Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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646 – 660 of 4,235 results

646

eMolecules 103476-89-7 | Leupeptin Hemisulfate | Target Molecule951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 25mg | 448758926

Leupeptin Hemisulfate | Target Molecule | 103476-89-7951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 25mg | 448758926

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647

Medchemexpress LLC Lobeglitazone (sulfate) | 763108-62-9 | 99.6% | 578.61 | 50 MG

Lobeglitazone sulfate is a new type of thiazolidinedione and an orally active agonist for PPAR with EC50 of 137.4 nM and 546.3 nM for PPARγ and PPARα. It is an inhibitor for the ERK/JNK/Smad/NF-κB signaling pathway and exhibits anti-inflammatory, anti-diabetic, anti-fibrotic, and anti-atherosclerotic properties.

Orally active agonist for PPAR.
Inhibits the ERK/JNK/Smad/NF-κB signaling pathway.
Exhibits anti-inflammatory properties.
Possesses anti-diabetic properties.
Demonstrates anti-fibrotic and anti-atherosclerotic properties.

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648

Medchemexpress LLC 8-Hydroxyquinoline hemisulfate (Standard) | 134-31-6 | 99.6% | 194.20 | 25 MG

8-Hydroxyquinoline hemisulfate (Standard) is an analytical standard and monoprotic bidentate chelating agent. It is intended for research and analytical applications, commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.

Functions as a transcription inhibitor
Exhibits antiseptic properties
Displays disinfectant properties
Acts as a pesticide

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649

Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 50 MG

5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. It can inhibit NF-κB activity and induce cancer cell death, while exhibiting low cytotoxicity towards normal hematopoietic cells. This compound is utilized for cancer research, particularly in studies related to leukemia.

Orally active non-competitive 20S proteasome inhibitor
Inhibits NF-κB activity
Induces cancer cell death
Low cytotoxicity towards normal hematopoietic cells
Suitable for cancer research, including leukemia studies

Pricing & Availability

650

eMolecules 202595-32-2 | ETHYL 7-HYDROXYQUINOLINE-3-CARBOXYLATE | MFCD18416643 | 1g

Ambeed | 4-Amino-5-(pyridin-4-yl)-4H-124-triazole-3-thiol | 250mg | 600844929 | A650781 | 36209-51-5 | MFCD00274215 | 193.230 | C7H7N5S

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

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651

Medchemexpress LLC Mhi-148 (ir-808) | 172971-76-5 | 98.4% | 764.23 | 50 MG

MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. It is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells.

Near-infrared heptamethine cyanine dye
Tumor-targeting properties
Used for cancer detection, diagnosis, and research
Selectively accumulates in lysosomes and mitochondria of tumor cells
Negligible toxicity in both tumor and normal cells at certain concentrations

Pricing & Availability

652

Medchemexpress LLC 8-Quinolinol, sulfate (2:1) | 134-31-6 | 99.96% | 194.20 | 1 G

8-Hydroxyquinoline hemisulfate is a monoprotic bidentate chelating agent. It exhibits antiseptic, disinfectant, and pesticide properties, and functions as a transcription inhibitor.

Monoprotic bidentate chelating agent
Antiseptic properties
Disinfectant properties
Pesticide properties
Functions as a transcription inhibitor

Pricing & Availability

653

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 50 MG

MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor with high binding affinity against MDM2 (Kd=8.2 nM) and has antitumor activity.

Potent MDM2-p53 protein-protein interaction (PPI) inhibitor
High binding affinity against MDM2 (Kd=8.2 nM)
Antitumor activity
Available in solid and solution forms
Soluble in DMSO (≥ 53 mg/mL)

Pricing & Availability

654

Medchemexpress LLC BAY-826 | 1448316-08-2 | 99.9% | 558.53 | C26H19F5N6OS | 100 MG

BAY-826 is a selective, potent small-molecule inhibitor of the TIE-2 (TEK) receptor tyrosine kinase developed as a research chemical probe. It exhibits strong binding affinity to TIE-2 (reported Kd ≈ 1.6 nM) and has demonstrated in vitro inhibition of TIE-2 autophosphorylation and in vivo efficacy in preclinical murine glioma models. For research use only; not for human therapeutic use.

Potent TIE-2 inhibition (Kd ≈ 1.6 nM).
Demonstrated in vivo efficacy in murine glioma models.
Suitable for in vitro and in vivo preclinical studies.
High chemical purity for pharmacology experiments.
Chemical formula C26H19F5N6OS and molecular weight 558.53 g·mol-1.

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655

Apexbio Technology LLC RU.521 2262452-06-0 10mg

RU 521 (CAS 2262452-06-0) is a selective inhibitor of cyclic GMP-AMP synthase (cGAS) an enzyme responsible for synthesizing cGAMP upon recognition of cytosolic double-stranded DNA By interfering with cGAS-mediated cGAMP production RU 521 suppresses activation of the type I interferon signaling pathway Experimental studies demonstrate that RU 521 reduces cGAS-dependent signal transduction and interferon responses in reporter assays containing double-stranded DNA In macrophages derived from Aicardi-Gouti res syndrome mouse models RU 521 lowers basal interferon expression This compound is a valuable tool for investigating cGAS-dependent innate immune pathways

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656

Medchemexpress LLC 2-Hydroxyquinoline | 59-31-4 | 145.16 | 1 ML

2-Hydroxyquinoline is an off-white to light yellow solid. It acts as an inhibitor of α-glucosidase and α-amylase, with IC50 values of 64.4 µg/mL and 130.5 µg/mL respectively. This product is suitable for research in the study of diabetes.

Inhibits α-glucosidase and α-amylase
Targeted to glycosidase and amylases
In vitro solubility in DMSO at 100 mg/mL
Storage conditions for powder: -20°C for 3 years, 4°C for 2 years
Storage conditions in solvent: -80°C for 6 months, -20°C for 1 month
Purity by HPLC is 99.4%
1H NMR spectrum consistent with structure

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657

Medchemexpress LLC 5-Hydroxyquinoline | 578-67-6 | 99.5% | 145.16 | 25 G

5-Hydroxyquinoline is an organic compound used in various chemical reactions and biological research. It finds application in the manufacture of dyes, cellulase, oxidants, and passivators, and is extensively utilized in the pigment, paint, and rubber industries. Additionally, it serves as a precursor, intermediate, and metal ion complexing agent for certain drugs, and is a biochemical reagent for life science-related research.

Used in the manufacture of dyes, cellulase, oxidants, and passivators
Extensively utilized in the pigment, paint, and rubber industries
Serves as a precursor, intermediate, and metal ion complexing agent for drugs
Biochemical reagent for life science-related research

Pricing & Availability

658

eMolecules 207728-71-0 | 8-Hydroxyquinoline-beta-D-glucuronic acid, sodium salt | Apollo Scientific | MFCD02683911 | 343.267 | C15H14NNaO7 | 0.000 | [Na+].O[C@@H]1[C@@H](O)[C@H](Oc2cccc3cccnc23)O[C@@H]([C@H]1O)C([O-])=O | 1g | 562462588

8-Hydroxyquinoline-beta-D-glucuronic acid, sodium salt | Apollo Scientific | 207728-71-0 | MFCD02683911 | 343.267 | C15H14NNaO7 | 0.000 | [Na+].O[C@@H]1[C@@H](O)[C@H](Oc2cccc3cccnc23)O[C@@H]([C@H]1O)C([O-])=O | 1g | 562462588

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659

Medchemexpress LLC 8-Hydroxyquinoline hemisulfate (Standard) | 134-31-6 | 99.6% | 194.20 | 10 MG

8-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.

The compound is the grade of analytical standard, which is the reference standard supplied assay.
It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Pricing & Availability

660

Medchemexpress LLC 2-quinolinecarboxaldehyde, 8-hydroxy- | 14510-06-6 | MFCD00168962 | 98.0% | 173.17 g/mol | C10H7NO2 | 1 G

8-Hydroxyquinoline-2-carbaldehyde is an organic biochemical reagent (C10H7NO2, MW 173.17 g/mol) used as a building block in organic synthesis and as a ligand in coordination and analytical chemistry. It is supplied as a solid powder in laboratory pack sizes for research applications, with batch-specific certificates of analysis available for quality confirmation.

Acts as a building block for organic synthesis.
Functions as a bidentate ligand and chelating agent.
Suitable for analytical and proteomics applications.
Provided in small pack sizes appropriate for laboratory research.
Batch-specific certificate of analysis available for purity verification.

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Quinolines and derivatives

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Medchemexpress LLC Lobeglitazone (sulfate) | 763108-62-9 | 99.6% | 578.61 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 8-Hydroxyquinoline hemisulfate (Standard) | 134-31-6 | 99.6% | 194.20 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mhi-148 (ir-808) | 172971-76-5 | 98.4% | 764.23 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 8-Quinolinol, sulfate (2:1) | 134-31-6 | 99.96% | 194.20 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BAY-826 | 1448316-08-2 | 99.9% | 558.53 | C26H19F5N6OS | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC RU.521 2262452-06-0 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Hydroxyquinoline | 59-31-4 | 145.16 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-Hydroxyquinoline | 578-67-6 | 99.5% | 145.16 | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 8-Hydroxyquinoline hemisulfate (Standard) | 134-31-6 | 99.6% | 194.20 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-quinolinecarboxaldehyde, 8-hydroxy- | 14510-06-6 | MFCD00168962 | 98.0% | 173.17 g/mol | C10H7NO2 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More