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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Acridine Mutagen ICR 191 | 17070-45-0 | MFCD00013320 | 10MG
Acridine Mutagen ICR 191 | Mol Wt: 451.22 | 17070-45-0 | MFCD00013320 | 10MG
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Apexbio Technology LLC Q-VD-OPh 1135695-98-5 25mg
Q-VD-OPh is a pan-caspase inhibitor targeting caspases including 1 3 8 and 9 with IC50 values ranging from approximately 25 to 400 nM By blocking multiple caspase-mediated apoptotic pathways including caspase-9/3 caspase-8/10 and caspase-12 pathways Q-VD-OPh prevents apoptotic cell death induced by agents such as actinomycin D In research contexts this inhibitor serves as a tool to investigate apoptosis mechanisms across diverse cell types and species including human mouse and rat It is also used to enhance cell viability upon thawing from cryopreservation under standard cryoprotectant conditions
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Medchemexpress LLC 7PPD-Q | 2894124-00-4 | 98.9% | 312.41 | 5 MG
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7PPD-Q is a substituted p-phenylenediamine antioxidants derivative. It has been observed to be toxic to the bacterium V. fischeri (EC50 = 14.9 mg/L).
- For research use only.
- Not sold to patients.
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Medchemexpress LLC Q-VD-OPh | 1135695-98-5 | MFCD08669741 | 99.9% | 513.49 g/mol | C26H25F2N3O6 | 10MM 1ML
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Q-VD-OPh is an irreversible pan-caspase inhibitor used in research to block apoptosis. It inhibits caspase-7 with an IC50 of approximately 48 nM and shows inhibitory activity against multiple caspases (IC50 25-400 nM). The compound is cell-permeable, reported to cross the blood-brain barrier, and is provided as powder and as DMSO stock solutions for convenient preparation of working concentrations.
- Irreversible pan-caspase inhibitor with low-nanomolar potency against caspase-7.
- Activity against multiple caspases (IC50 range 25-400 nM).
- Cell-permeable and reported to cross the blood-brain barrier.
- Available as powder or pre-prepared DMSO stock for flexible use.
- High purity suitable for research applications (reported 99.9%).
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Selleck Chemical LLC Tertiapin-Q-E0016-25MG
Tertiapin-Q (TPNQ) is a derivative of tertiapin and inhibits BK-type K channels in a use- and concentration-dependent manner Tertiapin-Q also binds to ROMK1 (Kir1 1) and GIRK1/4 (Kir3 1/3 4) channels with Ki values of 1 3 nM and 13 3 nM respectively
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Apexbio Technology LLC HyperTrap Q FF Column 5x1ml
The HyperTrap Q FF Column is not a small molecule but a chromatography medium designed for the purification of biomolecules particularly proteins and nucleic acids It operates via strong anion exchange chromatography utilizing quaternary ammonium functional groups immobilized on a Fast Flow resin matrix to selectively bind negatively charged molecules under defined buffer conditions This allows for efficient separation and recovery of target biomolecules from complex mixtures The HyperTrap Q FF Column is applied in research settings for desalting buffer exchange and isolation of nucleic acids or proteins supporting downstream analyses and preparative workflows in the biomedical field
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![Aobchem 1-[3-Fluoro-4-(4 4 5 5-tetramethyl-1 3 2-dioxaborolan-2-yl)phenyl]-1H-pyrrole | 97% | CAS 2223054-10-0 | C16H19BFNO2 | 5g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Aobchem 1-[3-Fluoro-4-(4 4 5 5-tetramethyl-1 3 2-dioxaborolan-2-yl)phenyl]-1H-pyrrole | 97% | CAS 2223054-10-0 | C16H19BFNO2 | 5g
1-[3-Fluoro-4-(4 4 5 5-tetramethyl-1 3 2-dioxaborolan-2-yl)phenyl]-1H-pyrrole | 97% | CAS 2223054-10-0 | C16H19BFNO2 | 5g
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Aobchem 4-Fluoro-5-isopropoxy-2-methylbenzoic acid | 97% | CAS 2901095-48-3 | C11H13FO3 | 10g
4-Fluoro-5-isopropoxy-2-methylbenzoic acid | 97% | CAS 2901095-48-3 | C11H13FO3 | 10g
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Aobchem 5-Fluoro-8-methylquinoline | ≥97% | CAS 88474-18-4 | C10H8FN | 5g
5-Fluoro-8-methylquinoline | ≥97% | CAS 88474-18-4 | C10H8FN | 5g
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Aobchem 4-Fluoro-2-isopropoxy-5-methylphenylboronic acid | ≥97% | CAS 2096336-36-4 | C10H14BFO3 | 5g
4-Fluoro-2-isopropoxy-5-methylphenylboronic acid | ≥97% | CAS 2096336-36-4 | C10H14BFO3 | 5g
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![Aobchem [3-Fluoro-4-(methylsulfanyl)phenyl]methanol | ≥97% | CAS 252562-45-1 | C8H9FOS | 250mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000991462.png-250.jpg)
Aobchem [3-Fluoro-4-(methylsulfanyl)phenyl]methanol | ≥97% | CAS 252562-45-1 | C8H9FOS | 250mg
[3-Fluoro-4-(methylsulfanyl)phenyl]methanol | ≥97% | CAS 252562-45-1 | C8H9FOS | 250mg
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Aobchem 2 4-Dichloro-3-methylquinoline | ≥97% | CAS 56857-97-7 | C10H7Cl2N | 1g
2 4-Dichloro-3-methylquinoline | ≥97% | CAS 56857-97-7 | C10H7Cl2N | 1g
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Medchemexpress LLC 6PPD-quinone | 2754428-18-5 | 99.3% | 298.38 g/mol | C18H22N2O2 | 10 MG
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6PPD-quinone is an oxidized derivative of the tire antioxidant 6-PPD, supplied as a high-purity research reagent for environmental and toxicological studies. It is commonly used as a reference standard for analytical method development, quantification in environmental matrices, and mechanistic investigations of toxicity.
- High purity (99.3%).
- CAS number 2754428-18-5 for unambiguous identification.
- Suitable as an analytical reference standard for LC and GC methods.
- Intended for environmental and toxicological research applications.
- Available in milligram pack sizes for laboratory use.
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![eMolecules 91301-03-0 | 2-Oxo-1,2-dihydro-3-quinolinecarbaldehyde | Combi-Blocks | MFCD00563443 | 173.171 | C10H7NO2 | 95.000 | O=Cc1cc2ccccc2[nH]c1=O | 1g | 517031583](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183721.JPG-250.jpg)
eMolecules 91301-03-0 | 2-Oxo-1,2-dihydro-3-quinolinecarbaldehyde | Combi-Blocks | MFCD00563443 | 173.171 | C10H7NO2 | 95.000 | O=Cc1cc2ccccc2[nH]c1=O | 1g | 517031583
2-Oxo-1,2-dihydro-3-quinolinecarbaldehyde | Combi-Blocks | 91301-03-0 | MFCD00563443 | 173.171 | C10H7NO2 | 95.000 | O=Cc1cc2ccccc2[nH]c1=O | 1g | 517031583
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Medchemexpress LLC 6PPD-Q | 2754428-18-5 | C18H22N2O2 | 25 MG
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6PPD-Q (6PPD-Quinone) is an environmental pollutant detected in human urine and widely present in the environment. It targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 showing the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. It can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. This compound is applicable for research in environmental toxicology, neurodegenerative diseases, and inflammation-related disorders.
- Targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1
- Acts as a CNR2 receptor agonist
- Induces intestinal inflammation and barrier damage
- Reduces neuronal glycolysis metabolites and TCA cycle intermediates
- Exacerbates α-synuclein (α-syn) aggregation
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