Carboximidamides
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 1 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 30 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 47.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 5 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 250 mL Glass (28-400)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 174.7 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
Medchemexpress LLC GDC-0276 50mg | 1494581-70-2 | 50 MG
Selective, orally active NaV1.7 inhibitor research compound intended for preclinical and clinical pharmacology studies. Demonstrates sub-nanomolar potency and favorable pharmacokinetics; supplied as a high-purity small-molecule solid for laboratory use.
- High purity (99.7%).
- Molecular weight 462.58.
- Chemical formula C24H31FN2O4S.
- Reported potency IC50 = 0.4 nM (NaV1.7).
- Supplied quantity 50 MG.
![Medchemexpress LLC 6-methyl-2-[(3-phenoxypropyl)aminomethyl]quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 g·mol-1 | C20H22N2O2 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239167.png-250.jpg)
Medchemexpress LLC 6-methyl-2-[(3-phenoxypropyl)aminomethyl]quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 g·mol-1 | C20H22N2O2 | 100MG
UCSF924 is a potent and selective dopamine D4 receptor (DRD4) partial agonist used as a chemical probe in neuropsychiatric and pharmacology research. It exhibits an EC50 of 4.2 nM and a Ki of approximately 3 nM for DRD4, with reported lack of off-target activity against more than 320 non-olfactory GPCRs. Supplied as a high-purity research compound for biochemical and cellular studies. Not for human or veterinary use.
- Potent DRD4 partial agonist (EC50 4.2 nM).
- High affinity for DRD4 (Ki ≈ 3 nM).
- Demonstrated selectivity with minimal off-target GPCR activity.
- High purity suitable for biochemical and cellular assays.
- Available in multiple packaging formats and DMSO solutions for assay use.
Medchemexpress LLC (+)-Columbianetin | 3804-70-4 | 246.26 | 5 MG
(+)-Columbianetin is an active compound that functions as an inhibitor of JNK and ERK, and an activator of TGFβ signaling. It effectively mitigates UVA-induced cellular damage by reducing phosphorylation of JNK and ERK, decreasing MMP-1 production, and reversing collagen degradation. Additionally, it provides protection against UVB-induced harm to human keratinocytes.
- Inhibits JNK and ERK pathways.
- Activates TGFβ signaling.
- Reduces MMP-1 production.
- Reverses UVA-induced collagen degradation.
- Alleviates UVA-mediated inhibition of Smad2/3 phosphorylation.
- Regulates AP-1 and ASK1-MAPK signaling pathways.
- Inhibits ROS production.
- Protects human keratinocytes against UVB-induced damage.
- Applicable for research related to skin aging.
TARGETMOL CHEMICALS INC Clonidine hydrochloride 500MG
Also available in 1 mL, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Clonidine hydrochloride (Catapres) is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent. Purity 99.8%
Medchemexpress LLC Fluorizoline | 100MG
Fluorizoline selectively and directly binds to prohibitin 1 (PHB1) and 2 (PHB2) and induces apoptosis Fluorizoline reduces chronic lymphocytic leukemia (CLL) cell viability through the upregulation of NOXA and BIM Fluorizoline exerts antitumor action in a p53-independent manner[1]
Selleck Chemical LLC Clonidine HCl S2458-1g
Clonidine HCl(Kapvay) is a direct-acting 2 adrenergic agonist with an ED50 of 0 02 0 01 mg/kg
Medchemexpress LLC Creatine (Standard) | 57-00-1 | 99.98% | 131.13 | 50 MG
Creatine (Standard) is an analytical standard of Creatine, an endogenous amino acid derivative crucial for cellular energy in muscle and brain. It is designed for research and analytical applications, serving as a reference in various assays.
- Used in qualitative research experiments.
- Used in quantitative research experiments.
- Used in methodological research experiments.
- Applicable in HPLC.
- Applicable in GC.
- Applicable in MS.
Selleck Chemical LLC Clonidine HCl S2458-50mg
Clonidine HCl(Kapvay) is a direct-acting 2 adrenergic agonist with an ED50 of 0 02 0 01 mg/kg
Apexbio Technology LLC Creatine monohydrate 6020-87-7 100mg
Creatine monohydrate (CAS 6020-87-7) is an endogenous amino acid derivative that modulates cellular energy metabolism primarily through its involvement in the phosphocreatine pathway It facilitates the rapid regeneration of adenosine triphosphate (ATP) by serving as a phosphate donor in muscle and neural tissues thereby supporting cellular energy demands during periods of increased metabolic activity Due to its capacity to enhance ATP synthesis and influence muscle contractility creatine monohydrate is widely investigated in studies of muscle disorders and neurodegenerative diseases offering a valuable tool for exploring cellular energy homeostasis in various biomedical research contexts
Apexbio Technology LLC MRTX-1133(Synonyms: MRTX1133, MRTX 1133, Mirati-1133, KRAS G12D inhibitor MRTX1133), 10mg, CAS: 2621928-55-8.
MRTX-1133 (CAS 2621928-55-8) is a non-covalent alkyne-based inhibitor specifically targeting the KRAS G12D mutant protein It binds KRAS G12D with sub-picomolar affinity occupying the Switch II pocket and forming multiple intermolecular interactions Through these interactions MRTX-1133 disrupts SOS1-mediated guanine nucleotide exchange and prevents the assembly of KRAS-GTP/RAF1 signaling complexes thereby inhibiting downstream KRAS-driven signaling pathways MRTX-1133 is applied in cancer biology research to investigate tumor signaling and therapeutic strategies involving KRAS G12D mutations
Sigma Aldrich Fine Chemicals Biosciences Cimetidine hydrochloride United States Pharmacopeia (USP) Reference Standard | 70059-30-2 | MFCD01724314 | 200MG
Cimetidine hydrochloride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 288.8 | 70059-30-2 | MFCD01724314 | 200MG