Tetrapyrroles and derivatives
Enzo Life Sciences Protoporphyrin IX (free acid) (1g). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Appearance: Purple to dark brown solid. Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
Medchemexpress LLC Zinc(II)-protoporphyrin IX | 15442-64-5 | 98.9% | 626.02 | C34H32N4O4Zn | 5 MG
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is a porphyrin-based small molecule used in biomedical research as a competitive heme oxygenase-1 (HO-1) inhibitor and as a biochemical marker of iron deficiency. It is supplied as a solid for laboratory studies and should be stored sealed and protected from moisture at low temperatures for stability.
- Competitive heme oxygenase-1 (HO-1) inhibitor
- Used as a screening marker of iron deficiency in biological samples
- High purity suitable for research assays (98.9%)
- Available in milligram-scale packages for laboratory use
- Requires sealed, moisture-free storage at low temperature
TARGETMOL CHEMICALS INC Tin-protoporphyrin IX dichlori
Also available in 1 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses. Purity 98%
Medchemexpress LLC HIF-1 alpha (556-574) | 1201633-99-9 | 99.4% | 2256.54 | 5 MG
HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Tin protoporphyrin IX dichloride | 14325-05-4 | 96.2% | 750.26 g/mol | C34H32Cl2N4O4Sn | 100 MG
Tin protoporphyrin IX dichloride is a metalloporphyrin research reagent that acts as a potent inhibitor of heme oxygenase enzymes. It is provided as a milligram-scale crystalline solid intended for biochemical and cell-based studies to probe heme metabolism, oxidative stress, and related pathways.
- Potent inhibitor of heme oxygenase enzymes.
- Suitable for in vitro and in vivo research applications.
- Available in milligram-scale sizes, including 100 MG.
- High reported purity for research use (approximately 96.2%).
- Supplied as a stable solid for routine laboratory handling.
Apexbio Technology LLC Hematoporphyrin dihydrochloride 17696-69-4 100mg
Hematoporphyrin dihydrochloride (CAS 17696-69-4) is a porphyrin-based photosensitizer utilized in biomedical research Upon exposure to specific wavelengths of light it generates reactive oxygen species that induce apoptosis in cancer cells as demonstrated in U87 glioma cell models In vivo studies indicate that hematoporphyrin dihydrochloride suppresses tumor progression This compound also serves as a substrate in heme-binding protein affinity chromatography supporting protein interaction studies Its primary research applications include the investigation of tumor cell apoptosis mechanisms and the evaluation of photodynamic therapy strategies
![eMolecules 19301-09-8 | 1H-BENZO[D]AZEPIN-2(3H)-ONE | AstaTech | MFCD01101239 | 159.188 | C10H9NO | 97.000 | O=C1Cc2ccccc2C=CN1 | 0.25g | 256638974](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502466756.JPG-250.jpg)
eMolecules 19301-09-8 | 1H-BENZO[D]AZEPIN-2(3H)-ONE | AstaTech | MFCD01101239 | 159.188 | C10H9NO | 97.000 | O=C1Cc2ccccc2C=CN1 | 0.25g | 256638974
1H-BENZO[D]AZEPIN-2(3H)-ONE | AstaTech | 19301-09-8 | MFCD01101239 | 159.188 | C10H9NO | 97.000 | O=C1Cc2ccccc2C=CN1 | 0.25g | 256638974
Medchemexpress LLC 2-Amino-3-(2-chlorophenyl)propanoic acid | 14091-11-3 | 199.63 | 25 G
2-Amino-3-(2-chlorophenyl)propanoic acid is a phenylalanine derivative intended for research use. Amino acids and their derivatives are recognized as beneficial ergogenic dietary substances, commercially used as supplements. They influence anabolic hormone secretion, fuel supply during exercise, mental performance under stress, and help prevent exercise-induced muscle damage.
- Phenylalanine derivative
- Intended for research use
- Functions as an ergogenic supplement
- Influences anabolic hormone secretion
- Modulates fuel supply during exercise
- Enhances mental performance during stress
- Aids in preventing exercise-induced muscle damage
Medchemexpress LLC Pyraclonil | 158353-15-2 | 97.0% | 314.77 | 50 MG
Pyraclonil is a chemical compound that acts as a protoporphyrinogen oxidase (PPO) inhibitor. It functions as a herbicide and demonstrates high effectiveness in controlling both susceptible and multiple-herbicide-resistant populations of *E. indica*. Additionally, Pyraclonil is noted for its role as a click chemistry reagent, containing an Alkyne group which allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Azide groups.
- Mechanism of action: PPO inhibitor.
- Application: herbicide, effective against susceptible and multiple-herbicide-resistant *E. indica*.
- Chemical reactivity: click chemistry reagent with an alkyne group, capable of CuAAc reactions with azide-containing molecules.
- In vitro efficacy: shows good control in vitro, leading to 94.5-94.9% and 89.5-90.4% fresh-weight reductions in susceptible and resistant populations, respectively.
Medchemexpress LLC Biliverdin | 114-25-0 | MFCD00870216 | 70.0% | 582.65 | C33H34N4O6 | 5 MG
Biliverdin is a tetrapyrrolic bile pigment produced during heme catabolism and provided as a research reagent for biochemical and cellular studies. It is investigated for antioxidant, anti-inflammatory, and immunomodulatory effects and for its role in heme metabolism and tissue protection. For research use only.
- Endogenous metabolite used in biochemical and cell biology research.
- Exhibits antioxidant, anti-inflammatory, and immunosuppressant properties.
- Soluble in DMSO at about 3 mg/mL; ultrasonic warming recommended.
- Store at -20°C protected from light; in solvent store at -80°C for long-term stability.
- Available in small milligram quantities suitable for laboratory experiments.