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Filtered Search Results
Medchemexpress LLC Z-LEHD-FMK | 210345-04-3 | 98.09% | 690.72 | 25 MG
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Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9. It protects against lethal reperfusion injury and attenuates apoptosis. It also shows a neuroprotective effect in a rat model of spinal cord trauma.
- Selective and irreversible inhibitor of caspase-9.
- Protects against lethal reperfusion injury.
- Attenuates apoptosis.
- Shows neuroprotective effect in a rat model of spinal cord trauma.
- Purity of 98.09%.
- Molecular weight is 690.72.
- Appears as a white to yellow solid.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC Z-Semaxinib 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. (Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50 1.23 uM), 20-fold more selective for VEGFR over PDGFRbeta, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative with potential antineoplastic activity. Purity 99.94%
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Medchemexpress LLC 2-Oxazolidinone, 3-(1-oxo-2-buten-1-yl)-4-(phenylmethyl)-, (4S)- | 133812-16-5 | 99.5% | 245.27 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(E/Z)-Locostatin ((E/Z)-UIC-1005) is a racemic form of Locostatin. Locostatin (UIC-1005) acts as a potent RKIP inhibitor. It functions by binding to the Raf kinase inhibitor RKIP protein, thereby disrupting the interaction between RKIP and Raf-1 kinase, as well as G protein-coupled receptor kinase 2. Locostatin has been shown to inhibit cell proliferation and migration. Additionally, it has been observed to aggravate thioacetamide (HY-Y0698)-induced acute liver failure in mice.
- Racemic form of locostatin
- Potent RKIP inhibitor
- Disrupts interaction of RKIP with raf-1 kinase and G protein-coupled receptor kinase 2
- Inhibits cell proliferation and migration
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Medchemexpress LLC Z-VDVAD-FMK | 210344-92-6 | ≥98.0% | 695.73 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Z-VDVAD-FMK is a special inhibitor of caspase-2, observed to reduce Lovastatin-induced apoptosis. It significantly diminishes Lovastatin-induced DNA loss and inhibits Rho-kinase activity in HMEC-1 cells when stimulated by Thrombin.
- Inhibits caspase-2
- Reduces Lovastatin-induced apoptosis
- Prevents many morphological features of apoptosis in cotreatment with other caspase inhibitors
- Greatly inhibits Rho-kinase activity in HMEC-1 cells stimulated by Thrombin
- Significantly reduces Lovastatin-induced loss of DNA
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC E/Z-HA155 5mg | 1229652-22-5 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(E/Z)-HA155 is a small-molecule autotaxin (ATX) type I inhibitor used in preclinical research to study cancer, fibrotic diseases, inflammation, pain, and angiogenesis. Supplied as a high-purity powder with recommended cold storage, it is available in multiple pack sizes and as a DMSO solution for biological assays.
- High purity: 99.3% (rounded from manufacturer specification).
- Molecular weight approximately 463.29 g·mol⁻¹.
- Chemical formula C24H19BFNO5S.
- Recommended storage: powder at -20°C; solutions at -80°C for long-term storage.
- Available in small research quantities and as a 10 mM solution in DMSO for assay use.
- Supplied with a certificate of analysis and safety data sheet for quality and handling information.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC E/Z-HA155 10mg | 1229652-22-5 | 463.29 g/mol | C24H19BFNO5S | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor supplied for laboratory research use. It is used to support studies into cancer, fibrotic diseases, inflammation, pain, and angiogenesis. For research use only; not for human or clinical application.
- Potent autotaxin type I inhibition for biochemical assays.
- Applicable to cancer, fibrosis, inflammation, pain, and angiogenesis research.
- High purity (99.26%) suitable for cellular and biochemical experiments.
- Supplied as a small-scale powder for dose optimization and pilot studies.
- Stored and handled per standard laboratory safety procedures for research reagents.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (Z)-aconitic acid | 585-84-2 | MFCD00063184 | 99.3% | 174.11 g/mol | C6H6O6 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(Z)-Aconitic acid (cis-aconitic acid) is a research-grade organic acid (CAS 585-84-2) described as a glutamate decarboxylase inhibitor that reduces IκB-α phosphorylation. It is supplied in small quantities for biochemical and pharmacological research and is intended for laboratory research use only.
- High purity: 99.28%.
- Molecular weight: 174.11 g/mol.
- Chemical formula: C6H6O6.
- Available in small research packages including a 50 mg size.
- Solid, white to light yellow appearance.
- Intended for research use only; not for human or clinical use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 4-[4-Bromo-3-(hydroxymethyl)phenoxy]benzonitrile | ≥95% | CAS 906673-45-8 | C14H10BrNO2 | 5g
4-[4-Bromo-3-(hydroxymethyl)phenoxy]benzonitrile | ≥95% | CAS 906673-45-8 | C14H10BrNO2 | 5g
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 1-[3-(Hydroxymethyl)phenyl]ethanone | ≥95% | CAS 125604-06-0 | C9H10O2 | 250mg
1-[3-(Hydroxymethyl)phenyl]ethanone | ≥95% | CAS 125604-06-0 | C9H10O2 | 250mg
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 2-Fluoro-3-(hydroxymethyl)-5-methylpyridine | ≥97% | CAS 1227565-23-2 | C7H8FNO | 250mg
2-Fluoro-3-(hydroxymethyl)-5-methylpyridine | ≥97% | CAS 1227565-23-2 | C7H8FNO | 250mg
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 2 6-Dichloro-4-(hydroxymethyl)benzoic acid | ≥95% | CAS 1415124-96-7 | C8H6Cl2O3 | 250mg
2 6-Dichloro-4-(hydroxymethyl)benzoic acid | ≥95% | CAS 1415124-96-7 | C8H6Cl2O3 | 250mg
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Aobchem 2-Fluoro-3-(hydroxymethyl)-5-methylbenzoic acid | ≥95% | CAS 2137681-06-0 | C9H9FO3 | 5g
2-Fluoro-3-(hydroxymethyl)-5-methylbenzoic acid | ≥95% | CAS 2137681-06-0 | C9H9FO3 | 5g
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Medchemexpress LLC Hydroxymethyl dasatinib | 910297-58-4 | MFCD18252610 | 98.0% | 504.00 g/mol | C22H26ClN7O3S | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Hydroxymethyl dasatinib is the M24 benzylhydroxy metabolite of dasatinib and is supplied as a small-molecule research reagent for in vitro studies. It has been reported to inhibit proliferation of K562 chronic myeloid leukemia cells with an IC50 of 46.7 nM. This compound is intended for research use only and not for human or clinical applications.
- Benzylhydroxy metabolite of dasatinib.
- Reported IC50 of 46.7 nM in K562 cells.
- Small-molecule research reagent for in vitro studies.
- Molecular weight 504.00 g/mol.
- Chemical formula C22H26ClN7O3S.
- CAS number 910297-58-4.
- Available as 5 MG package.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem 8-(3-(Hydroxymethyl)phenyl)-1 4-dioxaspiro[4 5]decan-8-ol | 95% | C15H20O4 | 25g
8-(3-(Hydroxymethyl)phenyl)-1 4-dioxaspiro[4 5]decan-8-ol | 95% | C15H20O4 | 25g
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aobchem (2-(Hydroxymethyl)-4 5-dimethoxyphenyl)boronic acid | 95% | CAS 2055472-45-0 | C9H13BO5 | 500mg
(2-(Hydroxymethyl)-4 5-dimethoxyphenyl)boronic acid | 95% | CAS 2055472-45-0 | C9H13BO5 | 500mg
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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