CYC-116 is a small-molecule research inhibitor of Aurora kinases A and B with low-nanomolar potency. It is used in biochemical and cellular studies to probe cell cycle regulation and antitumor activity, and exhibits additional activity against VEGFR2, Src, Lck, and FLT3.
- Potent inhibitor of Aurora A and B (Ki ≈ 8 and 9 nM).
- Additional kinase activity against VEGFR2, Src, Lck, and FLT3.
- Defined molecular formula and weight: C18H20N6OS, 368.46 g/mol.
- High reported purity (>99% by HPLC) suitable for research applications.
- Supplied in 100 mg research quantities for laboratory use.