Carboximidamides
Sigma Aldrich Fine Chemicals Biosciences Cimetidine | 51481-61-9 | MFCD00133296 | 10g
Cimetidine | Mol Wt: 252.34 | 51481-61-9 | MFCD00133296 | 10g
Medchemexpress LLC AN0128, a boron-containing antibacterial and anti-inflammatory agent | 872044-70-7 | 99.0% | 400.06 | 100 MG
AN0128, a boron-containing antibacterial and anti-inflammatory agent | 872044-70-7 | 99.0% | 400.06 | 100 MG
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 25 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 25 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
Medchemexpress LLC Guanidine hydrochloride | 50-01-1 | 98.0% | 500 G
Guanidine hydrochloride (Guanidinium chloride) is a strong chaotrope and a potent denaturant of proteins, intended strictly for research purposes.
- Facilitates the refolding of acid-unfolded apomyoglobin and cytochrome c at low concentrations.
- Induces co-operative unfolding of the molten globule state at concentrations exceeding 1 M.
- Does not interfere with disulfide bonds, preserving ordered protein structure.
- Effective in causing the loss of the stable [PSI+] element from yeast cells at millimolar concentrations.
- A 5 mM concentration in growth media cures [PSI+] and other yeast prions.
- Markedly diminishes Hsp104-mediated basal and acquired thermotolerance.
- Impairs Hsp104's capacity to restore activity in thermally denatured luciferase.
- Significantly lowered the death rate of infant mice infected with coxsackievirus A16 in studies.
Apexbio Technology LLC MRTX-1133(Synonyms: MRTX1133, MRTX 1133, Mirati-1133, KRAS G12D inhibitor MRTX1133), 5mg, CAS: 2621928-55-8.
MRTX-1133 (CAS 2621928-55-8) is a non-covalent alkyne-based inhibitor specifically targeting the KRAS G12D mutant protein It binds KRAS G12D with sub-picomolar affinity occupying the Switch II pocket and forming multiple intermolecular interactions Through these interactions MRTX-1133 disrupts SOS1-mediated guanine nucleotide exchange and prevents the assembly of KRAS-GTP/RAF1 signaling complexes thereby inhibiting downstream KRAS-driven signaling pathways MRTX-1133 is applied in cancer biology research to investigate tumor signaling and therapeutic strategies involving KRAS G12D mutations
Medchemexpress LLC Clonidine hydrochloride | 4205-91-8 | 99.9% | 1 ML
Clonidine hydrochloride is an agonist of α2-adrenoceptor and a potent antihypertensive agent, primarily intended for research use. This specific product is a 10 mM solution in DMSO.
- Agonist of α2-adrenoceptor
- Potent antihypertensive agent
- For research use only
- High purity: 99.9%
- Induces CGRP mRNA expression in endothelial cells
- Increases NO level in endothelial cells
- Suppresses dopamine efflux in the prefrontal cortex
- Solution stable at -20°C for 1 month or -80°C for 6 months
Apexbio Technology LLC MYK-461 1642288-47-8 25mg
MYK-461 is a small-molecule inhibitor interacting directly with cardiac myosin heavy chain to modulate myocardial contraction It specifically reduces myocardial contractility through inhibition of cardiac myosin ATPase enzymatic activity thereby limiting myosin-mediated phosphate release without affecting ADP dissociation rates In rodent cardiomyocytes MYK-461 demonstrates dose-dependent reductions in fractional shortening and sarcomeric force generation without impacting calcium transient dynamics Its inhibitory potency against cardiac myosin ATPase surpasses that observed for skeletal muscle isoforms In preclinical hypertrophic cardiomyopathy mouse models MYK-461 administration attenuates cardiac contractile function facilitating investigations into myocardial contractility regulation and potential therapeutic strategies against hypertrophic cardiomyopathy
Sigma Aldrich Fine Chemicals Biosciences Agar ash 2.0 4.55KG
Agar is a polysaccharide consisting of - D-galactopyranosyl and 3 6-anhydro -L- galactopyranosyl units. Depending on the source agar exists as various substituted forms such as methyl and sulphate ether. It is a linear galactan polysaccharide isolated from the cell wall of Rhodophyceae class of seaweeds.
eMolecules 50-01-1 | Guanidine hydrochloride | Chem-Impex | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 1kg | 342450116
Guanidine hydrochloride | Chem-Impex | 50-01-1 | MFCD00013026 | 95.530 | CH6ClN3 | 99.000 | Cl.NC(N)=N | 1kg | 342450116
Sigma Aldrich Fine Chemicals Biosciences Guanidine hydrochloride solution, 6M Reagent designed and manufactured under cGMP controls suitable for use in an IVD application | 4L
Guanidine hydrochloride solution, 6M Reagent designed and manufactured under cGMP controls suitable for use in an IVD application | 4L
Medchemexpress LLC Steviol analytical standard | 471-80-7 | MFCD00210558 | >98.0% | 318.45 | C20H30O3 | 10 MG
Steviol is an analytical reference standard of the diterpene steviol, the primary metabolite of steviol glycosides, supplied for research and analytical applications. It is reported to inhibit AQP2 and CFTR and is provided in small laboratory pack sizes suitable for analytical work.
- Intended as an analytical reference standard for research and analysis.
- Primary metabolite of steviol glycosides.
- Reported inhibitor of AQP2 and CFTR (per supplier literature).
- Available in small laboratory pack sizes, including 10 mg.
- CAS number 471-80-7 and molecular formula C20H30O3.
- Supplied for use in analytical assays and method development.
eMolecules 1187927-45-2 | N-p-Tolyl-guanidine oxalate | J & W PharmLab, LLC | MFCD11506082 | 239.231 | C10H13N3O4 | 96.000 | OC(=O)C(O)=O.Cc1ccc(NC(N)=N)cc1 | 5g | 249978886
N-p-Tolyl-guanidine oxalate | J & W PharmLab, LLC | 1187927-45-2 | MFCD11506082 | 239.231 | C10H13N3O4 | 96.000 | OC(=O)C(O)=O.Cc1ccc(NC(N)=N)cc1 | 5g | 249978886
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 5 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 250 mL Glass (28-400)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 174.7 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C
eMolecules 192188-70-8 | Ambeed | 44-(14-Phenylenebis(ethyne-21-diyl))dibenzaldehyde | 100mg | 633659855 | A1226413 | 334.374 | C24H14O2
AstaTech | BIS[ALPHAALPHA-BIS(TRIFLUOROMETHYL)BENZENEMETHANOLATO]DIPHENYLSULFUR | 0.1g | 718062933 | D85638 | 95.000 | 32133-82-7 | MFCD00010662 | 672.530 | C30H20F12O2S
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