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Tetrahydroisoquinolines

Organic heterocyclic compounds that consist of an isoquinoline ring with no double bonds; contains a benzene ring fused to a six-membered ring with one nitrogen atom and five carbon atoms.
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Keyword Search:
46 – 60 of 295 results
46

Medchemexpress LLC Nampt-IN-3 | 2121591-52-2 | 99.0% | 503.55 | 100 MG
SDP

Nampt-IN-3 (Compound 35) simultaneously inhibits nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. It effectively induces cell apoptosis and autophagy, leading to cell death.

  • Inhibits nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM.
  • Effectively induces cell apoptosis and autophagy.
  • Leads to cell death.
  • Demonstrates cytotoxicity in human HCT116 cells with an IC50 of 2.4 μM.
  • Demonstrates cytotoxicity in human HepG2 cells with an IC50 of 4.5 μM.
  • Demonstrates cytotoxicity in human MDA-MB-231 cells with an IC50 of 10 μM.

ENCOMPASS_PREFERRED
47

Medchemexpress LLC HY-15954A 2mg Medchemexpress, NVP-CGM097 (stereoisomer) CAS: Purity:>98%
SDP

Medchemexpress, HY-15954A 2mg NVP-CGM097 (stereoisomer) CAS: NVP-CGM097 (stereoisomer) is a stereoisomer of NVP-CGM097, with no special bioactivity. NVP-CGM097 is a potent and selective MDM2 inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

ENCOMPASS_PREFERRED
48

eMolecules​ 1313367-56-4 | Medchem Express | NVP-CGM097 (sulfate) | 2mg | 446267024 | HY-15954B | MFCD31382179 | 757.34 | C38H49ClN4O8S

ChemScene | Ethyl 4-oxo-4H-pyran-2-carboxylate | 100mg | 632303729 | CS-0160785 | 1551-45-7 | MFCD17012130 | 168.148 | C8H8O4

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

ENCOMPASS_PREFERRED
Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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49

Medchemexpress LLC NBI-31772 | 374620-70-9 | 98.88% | 341.27 | 10 MG
SDP

NBI-31772 is a non-selective IGFBP inhibitor with a Ki of 47 nM. It demonstrates neuroprotective effects, reduces infarct volume during cerebral ischemia, and can restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. It is suitable for various research applications.

  • Inhibits IGFBP with a Ki of 47 nM
  • Demonstrates neuroprotective effects
  • Reduces infarct volume during cerebral ischemia
  • Restores or enhances proteoglycan synthesis in osteoarticular chondrocytes
  • Increases the effect of IGF3 on zebrafish oocyte maturation
  • For research use only

ENCOMPASS_PREFERRED
50

eMolecules​ 1430844-80-6 | Medchem Express | A-1331852 | 5mg | 446270225 | HY-19741 | 658.82 | C38H38N6O3S

Ambeed | Methyl 2-(methylthio)-4-(trifluoromethyl)benzoate | 250mg | 598443895 | A489460 | 192805-69-9 | MFCD14635484 | 250.240 | C10H9F3O2S

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>

ENCOMPASS_PREFERRED
Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
51

eMolecules​ 849675-66-7 | Medchem Express | Encequidar | 5mg | 446263261 | HY-13646 | MFCD25976625 | 688.741 | C38H36N6O7

Medchem Express | Encequidar | 5mg | 446263261 | HY-13646 | 849675-66-7 | MFCD25976625 | 688.741 | C38H36N6O7

ENCOMPASS_PREFERRED
52

eMolecules​ 843653-03-2 | (6-Fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)-methanol | J & W PharmLab LLC | MFCD11110465 | 219.259 | C13H14FNO | 96.000 | OCC1CCc2[nH]c3ccc(F)cc3c2C1 | 1g | 437234094

(6-Fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)-methanol | J & W PharmLab LLC | 843653-03-2 | MFCD11110465 | 219.259 | C13H14FNO | 96.000 | OCC1CCc2[nH]c3ccc(F)cc3c2C1 | 1g | 437234094

ENCOMPASS_PREFERRED
53

Medchemexpress LLC Ecteinascidin 770 | 114899-80-8 | 99.8% | 770.85 g/mol | C40H42N4O10S | 10 MG
SDP

Ecteinascidin 770 is a 1,2,3,4-tetrahydroisoquinoline alkaloid natural product used in preclinical cancer research for its potent cytotoxic and apoptosis-inducing activities. It is typically handled as a solid and prepared in solvent for in vitro assays, showing low-nanomolar inhibitory potency across several human tumor cell lines.

  • Induces apoptosis in tumor cell lines.
  • Exhibits low-nanomolar potency (reported IC50 values in multiple lines).
  • Molecular formula C40H42N4O10S and molecular weight ~770.85 g/mol.
  • Soluble in DMSO for biological testing.
  • Supplied as a small solid vial suitable for research use.

ENCOMPASS_PREFERRED
54

eMolecules​ 176641-34-2 | 6-Methoxy-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid methyl ester hydrochloride | Combi-Blocks | MFCD09878831 | 257.710 | C12H16ClNO3 | 95.000 | Cl.COC(=O)C1CCc2cc(OC)ccc2N1 | 1g | 415502234

6-Methoxy-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid methyl ester hydrochloride | Combi-Blocks | 176641-34-2 | MFCD09878831 | 257.710 | C12H16ClNO3 | 95.000 | Cl.COC(=O)C1CCc2cc(OC)ccc2N1 | 1g | 415502234

ENCOMPASS_PREFERRED
55

eMolecules​ 24693-40-1 | 8-Methoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride | J & W PharmLab LLC | MFCD05861545 | 199.680 | C10H14ClNO | 95.000 | Cl.COc1cccc2CCNCc12 | 5g | 289352726

8-Methoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride | J & W PharmLab LLC | 24693-40-1 | MFCD05861545 | 199.680 | C10H14ClNO | 95.000 | Cl.COc1cccc2CCNCc12 | 5g | 289352726

ENCOMPASS_PREFERRED
56

eMolecules​ 871224-64-5 | Medchem Express | Almorexant | 5mg | 446259249 | HY-10805 | MFCD22419385 | 512.573 | C29H31F3N2O3

Medchem Express | Almorexant | 5mg | 446259249 | HY-10805 | 871224-64-5 | MFCD22419385 | 512.573 | C29H31F3N2O3

ENCOMPASS_PREFERRED
57

eMolecules​ Berbamine dihydrochloride | 6078-17-7 | MFCD11982910 | 1g

Matrix Scientific | Berbamine dihydrochloride | 1g | 490660386 | 99125 | 95.000 | 6078-17-7 | MFCD11982910 | 681.650 | C37H42Cl2N2O6

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool

ENCOMPASS_PREFERRED
58

Selleck Chemical LLC PF-00562271 Besylate-5mg
SDP

PF-00562271 Besylate (PF-562271) is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.

ENCOMPASS_PREFERRED
59

Medchemexpress LLC Encequidar mesylate | 849675-87-2 | MFCD25976626 | 99.8% | 784.8 g/mol | C39H40N6O10S | 5 MG
SDP

Encequidar mesylate is the mesylate salt of encequidar, a potent, competitive inhibitor of P-glycoprotein (P-gp/ABCB1) used as a research tool to probe transporter-mediated drug disposition, oral bioavailability, and drug-drug interactions. It is provided as a high-purity solid suitable for in vitro and in vivo studies.

  • Potent competitive inhibitor of P-glycoprotein for transporter studies.
  • High reported purity (99.82%), suitable for analytical and biological work.
  • Available in small pre-weighed quantities for dosing and assay use.
  • Provides molecular formula and molecular weight for formulation and calculation.
  • Supplied as a mesylate salt to improve stability and handling.

ENCOMPASS_PREFERRED
60

eMolecules​ 1340888-73-4 | 2-Phenyl-6,7,8,8a-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(5H)-one | Apollo Scientific266.304 | C15H14N4O | 95.000 | O=C1C2CNCCC2=Nc2cc(nn12)-c1ccccc1 | 1g | 562461331

2-Phenyl-6,7,8,8a-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(5H)-one | Apollo Scientific | 1340888-73-4266.304 | C15H14N4O | 95.000 | O=C1C2CNCCC2=Nc2cc(nn12)-c1ccccc1 | 1g | 562461331

ENCOMPASS_PREFERRED