Carboximidamides
Medchemexpress LLC 6-methyl-2-((3-phenoxypropylamino)methyl)quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 | C20H22N2O2 | 50MG
UCSF924 is a potent and selective dopamine D4 receptor (DRD4) partial agonist used as a chemical probe in receptor pharmacology and neuropsychiatric research. It exhibits low-nanomolar activity (EC50 4.2 nM) and is supplied as a high-purity solid with recommended low-temperature storage for long-term stability.
- Potent DRD4 partial agonist (EC50 4.2 nM).
- High selectivity against other G protein-coupled receptors.
- Reported purity 99.53%.
- Molecular formula C20H22N2O2; molecular weight 322.40.
- Available in multiple pack sizes including 50 mg.
- Appearance: white to off-white solid; powder storage recommended at -20°C for long-term stability.
eMolecules 1321546-70-6 | Medchem Express | (S)-(-)-5-Fluorowillardiine (hydrochloride) | 10mg | 446267739 | HY-16713A | MFCD28385871 | 253.61 | C7H9ClFN3O4
Medchem Express | Chitinase-IN-1 | 5mg | 446269099 | HY-18598 | 1579991-61-9 | MFCD28385840 | 352.410 | C18H16N4O2S
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![eMolecules Pharmablock / 2-(1-bicyclo[2.2.2]octanyl)acetonitrile / 25mg / 586143188 / PB98198 / 0.000 / 34341-70-3 / [null] / 149.237 / C10H15N](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502452306.PNG-250.jpg)
eMolecules Pharmablock / 2-(1-bicyclo[2.2.2]octanyl)acetonitrile / 25mg / 586143188 / PB98198 / 0.000 / 34341-70-3 / [null] / 149.237 / C10H15N
Pharmablock / 2-(1-bicyclo[2.2.2]octanyl)acetonitrile / 25mg / 586143188 / PB98198 / 0.000 / 34341-70-3 / [null] / 149.237 / C10H15N
Medchemexpress LLC Fluorizoline | 25MG
Fluorizoline selectively and directly binds to prohibitin 1 (PHB1) and 2 (PHB2) and induces apoptosis Fluorizoline reduces chronic lymphocytic leukemia (CLL) cell viability through the upregulation of NOXA and BIM Fluorizoline exerts antitumor action in a p53-independent manner[1]
Medchemexpress LLC 6-methyl-2-((3-phenoxypropylamino)methyl)quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 g/mol | C20H22N2O2 | 25MG
UCSF924 is a potent, selective dopamine D4 receptor (DRD4) partial agonist research probe for neuropsychiatric and GPCR pharmacology studies. It exhibits an EC50 of 4.2 nM at DRD4 and shows no significant off-target activity across more than 320 non-olfactory GPCRs. The compound is provided as a solid with high purity suitable for in vitro assays.
- High potency at DRD4 (EC50 4.2 nM).
- Exceptional selectivity versus non-olfactory GPCRs (>320 tested).
- High purity (99.5%).
- Molecular weight 322.40 g/mol and formula C20H22N2O2.
- Available as a solid and as a 10 mM solution in DMSO for convenient use.
- Suitable for cell-based pharmacology and selectivity studies.
Alkali Scientific Guanidine Hydrochloride, 100 G
Guanidine Hydrochloride is a high-purity chaotropic agent commonly used in protein denaturation and nucleic acid isolation. This 100g sample is essential in disrupting protein structures for biochemical studies, facilitating the extraction of RNA, DNA, and proteins in molecular biology protocols. Its strong denaturing properties make it ideal for breaking down protein tertiary and quaternary structures, ensuring the efficient isolation of nucleic acids. It is also used in the preparation of buffers for experiments involving enzymatic activity and in studies of protein folding and structure. Guanidine Hydrochloride is indispensable in many molecular and biochemical laboratories.
Medchemexpress LLC AP39 | 1429061-80-2 | 96.4% | 721.77 | C37H38BrO2PS3 | 50MG
AP39 is a mitochondria-targeted hydrogen sulfide (H2S) donor used in biomedical research to modulate mitochondrial function and protect cells from oxidative damage. It elevates intracellular H2S levels, helps maintain mitochondrial DNA integrity, and has been investigated in models of ischemia-reperfusion injury and neurodegeneration. The compound is provided as a research-grade solid; follow recommended storage and handling conditions.
Alkali Scientific Guanidine Hydrochloride, 1 Kg
Guanidine Hydrochloride (1kg) is a high-purity reagent used in molecular biology for protein denaturation and nucleic acid isolation. This chaotropic agent is critical for unfolding proteins and disrupting their secondary, tertiary, and quaternary structures, making it essential for applications such as protein purification, enzyme studies, and nucleic acid extraction. It is particularly useful in preparing samples for electrophoresis and in isolating RNA and DNA from complex biological samples. Due to its strong denaturing properties, it also plays a role in the preparation of buffers for analytical and structural biology studies.
Medchemexpress LLC Smap-2 (DT-1154) | 1809068-70-9 | 99.5% | 5 MG
SMAP-2 (DT-1154) is a small-molecule, orally active activator of protein phosphatase 2A (PP2A) with demonstrated anti-cancer activity in preclinical studies. It is supplied as a white to off-white solid and includes manufacturer-reported solubility and storage guidance.
- Orally bioavailable PP2A activator with anticancer activity.
- High purity: 99.53% (manufacturer reported).
- Molecular weight 532.57; formula C27H27F3N2O4S.
- Soluble in DMSO (300 mg/mL); in vivo formulation guidance provided.
- Powder storage: -20°C (3 years) or 4°C (2 years); in solvent: -80°C (2 years).
eMolecules 349552-70-1 | Ambeed | Methyl 1-chloroisoquinoline-3-carboxylate | 250mg | 600840603 | A447479 | MFCD09863391 | 221.64 | C11H8ClNO2
Ambeed | 1-(35-Bis(trifluoromethyl)phenyl)-3-((1S2S)-2-(dimethylamino)cyclohexyl)thiourea | 1g | 525237516 | A751788 | 851477-20-8 | MFCD09834840 | 413.430 | C17H21F6N3S
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eMolecules AstaTech / TETRAKIS(DIMETHYLAMINO)ETHYLENE / 0.25g / 718059648 / F17451 / 95.000 / 996-70-3 / MFCD00009601 / 200.330 / C10H24N4
AstaTech / TETRAKIS(DIMETHYLAMINO)ETHYLENE / 0.25g / 718059648 / F17451 / 95.000 / 996-70-3 / MFCD00009601 / 200.330 / C10H24N4
eMolecules 164298-27-5 | Ambeed | 2-Fluoro-13-dimethylimidazolinium Hexafluorophosphate | 25g | 589771602 | A782641 | MFCD01863767 | 262.112 | C5H10F7N2P
Medchem Express | RBN-3143 | 5mg | 771358922 | HY-150207 | 2360853-16-1 | 449.540 | C22H28FN3O4S
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Medchemexpress LLC CCR4-351 | 2174938-70-4 | MFCD32701932 | 99.0% | C24H27Cl2N7O | 10MG
CCR4-351 is an orally active, potent, and selective chemokine receptor 4 (CCR4) antagonist for research use. It features a novel piperidinyl-azetidine motif and exhibits low-nanomolar activity in functional assays (reported IC50 ≈ 22 nM in calcium flux and ≈ 50 nM in CTX). The compound has shown antitumor activity in preclinical studies and is supplied at high purity for experimental applications.
- Potent CCR4 antagonist with low-nanomolar activity.
- Selective activity in CCR4 functional assays.
- Demonstrated antitumor activity in preclinical models.
- Suitable for in vitro and in vivo CCR4 pathway research.
- High purity (≈98.95%) for reliable experimental results.
Medchemexpress LLC Vitamin K3-d8 | 478171-80-1 | MFCD01317514 | 98.9% | 180.23 g/mol | C11D8O2 | 5 MG
Vitamin K3-d8 is a deuterium-labeled analogue of vitamin K3 (menadione) used as an internal standard and tracer for quantitative analytical methods. It is supplied as a small-quantity research reagent for method development and accurate quantification in NMR, GC-MS, and LC-MS workflows.
- Deuterium-labeled internal standard for vitamin K3
- Suitable for NMR, GC-MS, and LC-MS quantitative analysis
- Molecular formula C11D8O2; molecular weight 180.23 g/mol
- High purity (manufacturer lists ~98.9%)
- Supplied in small-mass quantities suitable for method development
- For research use only; not for human or clinical use