Quinolines and derivatives
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Filtered Search Results
Chemscene ChemScene | 2-Aminoquinoline | 10G | CS-W007524 | 0.98 | 580-22-3| MFCD00038079 | 144.18
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ChemScene | 2-Aminoquinoline | 10G | CS-W007524 | 0.98 | 580-22-3| MFCD00038079 | 144.18
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Cayman Chemical allcis4 7 10 13 16Docosapenta
An ω-6 isomer of docosapentaenoic acid formed by the elongation and desaturation of arachidonic acid; diminished during fatty acid desaturase syndrome and increased in non-alcoholic steatohepatitis
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Medchemexpress LLC Lomitapide | 182431-12-5 | 99.6% | 693.72 | 200 MG
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Lomitapide is a potent inhibitor of microsomal triglyceride-transfer protein (MTP) with an IC50 of 8 nM in vitro. Intended for research use only, it undergoes hepatic metabolism via cytochrome P-450 (CYP) isoenzyme 3A4 and interacts with CYP3A4 substrates. It has been shown to reduce plasma concentrations of low-density lipoprotein cholesterol (LDL-C) by more than 50%.
- Target: microsomal triglyceride-transfer protein (MTP)
- IC50: 8 nM (MTP) in vitro
- Metabolism: hepatic metabolism via cytochrome P-450 (CYP) isoenzyme 3A4
- Bioavailability: 7.1% for the 50-mg capsule
- Half-life: 39.7 hours
- Appearance: white to off-white solid
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solvent storage: -80°C for 2 years, -20°C for 1 year
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Medchemexpress LLC SBI-553 | 1849603-72-0 | 99.7% | 450.55 | 10 MG
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SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM. It induces β-blocking protein recruitment and NTSR1 internalization without stimulating Gq protein activation, IP3 production, or calcium mobilization. In vivo, it alleviates cocaine- or methamphetamine-induced hyperactivity in wild-type mice. This product is for research use only.
- Potent and brain penetrant NTR1 allosteric modulator with an EC50 of 0.34 μM
- Induces β-blocking protein recruitment and NTSR1 internalization
- Does not stimulate Gq protein activation, IP3 production, or calcium mobilization
- Alleviates cocaine- or methamphetamine-induced hyperactivity in wild-type mice
- For research use only
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Medchemexpress LLC Dd-03-171 | 2366132-45-6 | 98.7% | 25MG
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Dd-03-171 | 2366132-45-6 | 98.7% | 25MG
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TARGETMOL CHEMICALS INC Tacedinaline 200MG
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Also available in 1 mL, 10 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity. Purity 98.37%
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eMolecules 7-HYDROXYQUINOLINE-6-CAR 0.25G
5000225524 7-HYDROXYQUINOLINE-6-CAR 0.25G
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Apexbio Technology LLC 4-quinolinol 611-36-9 500mg
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4-Quinolinol (CAS 611-36-9) is a hydroxylated derivative of quinoline with demonstrated antimicrobial properties It exerts inhibitory effects on the growth of various intestinal bacteria suggesting interference with microbial viability or metabolic pathways Additionally 4-quinolinol has been utilized in research as a sacrificial scavenger for photogenerated reactive oxygen species supporting studies on oxidative stress and photochemical processes These features highlight its utility in microbiological research and investigations into oxidative mechanisms
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Medchemexpress LLC Resmetirom | 920509-32-6 | 99.9% | 200MG
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Resmetirom | 920509-32-6 | 99.9% | 200MG
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Medchemexpress LLC 6,8-Diprenylorobol | 66777-70-6 | 1 MG
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6,8-Diprenylorobol is a prenylated isoflavone isolated from the leaves of *Cudrania tricuspidata*. It exhibits an antiproliferative effect and induces apoptosis by activating p53 and generating reactive oxygen species (ROS). It has shown to inhibit proliferation in LoVo and HCT15 cells in a dose- and time-dependent manner and also regulates MAPKs.
- Exhibits antiproliferative effect
- Induces apoptosis by activating p53
- Generates reactive oxygen species (ROS)
- Inhibits proliferation in LoVo and HCT15 cells
- Regulates MAPKs in LoVo and HCT15 cells
- Increases ROS levels in LoVo and HCT15 cells
- Inhibits LPS-induced nitric oxide production in RAW264.7 cells
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eMolecules Medchem Express / NK-252 / 5mg / 446270198 / HY-19734 / / 1414963-82-8 / MFCD28009512 / 285.263 / C13H11N5O3
Medchem Express / NK-252 / 5mg / 446270198 / HY-19734 / / 1414963-82-8 / MFCD28009512 / 285.263 / C13H11N5O3
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Medchemexpress LLC Paeoniflorin | 23180-57-6 | 98.9% | 480.46 | 200 MG
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Paeoniflorin is a heat shock protein-inducing compound commonly found in plants of the Paeoniaceae family. It exhibits diverse biological activities, making it suitable for various research applications.
- Exhibits anticancer activity
- Has anti-inflammatory properties
- Enhances cognition and attenuates learning impairment
- Provides anti-oxidative stress benefits
- Prevents antiplatelet aggregation
- Expands blood vessels
- Reduces blood viscosity
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Medchemexpress LLC Amino-PEG12-amine | 361543-12-6 | HY-133327 | 99.9% | 588.73 | 250 MG
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Amino-PEG12-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules with two different ligands connected by a linker: one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Enables synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Appears as a colorless to off-white solid-liquid mixture
- Has a purity of 99.92%
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Medchemexpress LLC 4',7-Dimethoxyisoflavone | 1157-39-7 | 10 MM 1 ML
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4',7-Dimethoxyisoflavone, also known as Dimethoxydaidzein, is a natural compound isolated from the leaves of Albizzia lebbeck. It exhibits antifungal activity against various plant pathogenic fungi and is intended for research use only.
- Isolated from Albizzia lebbeck
- Exhibits antifungal activity
- For research use only
- High purity (98.20%)
- White to off-white solid appearance
- Soluble in DMSO
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Selleck Chemical LLC FLI-06
FLI-06 is a novel inhibitor of Notch signaling with EC50 of 2 3 M
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