Thiolactams
4-Thiouridine, ∽98, MP Biomedicals™
CAS: 13957-31-8 Molecular Formula: C9H12N2O5S Molecular Weight (g/mol): 260.26 MDL Number: MFCD00006538 InChI Key: ZLOIGESWDJYCTF-XVFCMESISA-N Synonym: 4-thiouridine,thiouridine,uridine, 4-thio,1-beta-d-ribofuranosyl-4-thiouracil,1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,s4u,thiouridine van,uridine,4-thio,4-thio-d-uridine PubChem CID: 3032615 ChEBI: CHEBI:20480 IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O
4-Thiouridine, 98+%
CAS: 13957-31-8 Molecular Formula: C9H12N2O5S Molecular Weight (g/mol): 260.26 MDL Number: MFCD00006538 InChI Key: ZLOIGESWDJYCTF-XVFCMESISA-N PubChem CID: 3032615 ChEBI: CHEBI:20480 SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O
4-Thiouridine, MP Biomedicals™
CAS: 13957-31-8 Molecular Formula: C9H12N2O5S Molecular Weight (g/mol): 260.26 MDL Number: MFCD00006538 InChI Key: ZLOIGESWDJYCTF-XVFCMESISA-N Synonym: 4-thiouridine,thiouridine,uridine, 4-thio,1-beta-d-ribofuranosyl-4-thiouracil,1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one,s4u,thiouridine van,uridine,4-thio,4-thio-d-uridine PubChem CID: 3032615 ChEBI: CHEBI:20480 IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=S)NC1=O
4-Thiouracil, 97%, Thermo Scientific Chemicals
CAS: 591-28-6 Molecular Formula: C4H4N2OS Molecular Weight (g/mol): 128.15 MDL Number: MFCD00090842 InChI Key: OVONXEQGWXGFJD-UHFFFAOYSA-N Synonym: 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci PubChem CID: 2734394 IUPAC Name: 4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: O=C1NC=CC(=S)N1
Thermo Scientific Chemicals 4-Thiouracil, 97%
CAS: 591-28-6 Molecular Formula: C4H4N2OS Molecular Weight (g/mol): 128.15 MDL Number: MFCD00090842 InChI Key: OVONXEQGWXGFJD-UHFFFAOYSA-N Synonym: 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci PubChem CID: 2734394 IUPAC Name: 4-sulfanylidene-1H-pyrimidin-2-one SMILES: O=C1NC=CC(=S)N1
4-Thiouracil 97.0+%, TCI America™
CAS: 591-28-6 Molecular Formula: C4H4N2OS Molecular Weight (g/mol): 128.15 MDL Number: MFCD00090842 InChI Key: OVONXEQGWXGFJD-UHFFFAOYSA-N Synonym: 4-thiouracil,2-hydroxy-4 1h-pyrimidinethione,4-thioxo-3,4-dihydropyrimidin-2 1h-one,2-hydroxy-4-mercaptopyrimidine,uracil, 4-thio,4-mercaptopyrimidin-2-ol,4-sulfanylpyrimidin-2-ol,2-hydroxy-4-thiopyrimidine,2 1h-pyrimidinone, 3,4-dihydro-4-thioxo,2 1h-pyrimidinone, 4-mercapto-9ci PubChem CID: 2734394 IUPAC Name: 4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one SMILES: O=C1NC=CC(=S)N1
Sigma Aldrich 3-(Pyrrolidin-1-ylmethyl)aniline dihydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC 4-Thiouridine 5'-triphosphate tetralithium | 20188-72-1 | C9H11Li4N2O14P3S | 25 MG
4-Thiouridine 5'-triphosphate tetralithium (4-Thio-UTP tetralithium) is a UTP analog and a potent P2Y2 and P2Y4 agonist, with EC50 values of 35 nM for hP2Y2 and 350 nM for hP2Y4. This laboratory chemical is suitable for cross-linking experiments and transcriptional complex labeling studies. It is for research use only and has not been fully validated for medical applications.
- Potent P2Y2 and P2Y4 agonist
- EC50 values of 35 nM for hP2Y2 and 350 nM for hP2Y4
- Suitable for cross-linking experiments
- Useful in transcriptional complex labeling studies
Medchemexpress LLC 4-Thiouracil | 591-28-6 | 99.98% | 128.15 | 100 MG
4-Thiouracil is a thionucleobase possessing cytostatic properties. It functions as a biological photoprobe for detecting RNA structures and nucleic acid-nucleic acid contacts. Additionally, it serves as a potent ultraviolet A (UVA) photosensitizer, generating reactive oxygen species (O2). 4-Thiouracil holds promise for research in photocrosslinking, photodamage, and photodynamic therapy.
- Thionucleobase with cytostatic properties.
- Can be used as biological photoprobes to detect RNA structures and nucleic acid-nucleic acid contacts.
- Acts as a strong UVA photosensitizer, providing a source of reactive oxygen species (O2).
- Promising for research in photocrosslinking, photodamage, and photodynamic therapy.
Medchemexpress LLC 4-thiouridine 5′-triphosphate tetralithium | 20188-72-1 | C9H11Li4N2O14P3S | 5 MG
4-Thiouridine 5′-triphosphate tetralithium (4-Thio-UTP) is a UTP analog and a potent P2Y2 and P2Y4 receptor agonist, with EC50 values of 35 nM for hP2Y2 and 350 nM for hP2Y4. This compound is a light yellow to yellow solid suitable for various research applications.
- UTP analog
- Potent P2Y2 and P2Y4 receptor agonist
- Suitable for cross-linking experiments
- Suitable for transcriptional complex labeling studies
- Ships at room temperature in the continental US
- Store at 4°C, sealed, away from moisture and light
- For research use only
Medchemexpress LLC 4-Thiouridine | 13957-31-8 | 100.0% | 260.27 | 5 MG
4-Thiouridine is a ribonucleoside analog widely used in RNA analysis and (m)RNA labeling. It inhibits rRNA synthesis and causes a nucleolar stress response.
- Ribonucleoside analog
- Used in RNA analysis and (m)RNA labeling
- Inhibits rRNA synthesis
- Causes a nucleolar stress response
- At 0-10 μM, it labels and purifies nascent rRNA without significantly affecting rRNA synthesis
- At ≥50 μM, it strongly inhibits production and processing of rRNA
Cayman Chemical 4-ThIouracIl 1g
A site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts
Medchemexpress LLC Uridine,4-thio- | 13957-31-8 | 99.98% | 260.27 | 1 ML
4-Thiouridine is a ribonucleoside analog widely used in RNA analysis and (m)RNA labeling. It works by inhibiting rRNA synthesis, which leads to a nucleolar stress response. It is intended for research use only and is not sold to patients.
- Ribonucleoside analog
- Used in RNA analysis and mRNA labeling
- Inhibits rRNA synthesis
- Causes a nucleolar stress response
- High purity: 99.98%
- Labels and purifies nascent rRNA at 0-10 μM
- Strongly inhibits rRNA production and processing at ≥50 μM
Apexbio Technology LLC 2-Thiouracil 141-90-2 1g
2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
Apexbio Technology LLC 2-Thiouracil 141-90-2 10mM (in 1mL DMSO)
2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings