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Filtered Search Results
Medchemexpress LLC (Rac)-Etavopivat | 2622070-93-1 | 99.9% | 457.50 | 25 MG
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(Rac)-Etavopivat, also known as (Rac)-FT-4202, is an isomer of Etavopivat. This compound acts as an orally active erythrocyte pyruvate kinase-R (PKR) activator, making it suitable for studies related to sickle cell disease and other hemoglobinopathies.
- Isomer of Etavopivat
- Orally active erythrocyte pyruvate kinase-R (PKR) activator
- Solid appearance, white to off-white color
- Can be used in studies of sickle cell disease and other hemoglobinopathies
- Improves hemoglobin-oxygen affinity and reduces the sickle point (PoS) in human red blood cells (In Vitro)
- Causes an increase in 2,3-DPG and ATP in crab-eating monkeys at doses of 8 mg/kg and 22 mg/kg (In Vivo)
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eMolecules Combi-Blocks Inc [2-(tert-Butoxycarbonylamino)-7-fluoro-1 3-benzothiazol-4-yl]boronic acid 250mg 642137992 JF-5155 98 000 2415163-55-0 312 120 C12H14BFN2O4S
Combi-Blocks Inc [2-(tert-Butoxycarbonylamino)-7-fluoro-1 3-benzothiazol-4-yl]boronic acid 250mg 642137992 JF-5155 98 000 2415163-55-0 312 120 C12H14BFN2O4S
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Medchemexpress LLC (rac)-shikonin | 54952-43-1 | MFCD00016668 | 99.0% | 288.30 g/mol | C16H16O5 | 10 MG
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(Rac)-Shikonin is the racemic form of shikonin, a naphthoquinone natural product used in research to induce necroptosis and investigate cell-death pathways. It is provided as a high-purity solid suitable for in vitro laboratory studies.
- Induces necroptotic and necrotic cell death in cancer model systems.
- Useful for studying cell-death pathways and mechanisms of drug resistance.
- High purity solid appropriate for research applications.
- Stable when stored protected from light; specific solvent storage conditions apply.
- Available in small (mg-scale) quantities for laboratory use.
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Medchemexpress LLC (Rac)-EBET-1055 | 3031540-65-2 | 97.17% | 923.02 | 5 MG
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(Rac)-EBET-1055 is the racemate of EBET-1055, a bromodomain and extra-terminal (BET) PROTAC degrader.
- Effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC).
- Simultaneously modulates cancer-associated fibroblast (CAF) activity, upregulating all reporter gene activities in organoid co-cultures.
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Medchemexpress LLC (Rac)-Apremilast | 253168-86-4 | 99.5% | 460.50 | 50 MG
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(Rac)-Apremilast ((Rac)-CC-10004) is the racemic mixture of Apremilast. It possesses anti-inflammatory properties and is utilized for research concerning inflammatory diseases, such as psoriasis.
- Racemic mixture of Apremilast.
- Exhibits anti-inflammatory properties.
- Useful for research on inflammatory diseases like psoriasis.
- Inhibits TNFalpha production in LPS-stimulated human PBMC with an IC50 of 0.19 μM.
- IC50 for hPDE4D is 0.3 nM.
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Medchemexpress LLC (Rac)-BAY1238097 | 1564268-19-4 | 99.7% | 451.56 | 100 MG
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(Rac)-BAY1238097 is a BET inhibitor that has an IC50 of 1.02 μM for BRD4 and is used in cancer research.
- Functions as a BET inhibitor
- Exhibits an IC50 of 1.02 μM for BRD4
- Utilized in cancer research
- Active in epigenetic reader domain
- Relevant for cancer and blood-related diseases
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Medchemexpress LLC (Rac)-Modipafant (UK-74505) | 122956-68-7 | 98.15% | 605.09 | 500 MG
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(Rac)-Modipafant (UK-74505) is an orally active, selective, and long-acting irreversible platelet activating factor receptor (PAFR) antagonist. It prevents dengue infection and is intended for research use only.
- Orally active
- Selective PAFR antagonist
- Long-acting irreversible PAFR antagonist
- Prevents dengue infection
- For research use only
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eMolecules (2R,4S)-1-(TERT-BUTOXYCARBONYL)-4-(DIFLUOROMETHOXY)PYRROLIDINE-2-CARBOXYLIC ACID | | MFCD30471023 | 1g
AstaTech | (2R,4S)-1-(TERT-BUTOXYCARBONYL)-4-(DIFLUOROMETHOXY)PYRROLIDINE-2-CARBOXYLIC ACID | 1g | 533784294 | 89995 | 95.000 | | MFCD30471023 | 281.256 | C11H17F2NO5
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![eMolecules Pharmablock / tert-butyl N-[[1-(aminomethyl)cyclopropyl]methyl]carbamate / 25mg / 716543992 / PBU9128 / 0.000 / 1147109-42-9 / MFCD24212994 / 200.282 / C10H20N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502459697.PNG-250.jpg)
eMolecules Pharmablock / tert-butyl N-[[1-(aminomethyl)cyclopropyl]methyl]carbamate / 25mg / 716543992 / PBU9128 / 0.000 / 1147109-42-9 / MFCD24212994 / 200.282 / C10H20N2O2
Pharmablock / tert-butyl N-[[1-(aminomethyl)cyclopropyl]methyl]carbamate / 25mg / 716543992 / PBU9128 / 0.000 / 1147109-42-9 / MFCD24212994 / 200.282 / C10H20N2O2
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![eMolecules Pharmablock / (2R3S)-1-tert-butoxycarbonyl-3-phenyl-pyrrolidine-2-carboxylic acid / 25mg / 551289472 / PBU1109 / 0.000 / 123724-32-3 / [null] / 291.347 / C16H21NO4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502444890.PNG-250.jpg)
eMolecules Pharmablock / (2R3S)-1-tert-butoxycarbonyl-3-phenyl-pyrrolidine-2-carboxylic acid / 25mg / 551289472 / PBU1109 / 0.000 / 123724-32-3 / [null] / 291.347 / C16H21NO4
Pharmablock / (2R3S)-1-tert-butoxycarbonyl-3-phenyl-pyrrolidine-2-carboxylic acid / 25mg / 551289472 / PBU1109 / 0.000 / 123724-32-3 / [null] / 291.347 / C16H21NO4
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Medchemexpress LLC BMS-1166 (hydrochloride) | 2113650-05-6 | 100.0% | 677.57 g/mol | C36H34Cl2N2O7 | 5 MG
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BMS-1166 hydrochloride is a small-molecule PD-1/PD-L1 immune checkpoint inhibitor that induces PD-L1 dimerization and blocks PD-1 binding. It exhibits potent biochemical activity in the low-nanomolar range and is supplied as a stable hydrochloride salt in solid form for research use in biochemical and cellular assays.
- Potent PD-1/PD-L1 interaction inhibitor with low-nanomolar activity.
- Hydrochloride salt, solid, white to off-white, suitable for handling.
- High purity appropriate for research applications.
- Stable as a powder under recommended storage conditions for extended shelf life.
- Intended for use in biochemical and cell-based immune checkpoint studies.
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eMolecules (S)-N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID | 150407-69-5 | MFCD07369991 | 5g
AstaTech | (S)-N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID | 5g | 268495875 | 66713 | 98.000 | 150407-69-5 | MFCD07369991 | 364.398 | C18H24N2O6
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![eMolecules AstaTech / (2S)-1-[(TERT-BUTOXY)CARBONYL]-44-DIFLUOROPIPERIDINE-2-CARBOXYLIC ACID / 0.1g / 504973269 / P20319 / 95.000 / 1221793-42-5 / MFCD03094869 / 265.257 / C11H17F2NO4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502471390.JPG-250.jpg)
eMolecules AstaTech / (2S)-1-[(TERT-BUTOXY)CARBONYL]-44-DIFLUOROPIPERIDINE-2-CARBOXYLIC ACID / 0.1g / 504973269 / P20319 / 95.000 / 1221793-42-5 / MFCD03094869 / 265.257 / C11H17F2NO4
AstaTech / (2S)-1-[(TERT-BUTOXY)CARBONYL]-44-DIFLUOROPIPERIDINE-2-CARBOXYLIC ACID / 0.1g / 504973269 / P20319 / 95.000 / 1221793-42-5 / MFCD03094869 / 265.257 / C11H17F2NO4
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Medchemexpress LLC Racemate of BL-918 | 2435589-07-2 | 98.9% | 533.44 | C23H15F8N3OS | 50MG
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Rac-BL-918 is the racemic form of BL-918, a small-molecule activator of UNC-51-like kinase 1 (ULK1) that induces cytoprotective autophagy. It is supplied for research use in solid and solution formats and is used in cellular assays investigating autophagy and neurodegenerative disease mechanisms. The product is provided with high reported purity suitable for biochemical and cell-based studies.
- Racemic small-molecule activator of UNC-51-like kinase 1 (ULK1).
- Induces cytoprotective autophagy in cellular models.
- Available as solid powder and as DMSO solutions for assay preparation.
- High reported purity suitable for research (≈98.9%).
- Used in studies of autophagy and neurodegenerative disease mechanisms.
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Medchemexpress LLC (Rac)-TTA-P2 | 918430-49-6 | 98.7% | C21H29Cl2FN2O2 | 25 MG
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(Rac)-TTA-P2 is an isomer of TTA-P2 and can be used as an experimental control. TTA-P2 is a potent inhibitor of the T-Type calcium channel. It penetrates the Central Nervous System (CNS) effectively and blocks native T-type currents in deep cerebellar nuclear neurons, completely abolishing the window current for both wild-type and mutant Cav3.1 channels. This product has potential for research into neurological diseases.
- Can be used as an experimental control
- Potent inhibitor of the T-type calcium channel
- Effectively penetrates the central nervous system (CNS)
- Blocks native T-type currents in deep cerebellar nuclear neurons
- Completely abolishes window current for both wild-type and mutant Cav3.1 channels
- Has potential for research in neurological diseases
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