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Filtered Search Results
Medchemexpress LLC Mal-C6-α-amanitin | 1578249-76-9 | 98.5% | 1211.34 | C55H78N12O17S | 5 MG
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Mal-C6-α-amanitin is an agent-linker conjugate for antibody-drug conjugates that delivers the RNA polymerase II inhibitor α-amanitin via a Mal-C6 linker. It is supplied as a solid for research use and shows potent antitumor activity in preclinical studies.
- Agent-linker conjugate for antibody-drug conjugates
- Molecular action: RNA polymerase II inhibitor
- Form: solid; color white to light yellow
- Purity: 98.5%
- Pack size: 5 mg
- Storage: -20°C, protect from light; in solvent -80°C for 6 months, -20°C for 1 month
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Chemscene CHEMSCENE
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5000578114 N- 2-HYDROXYETHYL MALEIMID 25G
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Sigma Aldrich Fine Chemicals Biosciences Rolipram | 61413-54-5 | MFCD00270906 | 10mg
Rolipram | Purity: 98% | Mol Wt: 275.34 | 61413-54-5 | MFCD00270906 | 10mg
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Sigma Aldrich Fine Chemicals Biosciences Rolipram solid, >=98% (HPLC) | 61413-54-5 | MFCD00270906 | 100MG
Rolipram solid, >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 275.34 | 61413-54-5 | MFCD00270906 | 100MG
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Medchemexpress LLC Carbonic anhydrase inhibitor 2 | 2758231-43-3 | 98.4% | C12H16N4O6S | 25 MG
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Carbonic anhydrase inhibitor 2 is described as a carbonic anhydrase II inhibitor. It has been shown to reduce intraocular pressure in glaucomatous rabbits.
- Target is CA II
- Soluble in DMSO (20 mg/mL)
- In vivo solubility protocols available with DMSO, PEG300, Tween-80, Saline, SBE-β-CD, or Corn Oil
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Medchemexpress LLC Azido-PEG24-acid | 2195075-62-6 | 99.9% | C51H101N3O26 | 50 MG
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Azido-PEG24-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules, and also in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc).
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Store stock solution at -80°C for up to 6 months.
- Store stock solution at -20°C for up to 1 month.
- Requires sealed storage, away from moisture.
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eMolecules 3-Maleimidopropionic acid | Ambeed | 7423-55-4 | MFCD00043030 | 169.136 | C7H7NO4 | 95.000 | OC(=O)CCN1C(=O)C=CC1=O | 10g | 525008566
3-Maleimidopropionic acid | Ambeed | 7423-55-4 | MFCD00043030 | 169.136 | C7H7NO4 | 95.000 | OC(=O)CCN1C(=O)C=CC1=O | 10g | 525008566
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Ambeed 1 2Hydroxyethyl 1Hpyrrole2 5di
1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione, 1585-90-6, 97%
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Medchemexpress LLC AA-T3A-C12 | 2938207-23-7 | 99.8% | 1059.72 | 100 MG
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AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid) that mediates excellent RNA delivery and transfection of activated fibroblasts. It is for research use only.
- Enhances uptake of siRNA LNP by TGF-β-stimulated 3T3 fibroblasts
- Enables robust gene knockdown in activated fibroblasts
- Significantly down-regulates HSP47 expression in fibrotic mice
- Appearance: Liquid, colorless to light yellow
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Medchemexpress LLC PMX 205 Trifluoroacetate | 99.5% | 953.06 | 50 MG
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PMX 205 Trifluoroacetate | 99.5% | 953.06 | 50 MG
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Medchemexpress LLC Br-Boc-C2-azido | 1120364-53-5 | >98% | 236.07 | 1 G
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Br-Boc-C2-azido is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. It acts as a click chemistry reagent due to its Azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Alkyl/ether-based linker for PROTAC synthesis
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Supports PROTACs in degrading target proteins via the ubiquitin-proteasome system
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Medchemexpress LLC Mal-NH-PEG8-Boc | 648.74 | 50 MG
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Mal-NH-PEG8-Boc is a laboratory chemical used for the manufacture of substances and is intended for research use only.
- Stable under recommended storage conditions
- Recommended storage at 4°C, stored under nitrogen
- Ships at room temperature for less than 2 weeks
- Appearance: oil
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000282658 N- 2-HYDROXYETHYL IM 500G
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Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.3% | 369.54 | 100 MG
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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It is a putative MAGL inhibitor that modulates the effects of 2-arachidonyl glycerol (2-AG), increasing endogenous levels of 2-AG in the brain and preventing cerebellar membrane-mediated degradation of 2-AG.
- Modulates the effects of 2-arachidonyl glycerol (2-AG)
- Increases endogenous levels of 2-AG in the brain
- Prevents cerebellar membrane-mediated degradation of 2-AG
- For research purposes only
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Sigma Aldrich Fine Chemicals Biosciences 1 Methyl 2 pyrrolidinone R
1 Methyl 2 pyrrolidinone R
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