Guanidine is a compound with a carbon atom bonded to two nitrogen atoms via singles bonds, and one nitrogen atom via double bond in the following formula: HNC(NH2)2. Guanidine can be considered the nitrogen analogue of carbonic acid.
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A cinnamic glycoside with antidepressant and neurotropic activities decreases immobility time in the forced swim test in rats at 0 26 mg/kg reduces chloral hydrate-induced sleep in mice
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Metformin hydrochloride (Metformin HCl CAS 1115-70-4) is a widely studied small molecule employed in biomedical research primarily for investigating glucose metabolism and type 2 diabetes mechanisms It acts through selective inhibition of hepatic gluconeogenesis without directly increasing insulin secretion The molecular targets include activation of AMP-activated protein kinase (AMPK) subsequently suppressing acetyl-CoA carboxylase (ACC) activity attenuating lipid biosynthesis and promoting fatty acid oxidation Additionally metformin inhibits mitochondrial glycerophosphate dehydrogenase (mGPD) changing cellular redox status and reducing lactate-driven gluconeogenesis pathways Key research applications of Metformin HCl include studies on glucose homeostasis metabolic disorders and AMPK signaling cascades
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Metformin (1 1-Dimethylbiguanide) a widely used drug for treatment of type 2 diabetes activates AMP-activated protein kinase (AMPK) in hepatocytes Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
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Metformin HCl (1 1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis) Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Metformin (1 1-Dimethylbiguanide) a widely used drug for treatment of type 2 diabetes activates AMP-activated protein kinase (AMPK) in hepatocytes Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More