Nitrogen mustard compounds
![eMolecules 19853-10-2 | 2-([1,1'-BIPHENYL]-2-YL)ACETONITRILE | AstaTech | MFCD00060294 | 193.249 | C14H11N | 98.000 | N#CCc1ccccc1-c1ccccc1 | 1g | 493153604](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502486047.JPG-250.jpg)
eMolecules 19853-10-2 | 2-([1,1'-BIPHENYL]-2-YL)ACETONITRILE | AstaTech | MFCD00060294 | 193.249 | C14H11N | 98.000 | N#CCc1ccccc1-c1ccccc1 | 1g | 493153604
2-([1,1'-BIPHENYL]-2-YL)ACETONITRILE | AstaTech | 19853-10-2 | MFCD00060294 | 193.249 | C14H11N | 98.000 | N#CCc1ccccc1-c1ccccc1 | 1g | 493153604
Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | 340.39 g/mol | C20H21FN2O2 | 5 MG
HN37 is a small-molecule research compound that functions as a potent activator of the KCNQ2 potassium channel. It contains an alkyne moiety suitable for click-chemistry derivatization and is intended for in vitro pharmacology and chemical biology applications.
- Potent KCNQ2 activation with EC50 of 37 nM.
- Alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition.
- High reported purity for reproducible assay performance.
- Soluble in DMSO at 50 mg/mL for preparation of concentrated stocks.
- Available in multiple milligram quantities for research use.
Medchemexpress LLC Rv01 | 1016897-10-1 | 98.1% | 263.29 g/mol | C17H13NO2 | 50MG
RV01 is a resveratrol analogue that inhibits aldehyde dehydrogenase (ALDH) activity and reduces ethanol-induced ALDH2 mRNA expression. Supplied as a solid research compound for in vitro biochemical and cellular studies, it has documented solubility in DMSO and defined storage/stability conditions.
![Medchemexpress LLC 5-amino-N-(3-fluoro-4-methoxybenzyl)-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide | 1451994-10-7 | 99.3% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234776.png-250.jpg)
Medchemexpress LLC 5-amino-N-(3-fluoro-4-methoxybenzyl)-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide | 1451994-10-7 | 99.3% | 50 MG
VU0467485 (AZ13713945) is a potent, selective, orally bioavailable positive allosteric modulator of the muscarinic acetylcholine receptor M4, provided as a research reagent for receptor pharmacology and preclinical studies.
- Potent and selective M4 positive allosteric modulator.
- Orally bioavailable properties support in vivo evaluation.
- High purity suitable for pharmacological assays.
- Available in multiple pack sizes, including 50 mg.
- Commonly used for studies of M4 signaling and antipsychotic-like activity in preclinical models.
![Medchemexpress LLC 4-(5-fluoro-1H-benzo[d]imidazol-2-yl)-N,N-dimethylaniline | 1458664-10-2 | MFCD20720876 | 99.6% | 255.29 | C15H14FN3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222052.png-250.jpg)
Medchemexpress LLC 4-(5-fluoro-1H-benzo[d]imidazol-2-yl)-N,N-dimethylaniline | 1458664-10-2 | MFCD20720876 | 99.6% | 255.29 | C15H14FN3 | 5 MG
β-catenin-IN-2 (Compound H1B1) is a small-molecule β-catenin inhibitor for research use, reported as a pink to red solid with high purity. It is characterized by molecular formula C15H14FN3 and a molecular weight of 255.29 g/mol, and is used in studies of colorectal cancer and β-catenin pathway biology.
- Potent β-catenin inhibitor for colorectal cancer research.
- Molecular formula C15H14FN3.
- Molecular weight 255.29 g/mol.
- Appearance: pink to red solid.
- Purity around 99.6% by HPLC.
- Available in small milligram-scale packages for laboratory studies.
- Typically prepared and handled in solution (DMSO) for assays.
![STA Pharmaceutical 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 10 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502344467.PNG-250.jpg)
STA Pharmaceutical 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 10 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N
3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 875211-10-2
- MDL: No data
- InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N
- Molecular Weight: 417.505
- Molecular Formula: C26H27NO4
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid
- SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O
eMolecules 1122-54-9 | 4-Acetylpyridine | Ambeed | MFCD00006433 | 121.139 | C7H7NO | 98.000 | CC(=O)c1ccncc1 | 10g | 490549457
4-Acetylpyridine | Ambeed | 1122-54-9 | MFCD00006433 | 121.139 | C7H7NO | 98.000 | CC(=O)c1ccncc1 | 10g | 490549457
Selleck Chemical LLC Bendamustine HCl 100mg 3543-75-7 SDX-105 (Cytostasane) HCl
Bendamustine (SDX-105, Cytostasane) HCl is a DNA-damaging agent with IC50 of 50 ?M in cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Epoxymicheliolide | 1343403-10-0 | MFCD28387434 | 99.8% | 264.32 g·mol-1 | C15H20O4 | 10 MG
Epoxymicheliolide is a micheliolide-derived small molecule supplied for research use. It is characterized by CAS 1343403-10-0, molecular formula C15H20O4, and a molecular weight of 264.32 g·mol-1. The compound is provided at high purity and is intended for biochemical and cellular studies; documentation such as COA, SDS, and a product datasheet are available to support use and safety.
- High purity suitable for research (>99.8%).
- Supplied in small milligram quantities for laboratory experiments.
- Characterized by CAS 1343403-10-0 and formula C15H20O4.
- Documentation available: COA, SDS, and product datasheet.
eMolecules 1246998-10-6 | 2-(Pentafluorosulfur)aniline | J&W PharmLab LLC | MFCD21362226 | 219.170 | C6H6F5NS | 96.000 | Nc1ccccc1S(F)(F)(F)(F)F | 50mg | 722712393
2-(Pentafluorosulfur)aniline | J&W PharmLab LLC | 1246998-10-6 | MFCD21362226 | 219.170 | C6H6F5NS | 96.000 | Nc1ccccc1S(F)(F)(F)(F)F | 50mg | 722712393
Medchemexpress LLC 1-(2-chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 | 00-00-0 | 99.0% | 253.72 | C9H12D4ClN3O3 | 5 MG
Deuterium-labeled trans-4'-Hydroxy CCNU Lomustine-d4 is a research-grade labeled analogue of trans-4'-Hydroxy lomustine intended for use as a tracer and internal standard in quantitative analytical methods. The product is supplied as a high-purity solid in a 5 MG vial and requires cold storage to maintain stability.
- Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS.
- High purity (99.0%).
- Solid, white to off-white appearance.
- Suitable as a tracer for pharmacokinetic and metabolic studies.
- Powder storage: -20°C for long-term stability; in solvent: -80°C for short-term stability.
- Supplied as a 5 MG vial for laboratory use.
Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | 100 MG
ZL0580, a structurally close analog of ZL0590, induces epigenetic suppression of HIV via selectively binding to BD1 domain of BRD4. It induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.
- Induces epigenetic suppression of HIV
- Selectively binds to BD1 domain of BRD4
- Inhibits Tat transactivation and transcription elongation
- Induces repressive chromatin structure at the HIV promoter
- Suppresses HIV in primary CD4+ T cells
- Exhibits low toxicity in cell viability assays
Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | C20H21FN2O2 | 50 MG
HN37 is a potent and chemically stable antiepileptic agent candidate with an EC50 of 37 nM for KCNQ2. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In vitro, HN37 is a potent neuronal Kv7 activator with subtype selectivity similar to RTG.
- Potent and chemically stable antiepileptic agent candidate
- EC50 of 37 nM for KCNQ2
- Click chemistry reagent with an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Potent neuronal Kv7 activator with subtype selectivity similar to RTG
Medchemexpress LLC 1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 | 56239-24-8 | 99.0% | C9H12D4ClN3O3 | 1 MG
trans-4'-Hydroxy CCNU Lomustine-d4 is a deuterium-labeled compound, primarily used as a tracer or as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes, like deuterium, into drug molecules serves as a critical method for quantitation during drug development, with the potential to influence pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Toringin | 1329-10-8 | 5 MG
Toringin is a bioflavonoid isolated from the bark of Docyniopsis tschonoski. It decreases the cis-effect of expanded CTG repeats and cytotoxicity, and rescues PC12 neuronal cells when exposed to isosakuranetin. As a flavonoid, Toringin exhibits various biological activities beneficial against conditions such as cancers and coronary heart disease, and is effective in ameliorating RNA gain of function caused by expanded CTG repeats.
- Decreases cis-effect of expanded CTG repeats
- Decreases cytotoxicity
- Rescues PC12 neuronal cells
- Ameliorates RNA gain of function
- Exhibits various biological activities
- Beneficial against cancers and coronary heart disease