Alkanolamines
Thermo Scientific Chemicals Tris(hydroxymethyl)aminomethane, 99.8%, for analysis, biochemical grade
CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.14 MDL Number: MFCD00004679 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: trometamol,tris,tromethamine,tris hydroxymethyl aminomethane,tham,trisamine,tris buffer,trizma,2-amino-2-hydroxymethyl propane-1,3-diol,tris base PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O
Thermo Scientific Chemicals Tris(hydroxymethyl)aminomethane, 99+%, for biochemistry
CAS: 77-86-1 MDL Number: MFCD00004679 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: trometamol,tris,tromethamine,tris hydroxymethyl aminomethane,tham,trisamine,tris buffer,trizma,2-amino-2-hydroxymethyl propane-1,3-diol,tris base PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O
Saponin, From Saponegin Glycosides (Off-White Powder/Practical Grade), MP Biomedicals
CAS: 637-39-8 Molecular Formula: C6H16ClNO3 Molecular Weight (g/mol): 185.648 InChI Key: HHLJUSLZGFYWKW-UHFFFAOYSA-N Synonym: triethanolamine hydrochloride,tea-hydrochloride,triethanolammonium chloride,2,2',2-nitrilotriethanol hydrochloride,ethanol, 2,2',2-nitrilotris-, hydrochloride,2,2',2-nitrilotrisethanol hydrochloride,unii-r297uj9qdy,tris 2-hydroxyethyl ammonium chloride,tris 2-hydroxyethyl amine hydrochloride,r297uj9qdy PubChem CID: 101814 IUPAC Name: 2-[bis(2-hydroxyethyl)amino]ethanol;hydrochloride SMILES: C(CO)N(CCO)CCO.Cl
Sigma Aldrich Fine Chemicals Biosciences Trizma base BioPerformance Certified, meets EP, USP testing specifications, cell culture tested, 99.9 (titration), 77-86-1, MFCD00004679
Trizma base BioPerformance Certified, meets EP, USP testing specifications, cell culture tested, 99.9 (titration)
Medchemexpress LLC 6-(Dimethylamino)purine | 938-55-6 | 99.90% | 163.18 | 100 MG
6-(Dimethylamino)purine is a serine threonine protein kinase inhibitor. It can inhibit prolactin-induced expression of lactoprotein genes in rabbit mammary gland cells and affect the maturation of mammalian oocytes. It leads to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induces apoptosis in lymphoma cells.
- Inhibits protein kinases
- Blocks DNA synthesis in activated mammalian oocytes
- Affects sperm motility and vitality
- Induces apoptosis in lymphoma cells
- Accelerates transition to interphase in activated mouse oocytes
Medchemexpress LLC 6-(Dimethylamino)purine | 938-55-6 | 99.9% | 163.18 | 1 ML
6-(Dimethylamino)purine is a serine threonine protein kinase inhibitor that can affect various cellular processes. It is used in research to study cellular mechanisms.
- Inhibits prolactin-induced expression of lactoprotein genes in rabbit mammary gland cells.
- Affects the maturation of mammalian oocytes.
- Leads to downregulation of genes related to cell proliferation and cell cycle progression.
- Induces apoptosis in lymphoma cells.
Medchemexpress LLC Paris saponin VII | 68124-04-9 | 5 MG
Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin from *Trillium tschonoskii*. It induces apoptosis and robust autophagy in K562/ADR cells, demonstrating potential for leukemia treatment. Its action involves Akt/MAPK and P-gp inhibition, attenuating mitochondrial membrane potential, increasing pro-apoptotic proteins like Bax and cytochrome c, and decreasing anti-apoptotic proteins such as Bcl-2, caspases, PARP-1, and p-Akt.
- Isolated from *Trillium tschonoskii*.
- Induces apoptosis and autophagy in K562/ADR cells.
- Inhibits Akt/MAPK and P-gp.
- Attenuates mitochondrial membrane potential.
- Modulates apoptosis-related proteins (e.g., Bax, Bcl-2, caspases).
- Potential for leukemia treatment.
- Inhibits adriamycin-resistant leukemia cell growth.
- Suppresses cell proliferation via G0/G1 arrest.
- Enhances adriamycin's anticancer efficacy in xenograft models.
Medchemexpress LLC Stearyldiethanolamine | 10213-78-2 | 100 MG
Stearyldiethanolamine is an amine-based surfactant used in the development of antibacterial freshness-keeping film or antibacterial nonwoven fabric. It can also serve as a collector for quartz and malachite surfaces, efficiently recovering malachite. This compound disrupts bacterial cell membranes with its alkyl chain, leading to irreversible damage and cell death.
- Used in antibacterial freshness-keeping film.
- Used in antibacterial nonwoven fabric.
- Functions as a collector for quartz and malachite.
- Efficiently recovers malachite from quartz.
- Disrupts bacterial cell membranes.
- Increases recovery of malachite and quartz dose-dependently.
- Exhibits inhibitory effects against Gram-positive and Gram-negative bacteria.
Medchemexpress LLC Beta-N-methylamino-L-alanine hydrochloride | 16012-55-8 | 98.0% | 154.60 | 25 MG
Beta-N-methylamino-L-alanine hydrochloride is a neurotoxin produced by cyanobacteria. It activates mGluR3 and inhibits PKC, and can be used in the research of neurodegenerative diseases and immune diseases.
- Activates mGluR3
- Inhibits PKC
- Useful for research into neurodegenerative diseases
- Useful for research into immune diseases
- Inhibits melatonin synthesis
- Shows toxicity in PC12 cells
- Suppresses cell cycle progression at the G1/S checkpoint
- Perturbs alanine, aspartate, and glutamate metabolism pathways
- Induces developmental neurotoxicity
- Causes neurological and pathological phenotypes mimicking amyotrophic lateral sclerosis (ALS)
- Induces in vivo retinal cell death
- Produces oxidative damage in liver and kidney of rats
Sigma Aldrich Fine Chemicals Biosciences 1 Propanol suitable for HP1L
1-Propanol is a linear alcohol. It exhibits Debye-type relaxation process which ressembles the -relaxation and Johari-Goldstein type relaxation features of the supercooled liquids (nonhydrogen-bonding type). It has been tested as a substitute of the fuel for various fuel cells. Its biosynthesis from glucose using Escherichia coli strain has been proposed.
Medchemexpress LLC Miglitol | 72432-03-2 | 98.0% | 500 MG
Miglitol (BAY-m1099) is an orally active antidiabetic compound. It inhibits the breakdown of glycoconjugates into glucose by acting on glycoside hydrolase enzymes known as α-glucosidases. Miglitol also inhibits oxidative stress-induced apoptosis and mitochondrial reactive oxygen species (ROS) over-production in endothelial cells by enhancing AMP-activated protein kinase.
- Orally active antidiabetic compound
- Inhibits breakdown of glycoconjugates into glucose
- Targets glycoside hydrolase enzymes (α-glucosidases)
- Inhibits oxidative stress-induced apoptosis
- Reduces mitochondrial ROS over-production in endothelial cells
- Enhances AMP-activated protein kinase
- Delays onset and development of diabetes
- Helps preserve insulin secretory function of pancreatic islets
Sigma Aldrich Fine Chemicals Biosciences 2 Propanol suitable for HP
2-Propanol (Isopropanol) is a secondary alcohol. It has been tested as substitute to fuel for various fuel cells. Cuo powder dissolved in 2-propanol has been used for the laser ablation assisted synthesis of Cu colloids. Its suspension with Zn(NO3)2 has been employed for the fabrication of titanium dioxide-coated stainless steel (P25-TiO2/SS) photoanode coated with uniformly thick layer of P25-TiO2. This photoanode was used for the electrochemical photocatalytic (ECPC) degradation process.
Sigma Aldrich Fine Chemicals Biosciences 2 Propanol suitable for HP
2-Propanol (Isopropanol) is a secondary alcohol. It has been tested as substitute to fuel for various fuel cells. Cuo powder dissolved in 2-propanol has been used for the laser ablation assisted synthesis of Cu colloids. Its suspension with Zn(NO3)2 has been employed for the fabrication of titanium dioxide-coated stainless steel (P25-TiO2/SS) photoanode coated with uniformly thick layer of P25-TiO2. This photoanode was used for the electrochemical photocatalytic (ECPC) degradation process.
Sigma Aldrich Fine Chemicals Biosciences 2-Propanol suitable for HP
2-Propanol (Isopropanol) is a secondary alcohol. It has been tested as substitute to fuel for various fuel cells. Cuo powder dissolved in 2-propanol has been used for the laser ablation assisted synthesis of Cu colloids. Its suspension with Zn(NO3)2 has been employed for the fabrication of titanium dioxide-coated stainless steel (P25-TiO2/SS) photoanode coated with uniformly thick layer of P25-TiO2. This photoanode was used for the electrochemical photocatalytic (ECPC) degradation process.
Apexbio Technology LLC 3-Azetidinemethanol hydrochloride 928038-44-2 100mg
3-Azetidinemethanol hydrochloride (CAS 928038-44-2) is a nitrogen-containing heterocyclic compound commonly utilized as an intermediate in the synthesis of SHP2 inhibitors SHP2 a protein tyrosine phosphatase plays a regulatory role in cellular signaling pathways that control cell proliferation differentiation and migration Dysregulation of SHP2 function has been implicated in the development of various diseases including cancer By enabling the preparation of SHP2 inhibitors 3-Azetidinemethanol hydrochloride supports research aimed at elucidating the effects of SHP2 inhibition on cellular signaling pathways and exploring novel therapeutic strategies
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