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Filtered Search Results
Apexbio Technology LLC N-Ethylmaleimide (NEM) 128-53-0 1g
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N-Ethylmaleimide (CAS 128-53-0) is a small molecule commonly utilized in biochemical research as a selective alkylating agent for sulfhydryl groups on cysteine residues in proteins By irreversibly modifying thiol groups N-Ethylmaleimide disrupts the function of enzymes and other proteins that depend on free cysteines for activity or structural integrity This property enables researchers to investigate thiol-dependent biochemical pathways study protein conformational changes and elucidate redox regulation mechanisms Its application extends to proteomics enzymology and the analysis of intracellular signaling processes involving cysteine-mediated modifications
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Medchemexpress LLC Amino-PEG4-Val-Cit-PAB-MMAE | 1492056-71-9 | 99.9% | 1370.71 | C69H115N11O17 | 10 MG
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Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable four-unit polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis, featuring an amino-terminated PEG4 spacer, a Val-Cit cleavable dipeptide, a PAB self-immolative spacer, and the MMAE payload.
- Cleavable four-unit PEG linker suitable for ADC synthesis.
- Amino-terminated PEG4 spacer enables conjugation.
- Val-Cit dipeptide and PAB spacer allow enzymatic release of MMAE.
- High purity, 99.93%.
- Stored at -20°C, protect from moisture and light.
- Soluble in DMSO at 100 mg/mL; ultrasonic aid recommended.
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Medchemexpress LLC Bisindolylmaleimide VIII acetate | 138516-31-1 | 99.7% | 458.51 g/mol | C26H26N4O4 | 5 MG
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Bisindolylmaleimide VIII acetate is a bisindolylmaleimide derivative used as a research reagent to inhibit protein kinase C (PKC) activity in biochemical and cellular studies. It is used to probe PKC-mediated signaling and apoptosis pathways and is supplied in small milligram-scale vials for laboratory use.
- High purity of 99.7%.
- Molecular weight 458.51 g/mol.
- Molecular formula C26H26N4O4.
- Brown to reddish brown solid appearance.
- Potent inhibitor of protein kinase C and multiple PKC isoforms.
- Suitable for enzymatic and cell-based assays studying apoptosis.
- Available in small milligram vials (5 mg-50 mg).
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Cayman Chemical BIsIndolylmaleImIde V 25mg
A weak inhibitor of PKC demonstrating an IC50 value >100 µM; blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC50 value of 8 µM
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eMolecules Medchem Express / Caroverine (hydrochloride) / 10mg / 599150341 / HY-106467B / / 55750-05-5 / MFCD01684929 / 401.940 / C22H28ClN3O2
Medchem Express / Caroverine (hydrochloride) / 10mg / 599150341 / HY-106467B / / 55750-05-5 / MFCD01684929 / 401.940 / C22H28ClN3O2
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![eMolecules Broadpharm / Sulfo-Cy7 maleimide / 5mg / 374905261 / BP-23928 / 95.000 / 2183440-60-8 / [null] / 869.100 / C43H49KN4O9S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502513201.JPG-250.jpg)
eMolecules Broadpharm / Sulfo-Cy7 maleimide / 5mg / 374905261 / BP-23928 / 95.000 / 2183440-60-8 / [null] / 869.100 / C43H49KN4O9S2
Broadpharm / Sulfo-Cy7 maleimide / 5mg / 374905261 / BP-23928 / 95.000 / 2183440-60-8 / [null] / 869.100 / C43H49KN4O9S2
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Medchemexpress LLC Bisindolylmaleimide I hydrochloride | 176504-36-2 | MFCD00236429 | 98.4% | 448.94 | C25H25ClN4O2 | 5 MG
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Bisindolylmaleimide I hydrochloride is a cell-permeable, reversible protein kinase C (PKC) inhibitor that also shows activity against GSK-3. It is supplied as a powder for research and analytical use, with reported potency in the low nanomolar range against PKC isoforms and a high reported purity.
- Cell-permeable, reversible PKC inhibitor
- Potent activity: IC50 ≈ 16-20 nM for PKC isoforms
- Also reported to inhibit GSK-3
- High purity (reported 98.4%)
- Supplied as a powder in small analytical pack sizes (for example, 1 mg, 5 mg, 10 mg)
- Recommended storage: powder at 4°C or -20°C; solutions at -20°C or -80°C
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Medchemexpress LLC Bisindolylmaleimide XI hydrochloride | 145333-02-4 | MFCD01319127 | 98.0% | 489.01 g/mol | C28H29ClN4O2 | 1 MG
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Bisindolylmaleimide XI hydrochloride is a bisindolylmaleimide-class small molecule and a potent inhibitor of protein kinase C (PKC) isoforms. It is supplied as the hydrochloride salt for research use and is used in studies of PKC-dependent signaling and cellular pathways.
- Potent PKC inhibitor for biochemical and cellular studies.
- Hydrochloride salt form improves solubility for assay preparation.
- Available in small research pack sizes (1 mg, 5 mg, 10 mg).
- Molecular weight 489.01 g/mol; formula C28H29ClN4O2.
- High purity (98.0%) suitable for research applications.
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Medchemexpress LLC Crocin II | 55750-84-0 | MFCD11111454 | 98.0% | 10 MG
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Crocin II is a natural glycoside isolated from Gardenia jasminoides, supplied as a solid research reagent and analytical standard with reported antioxidant, anticancer, and antidepressant activities. The product is characterized by a molecular weight of 814.82 g/mol, CAS number 55750-84-0, and a recorded purity around 98%. Recommended storage is -20°C and protect from light; solubility in DMSO is approximately 25 mg/mL.
- Natural glycoside isolated from Gardenia jasminoides
- High purity suitable for analytical applications
- Molecular weight 814.82 g/mol and CAS 55750-84-0
- Soluble in DMSO (≈25 mg/mL) for in vitro use
- Storage recommended at -20°C and protect from light
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Medchemexpress LLC Amino-PEG4-Val-Cit-PAB-MMAE | 1492056-71-9 | 99.9% | 1370.71 g/mol | C69H115N11O17 | 25 MG
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Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4-unit polyethylene glycol (PEG) linker containing a valine-citrulline (Val-Cit) dipeptide and a para-aminobenzyl (PAB) self-immolative spacer designed for use in antibody-drug conjugate (ADC) synthesis. It provides a hydrophilic spacer, a protease-cleavable linker for controlled payload release, and an amine handle for conjugation to payloads such as MMAE. Supplied as a purified solid for research use and soluble in DMSO.
- Cleavable Val-Cit dipeptide enables protease-mediated payload release.
- PAB self-immolative spacer enables rapid payload release after cleavage.
- Four-unit PEG spacer increases hydrophilicity and solubility.
- Primary amine handle supports site-specific conjugation chemistries.
- High purity and characterized molecular weight for reproducible conjugation.
- Soluble in DMSO at 100 mg/mL for convenient stock preparation.
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Medchemexpress LLC N- t-Boc-Aminooxy-PE | 25MG
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N- t-Boc-Aminooxy-PE | 25MG
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Medchemexpress LLC Boc-aminooxy-PEG2-pr | 50MG
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Boc-aminooxy-PEG2-pr | 50MG
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Medchemexpress LLC HS-PEG6-CH2CH2-Boc | 25MG
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HS-PEG6-CH2CH2-Boc | 25MG
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Medchemexpress LLC N- Azido-PEG4 -N-Boc | 100MG
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N- Azido-PEG4 -N-Boc | 100MG
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Medchemexpress LLC (S,S,R,S,R)-Boc-Dap-NE | 3026595-14-9 | 99.8% | C23H36N2O5 | 100 MG
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This product, identified as (S,S,R,S,R)-Boc-Dap-NE, is categorized as a laboratory chemical for the manufacture of substances. It is intended for research use only and must be handled by suitably qualified and experienced scientists in appropriately equipped and authorized facilities. The product has been tested and complies with the given specifications.
- Appearance: White to off-white solid
- Chemical formula: C23H36N2O5
- Molecular weight: 420.54
- Purity: 99.78% (HPLC)
- Storage: 4°C under nitrogen; in solvent, -80°C for 6 months or -20°C for 1 month under nitrogen. Shipping at room temperature if less than 2 weeks.
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