Nitrogen mustard compounds
eMolecules 213211-10-0 | Medchem Express | BIRT 377 | 5mg | 758391260 | HY-110117 | MFCD28166481 | 442.13 | C18H15BrCl2N2O2
Medchem Express | Isoorientin | 1mg | 446275345 | HY-N0767 | 4261-42-1 | MFCD00017433 | 448.380 | C21H20O11
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Sigma Aldrich Fine Chemicals Biosciences Cyclophosphamide monohydrate ISOPAC, 6055-19-2, MFCD00149395
Cyclophosphamide monohydrate ISOPAC
Medchemexpress LLC β-catenin-IN-2 | 1458664-10-2 | 99.6% | C15H14FN3 | 10MG
β-catenin-IN-2 (Compound H1B1) is a small-molecule inhibitor of β-catenin intended for preclinical research, particularly studies of colorectal cancer and Wnt/β-catenin signaling. The compound is characterized by CAS 1458664-10-2, molecular formula C15H14FN3, molecular weight 255.29, and is supplied with analytical documentation for research use.
- Potent β-catenin inhibitor suitable for cellular and biochemical assays.
- Reported applicability in colorectal cancer research.
- High purity (99.6%) for reliable experimental results.
- Characterized with COA, HNMR, and LCMS data available.
- Small-molecule properties: molecular weight 255.29, formula C15H14FN3.
Medchemexpress LLC Mizagliflozin | 666843-10-3 | 99.2% | 564.67 | 100 MG
Mizagliflozin, also known by its synonyms DSP-3235 free base, KGA-3235 free base, and GSK-1614235 free base, is a highly potent and orally active compound primarily recognized as a selective inhibitor of SGLT1 (sodium-glucose cotransporter 1). Its inhibitory constant (Kᵢ) against human SGLT1 is 27 nM, showcasing a remarkable selectivity profile with 303-fold greater potency for SGLT1 compared to SGLT2. This selectivity makes it a promising antidiabetic agent, as it can effectively modify postprandial blood glucose excursion, helping to manage blood sugar levels after meals. Beyond its antidiabetic properties, Mizagliflozin has also demonstrated potential in alleviating chronic constipation, exhibiting a laxative effect in animal models.
- Potent and selective SGLT1 inhibitor
- Orally active compound
- Modifies postprandial blood glucose excursion
- Potential in ameliorating chronic constipation
Selleck Chemical LLC Camonsertib-E1108-5MG
Camonsertib is a highly potent and selective inhibitor of ATR kinase with an IC50 of 1 nM
Medchemexpress LLC Mizagliflozin | 666843-10-3 | 99.2% | 564.67 | 50 MG
Mizagliflozin (DSP-3235 free base) is a potent, orally active, and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. It displays 303-fold selectivity over SGLT2. This compound functions as an antidiabetic agent capable of modifying postprandial blood glucose excursion and also shows potential in the amelioration of chronic constipation. In vivo, the compound at doses of 3-30 mg/kg orally has a laxative effect, increasing fecal wet weight in a rat model of low-fiber-diet-induced constipation. The compound has a short half-life, with 0.23 h after intravenous administration and 1.14 h after oral administration.
- Highly selective SGLT1 inhibitor
- Helps manage postprandial blood glucose levels
- Potential to treat chronic constipation
- Orally active for convenient administration
Sigma Aldrich Fine Chemicals Biosciences Bis(2-chloroethyl)amine hydrochloride 98% | 821-48-7 | MFCD00012515 | 100G
Bis(2-chloroethyl)amine hydrochloride 98% | Purity: 98% | Mol Wt: 178.49 | 821-48-7 | MFCD00012515 | 100G
eMolecules 52591-10-3 | Medchem Express | Iriflophenone | 5mg | 532150258 | HY-N4010 | MFCD20260852 | 246.218 | C13H10O5
Medchem Express | Iriflophenone | 5mg | 532150258 | HY-N4010 | 52591-10-3 | MFCD20260852 | 246.218 | C13H10O5
Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | 98.0% | 206.99 g/mol | C4H9Cl2O3P | 100 MG
2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used primarily as an intermediate in organic synthesis and building-block chemistry. It has molecular formula C4H9Cl2O3P and a molecular weight of 206.99 g/mol. Typical applications include incorporation into multi-step syntheses; quality attributes such as purity and recommended storage should be confirmed from the certificate of analysis.
eMolecules 75390-44-2 | Ambeed | 4-Phenylthiazole-2-carbaldehyde | 100mg | 595927454 | A503314 | MFCD02665589 | 189.23 | C10H7NOS
Ambeed | 4-Phenylthiazole-2-carbaldehyde | 100mg | 595927454 | A503314 | 75390-44-2 | MFCD02665589 | 189.230 | C10H7NOS
Medchemexpress LLC Tas4464 | 1848959-10-3 | 99.2% | 10 MG
TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) with an IC50 of 0.955 nM. This compound inhibits cullin neddylation, leading to the accumulation of CRL substrates such as CDT1, p27, and phosphorylates IκBα in various human cancer cell lines.
- Highly potent and selective inhibitor of NEDD8 activating enzyme (NAE)
- Inhibits cullin neddylation
- Induces accumulation of CRL substrates such as CDT1, p27, and phosphorylates IκBα in 47 human cancer cell lines
eMolecules 1801-10-1 | 3-(Trifluoromethyl)benzamide | Ambeed | MFCD00014802 | 189.137 | C8H6F3NO | 98.000 | NC(=O)c1cccc(c1)C(F)(F)F | 1mg | 761204476
3-(Trifluoromethyl)benzamide | Ambeed | 1801-10-1 | MFCD00014802 | 189.137 | C8H6F3NO | 98.000 | NC(=O)c1cccc(c1)C(F)(F)F | 1mg | 761204476
Medchemexpress LLC Senkyunolide A | 63038-10-8 | MFCD16660665 | 99.3% | 192.26 g/mol | C12H16O2 | 10 MG
Senkyunolide A is a phthalide-class natural product supplied as a research-grade analytical standard, reported to have anticancer and neuroprotective activities and commonly used in biochemical and cellular studies.
- High purity (~99.3%), suitable for analytical and biological research.
- Molecular formula C12H16O2, molecular weight 192.26 g/mol.
- Available in small research quantities (e.g., 10 MG) for lab-scale experiments.
- Appearance: colorless to light yellow liquid; density ~1.1 g/cm3.
- Storage: store at -80°C, protect from light, under inert gas when required.
eMolecules 3302-10-1 | 3,5,5-Trimethylhexanoicacid | Ambeed | MFCD00020507 | 158.241 | C9H18O2 | 98.000 | CC(CC(O)=O)CC(C)(C)C | 100g | 624121817
3,5,5-Trimethylhexanoicacid | Ambeed | 3302-10-1 | MFCD00020507 | 158.241 | C9H18O2 | 98.000 | CC(CC(O)=O)CC(C)(C)C | 100g | 624121817
Medchemexpress LLC β-catenin-IN-2 | 1458664-10-2 | 99.6% | 255.29 | 50 MG
β-catenin-IN-2 is a potent β-catenin inhibitor, also known as Compound H1B1. It is utilized in the study of colorectal cancer, where it suppresses the transcriptional activity of β-catenin/Tcf-4 in HCT116 cells in a dose-dependent manner at concentrations of 10-40 μM.
- Solid appearance with pink to red color
- High purity of 99.6%
- Molecular weight of 255.29
- Formula: C15H14FN3
- Inhibits β-catenin/Tcf-4 transcriptional activity
- Used in colorectal cancer research