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Filtered Search Results
Apexbio Technology LLC Z-DQMD-FMK 767287-99-0 5mg
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Z-DQMD-FMK is a small-molecule inhibitor targeting caspase-3 It is designed to selectively and irreversibly inhibit caspase-3 thereby modulating caspase-3-mediated signaling pathways and apoptotic processes Z-DQMD-FMK exerts its biological activity primarily through covalent binding to active thiol residues of caspase-3 via its fluoromethyl ketone group resulting in irreversible inhibition Based on these pharmacological properties Z-DQMD-FMK holds research potential in investigating apoptotic mechanisms caspase-3-dependent signaling and proteolytic processing events including protein kinase C isoform cleavage under zinc deficiency oxidative stress and ischemic injury
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eMolecules 1S 2S-2-FLUOROCYCLOPROPA 10G
5000163343 1S 2S-2-FLUOROCYCLOPROPA 10G
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eMolecules TERT-BUTYL N- 3R-2-OXOT 2.5G
5000163334 TERT-BUTYL N- 3R-2-OXOT 2.5G
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Medchemexpress LLC Carbonic anhydrase, Bovine erythrocytes | 9001-03-0 | 29.0 kDa | 5 MG
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Carbonic anhydrase, Bovine erythrocytes (EC 4.2.1.1) is a ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. It catalyzes the reversible conversion of carbon dioxide to bicarbonate and protons. This enzyme is primarily used for research applications in areas such as cancer, glaucoma, obesity, and epilepsy.
- Catalyzes reversible conversion of carbon dioxide to bicarbonate and protons
- Used in research for cancer, glaucoma, obesity, and epilepsy
- Zinc-containing metalloenzyme
- Optimal pH of 7.0-7.5
- Inhibitors include monovalent anions, sulfonates, sulfonamides, and imidazole
- Appears as a white to off-white solid
- Enzyme activity is ≥3000 U/mg solid
- Soluble in water at concentrations ≥ 50 mg/mL
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Medchemexpress LLC E/Z-HA155 100mg | 1229652-22-5 | 463.29 g/mol | C24H19BFNO5S | 100 MG
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(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor used as a research reagent in studies of cancer, fibrotic diseases, inflammation, pain, and angiogenesis. The compound is provided as solid and as DMSO solutions, has high reported purity, and specific storage conditions are supplied for long-term stability.
- Potent autotaxin (ATX) type I inhibitor for biochemical and cellular assays.
- High reported purity: 99.26%.
- Available in multiple quantities including 100 MG solid and 10 mM solution in DMSO.
- Chemical formula C24H19BFNO5S and molecular weight 463.29 g/mol for formulation reference.
- Storage recommendations: powder at -20°C for up to 3 years; in solvent at -80°C (6 months) or -20°C (1 month).
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Chem-Impex International, Inc. N-Boc-3-pyrrolidinone | 101385-93-7 | MFCD01631194 | 25G
N-Boc-3-pyrrolidinone, 101385-93-7, MFCD01631194, 25G
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Enzo Life Sciences Bisindolylmaleimide IV (5mg). CAS: 119139-23-0
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Alternative name: Ro 31-6233, Arcyriarubin A. Formula: C20H13N3O2. MW: 327.3. Purity: ≥95% (HPLC), single spot (TLC). Appearance: Red solid. Solubility: Soluble in DMSO or methanol. Long Term Storage: -20°C. Handling: Protect from light.
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Cayman Chemical 6 Z 9 Z 12 Z 15 Z 18 Z 21 ZTe
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A VLCPUFA; has been found in tunny, herring, cod-liver, pilot whale, sardine, and squalus-suclii-liver oils, and bovine retina; a component of triglycerides and cholesterol esters in mouse and rat testis; produced from dietary linolenic acid via a series of elongation and Δ6-desaturation reactions in fish and rat brain; undergoes β-oxidation to form DHA
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Cayman Chemical 5 Z 11 Z 14 ZEicosatrienoic A
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5(Z),11(Z),14(Z)-Eicosatrienoic acid is a PUFA found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods.{14273,14945,14947} A diet containing MPSO lowered HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro.{14273} 5(Z),11(Z),14(Z)-Eicosatrienoic acid methyl ester, when topically applied, reduces inflammatory processes, potentially by displacing arachidonic acid from phospholipid pools and reducing downstream inflammatory products such as PGE2 and LTs.{14946}
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Medchemexpress LLC BOC-(1S,3R)-3-aminocyclopentanecarboxylic acid | 261165-05-3 | 229.27 | 1 G
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BOC-(1S,3R)-3-aminocyclopentanecarboxylic acid, also known as (1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid, is a synthetic intermediate widely used in pharmaceutical synthesis.
- Used as a synthetic intermediate for pharmaceutical synthesis.
- Appears as a white to off-white solid.
- Stable for 3 years when stored at room temperature.
- Stable for 2 years at -80°C or 1 year at -20°C when stored in solvent.
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Medchemexpress LLC (Z)-Zolucatetide ((Z)-FOG-001; I-67) | 98.2% | 2076.39 | 5 MG
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(Z)-Zolucatetide is a structural isomer of Zolucatetide and acts as a potent β-catenin inhibitor with an IC50 of <50 nM. It inhibits β-catenin and T-cell factor (TCF) transcription factor interaction, suppresses cell proliferation, and induces cell cycle arrest in target cells. It has shown anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts and can be used for the study of colon cancer.
- Potent β-catenin inhibitor with an IC50 of less than 50 nM.
- Inhibits β-catenin and T-cell factor (TCF) transcription factor interaction.
- Suppresses cell proliferation.
- Induces cell cycle arrest in target cells.
- Exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell xenografts.
- Useful for the study of colon cancer.
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Medchemexpress LLC 3'-Azido-3'-deoxyuridine | 70580-88-0 | C9H11N5O5 | 5 MG
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3'-Azido-3'-deoxyuridine is a purine nucleoside analogue with broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis. This product is also a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- Purine nucleoside analogue
- Exhibits broad antitumor activity
- Inhibits DNA synthesis
- Induces apoptosis
- Click chemistry reagent with Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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eMolecules R-1-BOC-3-AMINOPYRROLIDI 25G
5000158649 R-1-BOC-3-AMINOPYRROLIDI 25G
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eMolecules BOC-SARCOSINE 5G
5000162514 BOC-SARCOSINE 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370396 RAC -M826 25MG
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