Quinolines and derivatives
Medchemexpress LLC Dbco-amine (Gmp) | 1255942-06-3 | 276.33 | 500 MG
DBCO-amine (GMP) is a GMP grade click chemistry reagent that contains a DBCO group. This group enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that possess azide groups. It is utilized in the synthesis of antibody-drug conjugates (ADCs).
- Gmp grade
- Click chemistry reagent
- Contains a DBCO group for SPAAC reactions
- Used in the synthesis of antibody-drug conjugates (ADCs)
eMolecules 1823775-69-4 | METHYL 2-AMINOQUINOLINE-6-CARBOXYLATE | AstaTech | MFCD28050543 | 202.213 | C11H10N2O2 | 95.000 | COC(=O)c1ccc2nc(N)ccc2c1 | 0.25g | 410713923
METHYL 2-AMINOQUINOLINE-6-CARBOXYLATE | AstaTech | 1823775-69-4 | MFCD28050543 | 202.213 | C11H10N2O2 | 95.000 | COC(=O)c1ccc2nc(N)ccc2c1 | 0.25g | 410713923
eMolecules 58794-09-5 | 7-bromoisoquinoline | Pharmablock | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 10g | 551259465
7-bromoisoquinoline | Pharmablock | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 10g | 551259465
Medchemexpress LLC Mpeg-amine (mw 5000) | 80506-64-5 | 99.6% | (C2H4O)nC3H9NO | 100 MG
mPEG-amine (mPEG-NH2) (MW 5000) is a modifier used to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes by replacing their sulfonic acid portion. It can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS.
- Increases water solubility of dyes
- Forms amide bonds with carboxyl groups
- Suitable for large-scale rotational cytoplasmic flow studies
Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | ≥97.0% | C22H46N4O10 | 250 MG
Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker for PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- PROTACs degrade target proteins via the ubiquitin-proteasome system
- Appearance is colorless to off-white
Medchemexpress LLC 7-bromoquinoline-4-carboxylic acid | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 | C10H6BrNO2 | 500 MG
7-Bromoquinoline-4-carboxylic acid is an organic small-molecule reagent used primarily as an intermediate in synthetic chemistry and for biochemical assay research. It is a brominated quinoline carboxylic acid commonly employed to build substituted heterocycles and as a starting material for structure-activity studies.
- Used as an intermediate in chemical synthesis and biochemical research.
- Molecular formula C10H6BrNO2 and molecular weight 252.06 g·mol-1.
- CAS number 31009-04-8 for unambiguous identification.
- Typical purity 96.1% (HPLC) as reported on the certificate of analysis.
- Appearance: gray to brown solid.
- Recommended storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Isoquinolin-4-amine | 23687-25-4 | 144.17 | 10 G
Isoquinolin-4-amine is a biochemical reagent used as a biological material or organic compound for life science-related research. It is intended for research use only.
- Can be used as a biological material
- Can be used as an organic compound
- Suitable for life science-related research
Selleck Chemical LLC JNK-IN-8 S4901-1g
JNK-IN-8 (JNK Inhibitor XVI) is the first irreversible JNK inhibitor for JNK1 JNK2 and JNK3 with IC50 of 4 7 nM 18 7 nM and 1 nM 10-fold selectivity against MNK2 Fms and no inhibition to c-Kit Met PDGFR in A375 cell line