Tetrapyrroles and derivatives
Abcam GS 39783, GABAB positive allosteric modulator, 50MG
MW 337.4 Da, Purity >99%. Novel, GABAB positive allosteric modulator (EC50 = 3 μM for [35S]GTPγS binding). Shows anxiolytic and antiaddictive effects *in vivo.* Blood-brain barrier permeable*.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam EMD 386088 hydrochloride, 5-HT6 agonist, 10MG
MW 283.2 Da, Purity >98%. Potent 5-HT6 agonist (IC50 = 7.4 nM in 3H-LSD binding and EC50 = 1.0 nM in a functional cAMP assay). Selective over other 5-HT receptors (IC50 values are 110 (5-HT1D), 180 (5-HT1B), 240 (5-HT2A), 450 (5-HT2C), 620 (5-HT4), 660 (5-HT1A ) and 3000 nM (5-HT7)). Shows moderate affinity at 5-HT3 receptors (IC50 = 34 nM). Impairs memory *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 206553 hydrochloride, 5-HT2B and 5-HT2C receptor antagonist, 10MG
MW 292.33 Da, Purity >99%. Potent and selective 5-HT2B and 5-HT2C serotonin receptor antagonist (pKi values are 7.92 (5-HT2C), 5.78 (5-HT2A), 7.65 (5-HT2B), 1A), 1D), 1E) and 1F). Centrally active following oral administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PNU 282987, alpha7 nAChR agonist, 10MG
MW 301.2 Da, Purity >99%. Selective α7nAChR agonist. Negligible activity at α1β1γδ and α3β4 receptors. High affinity for rat α7nACh receptors (Ki = 26 nM). Functional antagonist at 5-HT₃ receptors (IC₅₀ = 4541 nM).
The product is subject to the following: Abcam Restricted Use Statement
Crescent Chemical Co Inc VITAMIN B12 CRYST. PURE
Vitamin B12 cryst. pure Non-animal origin. Size - 500MG Storage Conditions - +2 °C TO +8 °C Catalog Number - 38310.02 CAS 68-19-9
Abcam Undecylprodigiosin, Apoptotic and anticancer agent, 1MG
MW 393.6 Da, Purity >93%. Apoptotic and anticancer agent. Selectively induces p53-independant apoptosis in cancer cells. Induces G2/M cell cycle arrest and shows antiproliferative effects. Shows antimalarial and antibactieral effects in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Biliverdin | 114-25-0 | 70.0% | C33H34N4O6 | 10MG
Biliverdin is a green tetrapyrrolic bile pigment produced by heme catabolism, supplied as a research-grade reagent for biochemical and cell biology studies. It is commonly used as an endogenous metabolite in inflammation and heme metabolism research; handle protected from light and prepare DMSO stocks for in vitro work.
Strem, An Ascensus Company CAS# 574-93-6. 5g. Phthalocyanine. MFCD00005085
CAS# 574-93-6. 5g. Phthalocyanine. MFCD00005085. Molecular Weight: 514.55. Molecular Formula: C32H18N8. Color/form: blue black pwdr. Strem# 07-1700. http://www.strem.com/catalog/v/07-1700/
Abcam Bisindolylmaleimide II, PKC inhibitor, 1MG
MW 438.5 Da, Purity >97%. Potent, selective ATP-competitive PKC inhibitor (IC₅₀ values are 0.01, 0.75 and 2 μM for PKC, phosphorylase kinase and PKA respectively). Potent noncompetitive nAChR antagonist (IC₅₀ = 0.03 μM, catecholamine secretion in nicotine-stimulated PC-12 cells). Shows more potent antinicotinic effects than Bisindolylmaleimide IV (ab144208) and V (ab144205). Induces apoptosis and shows antiproliferative effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Undecylprodigiosin, Apoptotic and anticancer agent, 250UG
MW 393.6 Da, Purity >93%. Apoptotic and anticancer agent. Selectively induces p53-independant apoptosis in cancer cells. Induces G2/M cell cycle arrest and shows antiproliferative effects. Shows antimalarial and antibactieral effects in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Bilirubin conjugate disodium | 68683-34-1 | MFCD00044931 | 95.0% | C37H44N6Na2O10S2 | 10MG
Bilirubin conjugate disodium is a water-soluble, ditaurate derivative of bilirubin used as a research reagent and drug-metabolite reference for studies of heme metabolism and assay development. The material is supplied as the disodium salt (C37H44N6Na2O10S2) and is accompanied by analytical documentation for laboratory use.
- High purity (95.0%).
- Water-soluble disodium salt for aqueous assays.
- Suitable as a reference standard in bilirubin and drug-metabolite studies.
- Provided with certificate of analysis and safety data sheet.
- Available in small quantity packages for research applications.
Creative Biomart Hemin
The product is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.
Abcam Radicicol, Heat shock protein (HSP) 90 inhibitor, 1MG
MW 364.8 Da, Purity >99%. Heat shock protein 90 inhibitor and antifungal antibiotic. Binds to the N-terminal ATP/ADP-binding domain suppressing cell transformation induced by src, ras and mos. Induces cell cycle arrest at G₁-S phase. Shows antiangiogenic effects in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC HY-B0754 100mg Medchemexpress, Hematoporphyrin CAS:14459-29-1 Purity:>98%
Medchemexpress, HY-B0754 100mg Hematoporphyrin CAS:14459-29-1 Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.