Quinolines and derivatives
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Filtered Search Results
Ambeed Methyl 6oxopiperidine2carboxyl
Methyl 6-oxopiperidine-2-carboxylate, 111479-60-8, 97%
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Medchemexpress LLC Anhydrous sodium dihydrogen phosphate, for HPLC | 7558-80-7 | 99.9% | 50 G
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Anhydrous sodium dihydrogen phosphate, for HPLC | 7558-80-7 | 99.9% | 50 G
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 50 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent and a potent, orally active, selective cytochrome P450db inhibitor. It also acts as a K+ channel blocker with an IC50 of 19.9 μM and can induce apoptosis. This product is suitable for malaria research and has shown cytotoxicity against MES-SA cells, as well as effects on the PTZ-induced seizure threshold.
- Acts as an antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- Functions as a K+ channel blocker
- Capable of inducing apoptosis
- Applicable for malaria research
- Exhibits cytotoxicity against MES-SA cells
- Affects PTZ-induced seizure threshold
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Medchemexpress LLC Heptadecan-9-amine (9-aminoheptadecane) | 3241-20-1 | MFCD30742905 | 255.48 g/mol | C17H37N | 25 G
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Heptadecan-9-amine (9-aminoheptadecane) is a primary C17 alkylamine used as an intermediate and reagent in organic synthesis and biochemical research. It is a colorless liquid with molecular formula C17H37N and molecular weight 255.48 g/mol.
- Primary C17 alkylamine for use as a chemical building block.
- Suitable for organic and medicinal chemistry applications.
- Colorless liquid appearance, suitable for solution-phase handling.
- CAS number 3241-20-1 for unambiguous identification.
- Available in laboratory pack sizes, including 25 G.
- Store at 4°C protected from light; in solvent, store at -80°C for long-term stability.
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Ambeed 1R 2R Cyclohexane1 2diamine
(1R,2R)-Cyclohexane-1,2-diamine, 20439-47-8, 96%
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Medchemexpress LLC CFDA-SE | 150347-59-4 | 98.2% | 200 MG
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CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It reacts with the free amine group in cytoskeleton proteins inside the cell, forming a protein complex with fluorescence. After entering the cell, CFDA-SE is found in the cell membrane, cytoplasm, and nucleus, with the strongest fluorescence staining observed in the nucleus. The CFDA-SE dye is uniformly inherited by cells during cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under 488 nm excitation light, making it suitable for detecting cell proliferation.
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Chemscene CHEMSCENE
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5000578387 N-BENZYLNAPHTHALEN-2-AMINE 10G
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Ambeed 4 4 Bipyridine
4,4'-Bipyridine, 553-26-4, 98%
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Medchemexpress LLC 3,6,9,12,15,18-Hexaoxanonadecan-1-amine | 184357-46-8 | ≥97.0% | 295.37 | C13H29NO6 | 250 MG
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m-PEG6-Amine (3,6,9,12,15,18-Hexaoxanonadecan-1-amine, CAS 184357-46-8) is a methoxy-terminated polyethylene glycol (PEG6) primary amine linker used as a flexible, hydrophilic spacer for assembling PROTAC molecules and as a cleavable linker in antibody-drug conjugates (ADCs). The compound has formula C13H29NO6, molecular weight 295.37, and typical purity ≥97.0%.
- Provides a six-unit polyethylene glycol spacer to improve solubility and flexibility.
- Terminal primary amine enables straightforward conjugation chemistry for amide or carbamate coupling.
- Suitable for PROTAC and ADC synthesis as a cleavable, hydrophilic linker.
- High reported purity (≥97.0%) suitable for research applications.
- Recommended storage: 4°C protected from light; in solvent, store at -80°C (6 months) or -20°C (1 month) when protected from light.
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TARGETMOL CHEMICALS INC JH-RE-06 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POL(zeta). JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 uM; Kd=0.42 uM) which targets REV1 that interacts with the REV7 subunit of POL(zeta). JH-RE-06 also improves chemotherapy. purity: 99%
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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 50 MG
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ACT-1004-1239 is a potent, selective, and orally active CXCR7 antagonist with an IC50 value of 3.2 nM. It promotes oligodendrocyte precursor cell (OPC) differentiation by increasing CXCL12 levels. In animal models, it has been shown to reduce disease severity in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) and increase myelination in Cuprizone-induced demyelination models. This product is for research use only.
- Potent, selective, and orally active CXCR7 antagonist
- IC50 value of 3.2 nM
- Promotes oligodendrocyte precursor cell (OPC) differentiation
- Increases CXCL12 levels
- Reduces disease severity in MOG-induced experimental autoimmune encephalomyelitis (EAE) in animal models
- Increases myelination in Cuprizone-induced demyelination models
- For research use only
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Medchemexpress LLC Mal-amido-PEG12-acid | 2378428-27-2 | C34H60N2O17 | 50 MG
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Mal-amido-PEG12-acid is a PEG-based PROTAC linker suitable for synthesizing PROTACs. It functions by connecting two distinct ligands, one targeting an E3 ubiquitin ligase and the other for the specific target protein, allowing for the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Can be used in the synthesis of PROTACs.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000570682 HYPERCHROM-Q-HP-AGAROSE-25ML
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Ambeed 1 3 4Oxadiazol2amine
1,3,4-Oxadiazol-2-amine, 3775-60-8, 95%
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Ambeed 2 2 Bis diphenylphosphino 1 1
2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl, 98327-87-8, 97%
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