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Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1 – 13 of 13 results
1

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 50 MG
SDP

MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor with high binding affinity against MDM2 (Kd=8.2 nM) and has antitumor activity.

  • Potent MDM2-p53 protein-protein interaction (PPI) inhibitor
  • High binding affinity against MDM2 (Kd=8.2 nM)
  • Antitumor activity
  • Available in solid and solution forms
  • Soluble in DMSO (≥ 53 mg/mL)

ENCOMPASS_PREFERRED
2

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 100 MG
SDP

MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor. It demonstrates high binding affinity against MDM2 and exhibits antitumor activity. An analog, MI-77301, shows even higher binding affinity and more pronounced antitumor activity in various p53 xenograft models.

  • Potent MDM2-p53 protein-protein interaction (PPI) inhibitor.
  • High binding affinity against MDM2 (Kd=8.2 nM).
  • Exhibits antitumor activity.
  • Analog shows enhanced binding affinity and antitumor activity.
  • Effective in various p53 xenograft models including osteosarcoma, human prostate, melanoma, colorectal tumor, and human acute lymphoblastic leukemia.

ENCOMPASS_PREFERRED
3

Medchemexpress LLC Rebastinib (DCC-2036) | 1020172-07-9 | 99.84% | 200 MG
SDP

Rebastinib is an orally active, non-ATP-competitive inhibitor that targets Bcr-Abl, including its wild-type and T315I mutant forms. It also demonstrates inhibitory activity against SRC, KDR, FLT3, and Tie-2, while showing minimal activity against c-Kit.

  • Orally active.
  • Non-ATP-competitive inhibition of Bcr-Abl.
  • Effective against wild-type and T315I mutant Bcr-Abl.
  • Inhibits other kinases such as SRC, KDR, FLT3, and Tie-2.
  • Demonstrates low activity toward c-Kit.
  • Potently inhibits both inactive and active forms of ABL1.
  • Effective against several common TKI-resistant Bcr-Abl mutants.
  • Inhibits proliferation of cells expressing Bcr-Abl and Ph+ cell lines.
  • Reduces autophosphorylation of Bcr-Abl and phosphorylation of STAT5.

ENCOMPASS_PREFERRED
4

Medchemexpress LLC MI-773 | 1303607-07-9 | MFCD28168022 | 96.3% | 562.50 | C29H34Cl2FN3O3 | 10 MG
SDP

MI-773 is a small-molecule inhibitor of the MDM2-p53 protein-protein interaction with high binding affinity for MDM2 and reported antitumor activity in preclinical studies. It is provided as a research-grade compound for use in cancer biology and p53 pathway experiments.

  • High-affinity MDM2 binding (reported Kd 8.2 nM).
  • Reported antitumor activity in preclinical studies.
  • Provided as a research-grade compound suitable for in vitro and in vivo studies.
  • Available in small mg-scale quantities for research use.
  • Molecular weight 562.50 and formula C29H34Cl2FN3O3 for reference.

ENCOMPASS_PREFERRED
5

Medchemexpress LLC 1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-4-carboxylic acid | 368866-07-3 | MFCD02683117 | 99.4% | 466.53 | C26H30N2O6 | 1 ML
SDP

SARS-CoV-2-IN-86 is a research-grade small molecule inhibitor of SARS-CoV-2 methyltransferases (nsp14 and nsp16), provided for in vitro biochemical and antiviral studies. It is available as solid material and as a 10 mM solution in DMSO, with documented purity and storage recommendations to support reproducible experimental use.

  • High purity (99.35%) for reproducible results.
  • Available as 10 mM solution in DMSO or as solid for flexible assay workflows.
  • Well-characterized chemical identity (CAS 368866-07-3) and formula for traceability.
  • Suitable for biochemical methyltransferase and antiviral research applications.
  • Defined storage conditions to preserve stability in powder and solution formats.
  • Datasheet available with specification and handling information.

ENCOMPASS_PREFERRED
6

Sigma Aldrich Xanthene-9-carboxylic acid

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

ENCOMPASS
CAS 82-07-5
7

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

ENCOMPASS_PREFERRED
8

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

ENCOMPASS_PREFERRED
9

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

ENCOMPASS_PREFERRED
10

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

ENCOMPASS_PREFERRED
11

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

ENCOMPASS_PREFERRED
12

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

ENCOMPASS_PREFERRED
13

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

ENCOMPASS_PREFERRED