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Filtered Search Results
eMolecules 20474-15-1 | Ambeed | 99-Diphenyl-910-dihydroacridine | 1g | 525042422 | A135631 | MFCD28127357 | 333.434 | C25H19N
Ambeed | tert-Butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate | 250mg | 525075150 | A160297 | 373604-28-5 | MFCD11977352 | 219.256 | C10H18FNO3
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Medchemexpress LLC 1E7-03 | 1565845-92-2 | 95.1% | 503.55 | C28H29N3O6 | 1MG
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1E7-03 is a low molecular weight tetrahydroquinoline derivative that targets protein phosphatase-1 (PP1) and has been reported to inhibit HIV-1 transcription in peer-reviewed studies. It is supplied as a research reagent with available documentation including a datasheet, certificate of analysis, and safety data sheet, and has specified storage and handling recommendations for long-term stability.
- Low molecular weight tetrahydroquinoline derivative.
- Targets protein phosphatase-1 (PP1).
- Reported to inhibit HIV-1 transcription in published studies.
- Supplied as a small-quantity research reagent (mg scale).
- Purity approximately 95.1% as supplied.
- Documented storage conditions for powder and solution stability.
- Manufacturer provides datasheet, COA, and SDS.
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Chemscene ChemScene | 6-Chloroquinolin-4-ol | 25G | CS-0042920 | 0.98 | 23432-43-1| MFCD00024011 | 179.61
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ChemScene | 6-Chloroquinolin-4-ol | 25G | CS-0042920 | 0.98 | 23432-43-1| MFCD00024011 | 179.61
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5000734381 ACRIDINE-9-CARBOXALD 250MG
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Medchemexpress LLC Cyclopamine | 4449-51-8 | 411.62 | 200 MG
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Cyclopamine is a steroidal alkaloid and a selective Smo inhibitor that acts as a Hedgehog (Hh) pathway antagonist, with an IC50 of 46 nM in Hh cell assays. It is used in research for its ability to suppress cell growth and inhibit Hh signaling.
- Hedgehog (Hh) pathway antagonist
- Selective Smo inhibitor
- Suppresses cell growth
- Inhibits Hh signaling through direct interaction with Smo
- Suitable for research and analytical applications
- Induces tumor remission in medulloblastoma models
- Blocks tumor formation in pancreatic adenocarcinoma cells
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![Medchemexpress LLC 1H-Isoindole-4-carboxamide, 2-[1-(4,4-difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo- | 1262417-51-5 | 99.5% | 395.42 | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385759-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Isoindole-4-carboxamide, 2-[1-(4,4-difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo- | 1262417-51-5 | 99.5% | 395.42 | 200 MG
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NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor for cancer therapy. It is for research use only and not sold to patients.
- Potent PARP-1 inhibitor (Kd=0.009 μM) with 150-fold selectivity over PARP-2 (Kd=1.39 μM).
- Less myelotoxic in vitro compared to olaparib.
- Metabolically stable.
- Modestly inhibits CYP-2B6 (IC50: 8.15 μM) and CYP-2D6 (IC50: 9.51 μM) out of eight isoforms tested.
- Possesses excellent pharmacokinetic profile and nearly complete oral bioavailability in mice and rats.
- Highly efficacious in vivo as a single agent in MDA-MB-436 human breast cancer tumors and in combination with temozolomide in CAPAN-1 human pancreatic tumors.
- Well tolerated at highly efficacious doses and has an excellent ADME profile.
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5000723573 TAMRA AMINE 5-ISOME 25MG
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eMolecules 57334-35-7 | 5-METHOXY-8-QUINOLINOL | MFCD18414704 | 1g
AstaTech | 5-METHOXY-8-QUINOLINOL | 1g | 273172844 | 76306 | 95.000 | 57334-35-7 | MFCD18414704 | 175.187 | C10H9NO2
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![Medchemexpress LLC 9H-Purin-6-amine, 9-(1-methylethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]- | 1353867-91-0 | 99.8% | 335.33 | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387553-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 9H-Purin-6-amine, 9-(1-methylethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]- | 1353867-91-0 | 99.8% | 335.33 | 200 MG
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Longdaysin is an inhibitor of the Wnt/β-catenin signaling pathway, exerting antitumor effects by blocking CK1δ/ε-dependent Wnt signaling. It inhibits CK1α, CK1δ, CDK7, and ERK2 with IC50s of 5.6 μM, 8.8 μM, 29 μM, and 52 μM, respectively.
- Inhibitor of the Wnt/β-catenin signaling pathway.
- Exerts antitumor effects by blocking CK1δ/ε-dependent Wnt signaling.
- Inhibits CK1α, CK1δ, CDK7, and ERK2.
- Lengthens circadian period in adult tail fibroblasts, lung explants, and SCN explants.
- Inhibits colony formation, migration, invasion, and sphere formation of breast cancer cells.
- Increases circadian period in zebrafish.
- Inhibits tumor growth in xenograft mice.
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eMolecules 1952360-91-6 | (Fmoc-amino)-PEG12-C2-carboxylic acid | Chem-Impex | MFCD08064302 | 839.973 | C42H65NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 686069702
(Fmoc-amino)-PEG12-C2-carboxylic acid | Chem-Impex | 1952360-91-6 | MFCD08064302 | 839.973 | C42H65NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 686069702
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Medchemexpress LLC Beta-ionone | 14901-07-6 | MFCD00001549 | 99.9% | 192.30 g·mol⁻¹ | C13H20O | 200 MG
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β-Ionone is a small aromatic ketone (C13H20O) used as a research reagent and analytical standard. It is a light yellow to colorless liquid and has reported activity inducing apoptosis in gastric adenocarcinoma SGC7901 cells.
- CAS number: 14901-07-6
- Molecular formula: C13H20O
- Molecular weight: 192.30 g·mol⁻¹
- Purity: ~99.9% (high purity for research)
- Available pack sizes: 10 mM (1 mL in DMSO), 100 mg, 200 mg, 500 mg, 1 g
- Typical applications: apoptosis research and analytical assays
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Medchemexpress LLC 1,4,7-Triazonane | 4730-54-5 | 129.20 | 1 ML
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1,4,7-Triazonane (1,4,7-Triazacyclononane) is an intermediate used in the synthesis of 1,4,7-trifunctionalized derivatives. It serves as a possible reagent for compleximetric titrations due to its high cation-binding selectivity and has applications in metal complexation. The compound exhibits an IC50 of 980 μM against human L3.6pl cells, indicating its cytotoxic potential.
- Intermediate in the synthesis of 1,4,7-trifunctionalized derivatives
- Possible reagent for compleximetric titrations
- Exhibits high cation-binding selectivity
- Applications in metal complexation
- Cytotoxic against human L3.6pl cells (IC50 = 980 μM)
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eMolecules 31127-85-2 | 4,7,10,13-tetraoxahexadecanedioic acid | Absolute Chiral | MFCD22201545 | 294.300 | C12H22O8 | 0.000 | OC(=O)CCOCCOCCOCCOCCC(O)=O | 2.5g | 788438027
4,7,10,13-tetraoxahexadecanedioic acid | Absolute Chiral | 31127-85-2 | MFCD22201545 | 294.300 | C12H22O8 | 0.000 | OC(=O)CCOCCOCCOCCOCCC(O)=O | 2.5g | 788438027
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eMolecules 58794-09-5 | 7-bromoisoquinoline | Pharmablock | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 2.5g | 686928965
7-bromoisoquinoline | Pharmablock | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2ccncc2c1 | 2.5g | 686928965
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Medchemexpress LLC ANIMAL-FREE IL-31 H 10UG
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5000178002 ANIMAL-FREE IL-31 H 10UG
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