Guanidines
Medchemexpress LLC PSB-1115 | 152529-79-8 | 99.0% | 350.35 g·mol⁻¹ | C14H14N4O5S | 100 MG
PSB-1115 is a selective A2B adenosine receptor antagonist used as a research tool to block A2B-mediated signaling in vitro and in vivo. It is reported to antagonize adenosine-mediated effects in animal models and to inhibit TNBS-induced responses.
- Selective A2B adenosine receptor antagonist for research use.
- High purity (99.0%) solid suitable for biological assays.
- Chemical formula C14H14N4O5S; molecular weight 350.35 g·mol⁻¹.
- Soluble in DMSO (100 mg/mL) and water (10 mg/mL) with sonication or warming.
- Recommended storage at -20°C; in solution, store at -80°C for long-term stability.
- Reported in vivo activity at 0.5 mg/kg (i.p.) in mouse mucociliary clearance studies.
Medchemexpress LLC Imidodicarbonimidic diamide, N-methyl-, hydrochloride (1:1) | 1674-62-0 | ≥97.0% | 151.60 | 100 MG
Metformin impurity 1 is a chemical product from MedChemExpress, identified by CAS number 1674-62-0 and molecular weight 151.60. It is intended for research use in laboratory settings.
- White to off-white solid appearance.
- Purity of at least 97.0%.
- Stable under recommended storage conditions.
- Melting point range of 148-151 °C.
- Recommended storage at 4°C, sealed, away from moisture and light.
- Harmful if swallowed.
- For research use only.
Medchemexpress LLC Metformin impurity 1 | 1674-62-0 | ≥97.0% | 151.60 | 500 MG
Metformin impurity 1 (Standard) is the analytical standard of Metformin impurity 1. This product is intended for research and analytical applications. The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
- Intended for research and analytical applications.
- Analytical standard, suitable for reference standard supplied assay.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC Biguanide | 56-03-1 | 98.1% | 100 MG
Biguanide is an orally active antihyperglycemic research reagent used to investigate mitochondrial metabolism and insulin signaling. It inhibits mitochondrial ATP production and activates the LKB1-AMPK pathway, altering cellular energy homeostasis.
- Used to study mitochondrial metabolism and AMPK signaling.
- Inhibits mitochondrial ATP production.
- Enhances insulin-receptor activation and downstream signaling.
- Typical purity 98.1% for research use.
- Provided as a solid suitable for in vitro and in vivo model studies.
Selleck Chemical LLC Metformin HCl S1950-1g
Metformin HCl (1 1-Dimethylbiguanide HCl) decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis) Metformin promotes mitophagy in mononuclear cells Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153
Sigma Aldrich Fine Chemicals Biosciences Metformin hydrochloride | 1115-70-4 | MFCD00012582 | 200 mg
Metformin hydrochloride | Mol Wt: 165.62 | 1115-70-4 | MFCD00012582 | 200 mg
Apexbio Technology LLC PSB 1115 152529-79-8 10mg
PSB 1115 is a selective antagonist targeting the human A2B adenosine receptor It is designed to inhibit receptor-mediated signaling pathways associated with adenosine receptors thereby regulating processes related to inflammation and immune response PSB 1115 exerts its biological activity primarily through antagonism of the A2B adenosine receptor In experimental studies PSB 1115 demonstrates inhibition of acetylcholine-induced contractions triggered by 2 4 6-trinitrobenzene sulfonic acid (TNBS) a commonly used method in gastrointestinal inflammation research Based on these pharmacological properties PSB 1115 holds research potential in investigating inflammatory response immune regulation and mechanisms underlying inflammation-related disorders
Apexbio Technology LLC Metformin HCl 1115-70-4 10g
Metformin hydrochloride (Metformin HCl CAS 1115-70-4) is a widely studied small molecule employed in biomedical research primarily for investigating glucose metabolism and type 2 diabetes mechanisms It acts through selective inhibition of hepatic gluconeogenesis without directly increasing insulin secretion The molecular targets include activation of AMP-activated protein kinase (AMPK) subsequently suppressing acetyl-CoA carboxylase (ACC) activity attenuating lipid biosynthesis and promoting fatty acid oxidation Additionally metformin inhibits mitochondrial glycerophosphate dehydrogenase (mGPD) changing cellular redox status and reducing lactate-driven gluconeogenesis pathways Key research applications of Metformin HCl include studies on glucose homeostasis metabolic disorders and AMPK signaling cascades
Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | MFCD32004449 | 99.4% | 374.82 g·mol⁻¹ | C17H19ClN6O2 | 10 MG
Zoniporide hydrochloride hydrate is the hydrochloride hydrate salt of zoniporide, a potent and selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE-1). It inhibits human NHE-1 with an IC50 of 14 nM and shows strong selectivity over other NHE isoforms, making it suitable for in vitro research on NHE-1-mediated pathways. Supplied as a high-purity solid for laboratory research.
- Potent NHE-1 inhibitor with an IC50 of 14 nM.
- Greater than 150-fold selectivity versus other NHE isoforms.
- High purity suitable for analytical and biological assays (purity reported 99.37%).
- Molecular weight 374.82 g·mol⁻¹.
- Available in small milligram pack sizes for research use.
Med Vet International Metformin Hcl (Generic Glucophage) Tablets 1000mg, 100 Tablets
Metformin HCl (Generic Glucophage) Tablets 1000mg, 100 tablets