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Filtered Search Results
Medchemexpress LLC (Rac)-Rotigotine hydrochloride | 102120-99-0 | C19H26ClNOS | 5 MG
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(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine, functioning as a full agonist of the dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. It is primarily utilized in research contexts, especially for studies related to Parkinson's disease.
- Functions as a full agonist at dopamine receptors
- Acts as a partial agonist at the 5-HT1A receptor
- Serves as an antagonist at the alpha-2B adrenergic receptor
- Shows selectivity for D3 receptors over D2, D4, D5, and D1 receptors
- Provides protection for dopaminergic neurons against MPP+ toxicity
- Significantly inhibits ROS production caused by rotenone
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Medchemexpress LLC S R S -AHPC-BOC DER | 25MG
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S R S -AHPC-BOC DER | 25MG
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eMolecules TERT-BUTYL N- 3R-3-METHYL 5G
5000165341 TERT-BUTYL N- 3R-3-METHYL 5G
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Cayman Chemical BIsIndolylmaleImIde I 50mg
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A highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM); competitive inhibitor for the ATP binding site of PKC; highly selective for PKCα, β1, β2, γ, δ, and ε isozymes; inhibits GSK3 in primary adipocyte lysates (IC50 = 360 nM) and in GSK3β immunoprecipitates derived from rat epididymal adipocytes (IC50 = 170 nM); competitively antagonizes the 5-HT3 receptor with a Ki value of 61 nM
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Apexbio Technology LLC Alarelin Acetate,50mg CAS# 79561-22-1
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Alarelin (Gonadotrophin-releasing hormone) is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation and is used to treat endmometriosis. Alarelin Acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland. Other sizes are also available. Please inqury us for quote.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377757 RAC -LOMEDEUCITINIB 1MG
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Biotium Thiol Reactive Dyes Reactive CF Dyes Other Dyes Biotinylation Reagents Reactive CF Dyes CF790 1/EA
CF Dye Maleimides are thiol-reactive fluorescent dyes Maleimides are commonly used to label proteins on free thiol groups CF Dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness photostability and conjugate specificity compared to other fluorescent dyes Near-IR fluorescent CF790 dye has excitation/emission at 783/808 nm
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FUJIFILM BIOSCIENCES INC 4-PHENYL-2-PYRROLIDINONE 5G
NC3785694 4-PHENYL-2-PYRROLIDINONE 5G
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Medchemexpress LLC Z-321 | 130849-58-0 | 99.7% | 344.47 | 5 MG
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Z-321 is a prolylendopeptidase (PEP) inhibitor. It has been shown to decrease the mean lordosis quotient (LQ) in treated groups. Specifically, a dose of 300 mg/kg Z-321 was effective in inhibiting lordosis behavior without disturbing locomotor activity in female rats.
- Inhibitor of prolylendopeptidase (PEP).
- Decreases sexual receptivity (mean lordosis quotient).
- Inhibits lordosis behavior without disturbing locomotor activity at 300 mg/kg.
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Medchemexpress LLC Dapagliflozin ((2S)-1,2-propanediol, hydrate) | 960404-48-2 | MFCD28167768 | 100.0% | 502.98 g·mol⁻¹ | C24H35ClO9 | 10 MG
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Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the propanediol monohydrate form of dapagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor provided for research use. It is intended for in vitro and preclinical studies of glucose transport, metabolic pathways, and pharmacology; consult the certificate of analysis and safety data sheet for handling, storage, and purity details.
- Propanediol monohydrate form for consistent solubility and handling.
- Selective SGLT2 inhibitor for studies of glucose transport and metabolism.
- High purity (99.99% HPLC) suitable for analytical and preclinical applications.
- Molecular weight 502.98 g·mol⁻¹ and formula C24H35ClO9 for accurate dosing and calculations.
- Available as small solid quantities and as concentrated solution stocks for flexible dosing.
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Medchemexpress LLC Z-val-ala-asp | 162852-62-2 | 99.8% | 437.44 | 5 MG
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Z-VAD is an irreversible, broad-spectrum pan-caspase inhibitor that can inhibit a variety of caspases. It blocks apoptosis signaling pathways, induces autophagy and necrosis in tumor cells, and exhibits anti-angiogenic activity. It can also enhance the sensitivity of breast cancer and lung cancer cells to radiotherapy in vitro and in vivo, prolonging the growth delay of tumor xenograft models. Z-VAD is well tolerated and is primarily used in research concerning cancer radiosensitization and cell death pathway regulation.
- Inhibits a variety of caspases
- Blocks apoptosis signaling pathways
- Induces autophagy and necrosis in tumor cells
- Has anti-angiogenic activity
- Enhances sensitivity of breast and lung cancer cells to radiotherapy
- Prolongs growth delay of tumor xenograft models
- Well tolerated
- Mainly used in research related to cancer radiosensitization and cell death pathway regulation
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eMolecules 1-BOC-1 2 3 6-TETRAHYDROP 500G
5000225930 1-BOC-1 2 3 6-TETRAHYDROP 500G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379872 RAC -BENPYRINE 1MG
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Medchemexpress LLC E/Z-mirin | 299953-00-7 | 99.2% | 220.25 g/mol | C10H8N2O2S | 1 ML
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E/Z-Mirin is a stereoisomeric mixture of (E)- and (Z)-mirin that inhibits the MRN (Mre11-Rad50-Nbs1) complex and prevents MRN-dependent ATM activation, used in research on DNA damage response and cell cycle signaling.
- Inhibits MRN complex and blocks MRN-dependent ATM activation
- Supplied as a 10 mM solution in DMSO and as solid quantities for flexible dosing
- High purity suitable for biochemical and cell-based assays
- Low molecular weight (220.25 g/mol) facilitates cellular studies
- SMILES provided for cheminformatics and compound registries
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Medchemexpress LLC (Rac)-EBET-1055 | 3031540-65-2 | 97.2% | 923.02 | 50 MG
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(Rac)-EBET-1055 is the racemate of EBET-1055. It is a bromodomain and extra-terminal (BET) PROTAC degrader.
- Effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC).
- Simultaneously modulates cancer-associated fibroblast (CAF) activity.
- Upregulates all reporter gene activities in organoid co-cultures.
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