Oximes
Invitrogen™ GeneArt™ Gibson Assembly HiFi Cloning Kit, chemically competent cells
The GeneArt Gibson Assembly HiFi Cloning Kit enables DNA assembly and cloning via a technique that allows multiple overlapping DNA fragments to be seamlessly linked in a one-step, 15-60 minute isothermal reaction.
BIOHIPPO Syn-JYCamP1s-Puro LV
Syn-JYCamP1s-Puro is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
BIOHIPPO Syn-JGCamP7b-Puro LV
Syn-JGCamP7b-Puro is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Apexbio Technology LLC 2,3-Butanedione-2-monoxime 57-71-6 100g
2 3-Butanedione-2-monoxime (BDM CAS 57-71-6) is a small molecule inhibitor of myosin ATPase activity By interfering with the ATP-driven cross-bridge cycling of myosin BDM disrupts the conversion of chemical energy into mechanical force impacting cytoskeletal dynamics In vitro studies have shown that treatment with BDM in fission yeast leads to reduced cell size increased septation and altered actin organization though cytokinetic actin ring formation is maintained BDM is widely employed as a reversible probe of myosin function in muscle and cell biology research to elucidate contractile mechanisms and cytoskeletal behaviors
Apexbio Technology LLC 2,3-Butanedione-2-monoxime 57-71-6 10mM (in 1mL DMSO)
2 3-Butanedione-2-monoxime (BDM CAS 57-71-6) is a small molecule inhibitor of myosin ATPase activity By interfering with the ATP-driven cross-bridge cycling of myosin BDM disrupts the conversion of chemical energy into mechanical force impacting cytoskeletal dynamics In vitro studies have shown that treatment with BDM in fission yeast leads to reduced cell size increased septation and altered actin organization though cytokinetic actin ring formation is maintained BDM is widely employed as a reversible probe of myosin function in muscle and cell biology research to elucidate contractile mechanisms and cytoskeletal behaviors
Medchemexpress LLC Taraxerol | 127-22-0 | 5 MG
Taraxerol is an anti-inflammatory and anti-cancer agent isolated from Taraxacum mongolicum. It attenuates acute inflammation by inhibiting the NF-κB signaling pathway and also induces cell apoptosis.
- Isolated from Taraxacum mongolicum
- Attenuates acute inflammation by inhibiting the NF-κB signaling pathway
- Induces cell apoptosis
- Appears as a solid, white to yellow color
- Soluble in THF (10 mg/mL with ultrasonic), insoluble or slightly soluble in DMSO, and insoluble in H2O
- Purity is 98.0%
Apexbio Technology LLC ACETOPHENONE-500MG
Acetophenone (CAS No 98-86-2) is a versatile compound often employed in biomedical research particularly in pharmacological and toxicological studies Originating as a simple aromatic ketone it serves as a precursor in the metabolism of various pharmaceuticals Its action mechanism involves multiple targets including signaling pathways related to neural and enzymatic activities In vitro acetophenone demonstrates activity in the nanomolar to low micromolar range making it effective in modulating cellular responses It is frequently used in applications involving cell models like neuronal and liver cells as well as in animal studies for drug screening Experimental concentrations typically depend on the specific research design Acetophenone s ability to interact with diverse biological systems underlines its role as a critical tool in the study of drug actions and metabolic pathways
Medchemexpress LLC Taraxerol | 127-22-0 | MFCD13186859 | 98.0% | 426.72 g·mol⁻¹ | C30H50O | 10 MG
Taraxerol is a naturally occurring pentacyclic triterpenoid reported to have anti-inflammatory and anticancer activity. It attenuates acute inflammation by inhibiting NF-κB signaling and can induce apoptosis in cellular models. Supplied as a high-purity research reagent for laboratory use.
- Natural pentacyclic triterpenoid with anti-inflammatory and anticancer activity.
- Inhibits NF-κB signaling and can induce apoptosis in cells.
- High purity (typical 98.0%; batch COA may report higher).
- Supplied in small research pack sizes suitable for biochemical and cell studies.
- Soluble in common organic solvents such as DMSO and THF.
- Intended for laboratory research use only.
Apexbio Technology LLC ACETOPHENONE-1G
Acetophenone (CAS No 98-86-2) is a versatile compound often employed in biomedical research particularly in pharmacological and toxicological studies Originating as a simple aromatic ketone it serves as a precursor in the metabolism of various pharmaceuticals Its action mechanism involves multiple targets including signaling pathways related to neural and enzymatic activities In vitro acetophenone demonstrates activity in the nanomolar to low micromolar range making it effective in modulating cellular responses It is frequently used in applications involving cell models like neuronal and liver cells as well as in animal studies for drug screening Experimental concentrations typically depend on the specific research design Acetophenone s ability to interact with diverse biological systems underlines its role as a critical tool in the study of drug actions and metabolic pathways
Apexbio Technology LLC Indirubin-3'-oxime 160807-49-8 50mg
Indirubin-3 -oxime (CAS 160807-49-8) is a derivative of indirubin investigated primarily as an inhibitor of glycogen synthase kinase-3 (GSK-3 ) exhibiting an IC50 of approximately 22 nM This compound also inhibits CDK5/p25 and CDK1/cyclin B with IC50 values of around 100 nM and 180 nM respectively while demonstrating weaker inhibitory activity against 5-lipoxygenase (IC50 7 8 10 M) Due to its modulation of multiple kinases involved in cell signaling Indirubin-3 -oxime is widely utilized in research on cellular signaling pathways and the molecular mechanisms underlying disease
Apexbio Technology LLC Indirubin-3'-oxime 160807-49-8 5mg
Indirubin-3 -oxime (CAS 160807-49-8) is a derivative of indirubin investigated primarily as an inhibitor of glycogen synthase kinase-3 (GSK-3 ) exhibiting an IC50 of approximately 22 nM This compound also inhibits CDK5/p25 and CDK1/cyclin B with IC50 values of around 100 nM and 180 nM respectively while demonstrating weaker inhibitory activity against 5-lipoxygenase (IC50 7 8 10 M) Due to its modulation of multiple kinases involved in cell signaling Indirubin-3 -oxime is widely utilized in research on cellular signaling pathways and the molecular mechanisms underlying disease
Medchemexpress LLC Indirubin-3′-oxime | 667463-82-3 | 99.1% | 277.28 | 25 MG
Indirubin-3′-oxime (IDR3O) is a synthetic derivative of indirubin that functions as a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). It directly inhibits all three isoforms of JNK (JNK1, JNK2, and JNK3). This compound also promotes height growth through the activation of Wnt/β-catenin signaling in chondrocytes and is intended for research use only.
- Potent inhibitor of cyclin-dependent kinases (CDKs)
- Potent inhibitor of glycogen synthase kinase 3β (GSK3β)
- Directly inhibits JNK1 (IC50: 0.8 μM), JNK2 (IC50: 1.4 μM), and JNK3 (IC50: 1.0 μM)
- Enhances height growth by activating Wnt/β-catenin signaling in chondrocytes
- Blocks c-Jun phosphorylation in cerebellar granule neurons (CGNs)
- Prevents 6OHDA-induced decrease of nuclear localized MEF2D expression in PC12 cells
- Enhances tibial longitudinal growth in mice
- For research use only