, Acrizanib CAS:1229453-99-9 Purity:>98%
Medchemexpress, HY-109020 5mg Acrizanib CAS:1229453-99-9 Acrizanib is a VEGFR-2 inhibitor, with an IC 50 of 17.4 nM for BaF3-KDR. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.