Quinolines and derivatives
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Filtered Search Results
eMolecules 82121-05-9 | 7-Methoxy-4(1H)-quinolinone | Chem-Impex | MFCD11501414 | 175.187 | C10H9NO2 | 98.000 | COc1ccc2c(c1)[nH]ccc2=O | 1g | 112750550
7-Methoxy-4(1H)-quinolinone | Chem-Impex | 82121-05-9 | MFCD11501414 | 175.187 | C10H9NO2 | 98.000 | COc1ccc2c(c1)[nH]ccc2=O | 1g | 112750550
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000429818 VARI FLUOR 532 CARBO 5MG
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eMolecules 90905-32-1 | 2-Methoxypyrimidine-5-carbaldehyde | Synthonix - Stock | MFCD03446732 | 138.126 | C6H6N2O2 | 97.000 | COc1ncc(C=O)cn1 | 5g | 483373818
2-Methoxypyrimidine-5-carbaldehyde | Synthonix - Stock | 90905-32-1 | MFCD03446732 | 138.126 | C6H6N2O2 | 97.000 | COc1ncc(C=O)cn1 | 5g | 483373818
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eMolecules 898747-24-5 | 5-Bromo-1H-indazole-7-carboxylic acid methyl ester | J & W PharmLab LLC | MFCD08458991 | 255.071 | C9H7BrN2O2 | 96.000 | COC(=O)c1cc(Br)cc2cn[nH]c12 | 5g | 289352063
5-Bromo-1H-indazole-7-carboxylic acid methyl ester | J & W PharmLab LLC | 898747-24-5 | MFCD08458991 | 255.071 | C9H7BrN2O2 | 96.000 | COC(=O)c1cc(Br)cc2cn[nH]c12 | 5g | 289352063
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Medchemexpress LLC 2'-Azido-2'-deoxycytidine | 51034-68-5 | MFCD00043047 | C9H12N6O4 | 200 MG
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2'-Azido-2'-deoxycytidine is a purine nucleoside analogue with broad antitumor activity, especially against indolent lymphoid malignancies. Its anticancer mechanisms include inhibiting DNA synthesis and inducing apoptosis. It also functions as a click chemistry reagent, capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This azidonucleoside requires diphosphorylation to inhibit nucleotide reductase.
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis and induces apoptosis
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Requires diphosphorylation for nucleotide reductase inhibition
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Medchemexpress LLC Deucravacitinib | 1609392-27-9 | 99.9% | 425.46 | 200 MG
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Deucravacitinib is a highly selective, orally bioavailable allosteric TYK2 inhibitor designed for the treatment of autoimmune diseases. It works by selectively binding to the TYK2 pseudokinase (JH2) domain, which blocks receptor-mediated Tyk2 activation by stabilizing its regulatory JH2 domain. This action inhibits IL-12/23 and type I IFN pathways. It is used for studying moderate to severe plaque psoriasis.
- Highly selective, orally bioavailable allosteric TYK2 inhibitor
- Designed for the treatment of autoimmune diseases
- Selectively binds to the TYK2 pseudokinase (JH2) domain
- Blocks receptor-mediated Tyk2 activation
- Inhibits IL-12/23 and type I IFN pathways
- Used for studying moderate to severe plaque psoriasis
- FDA's first de novo deuterium
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Medchemexpress LLC GW 4064 | 278779-30-9 | 99.8% | 542.84 | 200 MG
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GW 4064 is a potent Farnesoid X Receptor (FXR) agonist with an EC50 of 65 nM.
- Reduces lipid accumulation in cells and represses oleic acid-induced CD36 protein levels, potentially preventing hepatic lipid accumulation.
- Suppresses weight gain and significantly represses diet-induced hepatic steatosis by lowering triglyceride and free fatty acid levels in the liver.
- Markedly reduces lipid transporter CD36 expression without affecting genes directly involved in lipogenesis.
- Attenuates hepatic inflammation.
- Leads to statistically significant reductions in serum activities of ALT, AST, LDH, and ALP, as well as reduced serum bile acid levels, suggesting hepatoprotective benefits.
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eMolecules 68986-76-5 | Copper(i) thiophene-2-carboxylate | Combi-Blocks | MFCD02183524 | 190.680 | C5H3CuO2S | 95.000 | [Cu+].[O-]C(=O)c1cccs1 | 5g | 303332493
Copper(i) thiophene-2-carboxylate | Combi-Blocks | 68986-76-5 | MFCD02183524 | 190.680 | C5H3CuO2S | 95.000 | [Cu+].[O-]C(=O)c1cccs1 | 5g | 303332493
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TARGETMOL CHEMICALS INC Tandutinib 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50 0.22 uM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR. Purity 99.74%
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TARGETMOL CHEMICALS INC Ezetimibe 200MG
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Also available in 1 g, 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Ezetimibe (SCH 58235) is a dietary cholesterol absorption inhibitor that exerts its physiologic effect by decreasing cholesterol absorption. Purity 99.97%
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eMolecules 99584-10-8 | 6-Amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one | ChemScene | MFCD07801206 | 164.164 | C8H8N2O2 | 95.000 | Cn1c2ccc(N)cc2oc1=O | 100mg | 680025319
6-Amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one | ChemScene | 99584-10-8 | MFCD07801206 | 164.164 | C8H8N2O2 | 95.000 | Cn1c2ccc(N)cc2oc1=O | 100mg | 680025319
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eMolecules 74124-79-1 | N,N'-DISUCCINIMIDYL CARBONATE | AstaTech | MFCD00009767 | 256.170 | C9H8N2O7 | 95.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100g | 490832455
N,N'-DISUCCINIMIDYL CARBONATE | AstaTech | 74124-79-1 | MFCD00009767 | 256.170 | C9H8N2O7 | 95.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100g | 490832455
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TARGETMOL CHEMICALS INC Methylthiouracil 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism. Purity 100%
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Medchemexpress LLC Bay 59-3074 100Mg | HY-100488-100MG
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Bay 59-3074 100Mg
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eMolecules 77717-71-6 | 6-HYDROXYQUINOLINE-5-CARBALDEHYDE | AstaTech | MFCD11869102 | 173.171 | C10H7NO2 | 98.000 | Oc1ccc2ncccc2c1C=O | 0.1g | 633668236
6-HYDROXYQUINOLINE-5-CARBALDEHYDE | AstaTech | 77717-71-6 | MFCD11869102 | 173.171 | C10H7NO2 | 98.000 | Oc1ccc2ncccc2c1C=O | 0.1g | 633668236
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