Quaternary ammonium salts
Medchemexpress LLC L-Carnitine | 541-15-1 | MFCD00038747 | 100.0% | 50 G
L-Carnitine, also known as (R)-Carnitine or Levocarnitine, is a highly polar, small zwitterion that serves as an essential co-factor for the mitochondrial β-oxidation pathway. Its primary function involves transporting long-chain fatty acyl-CoAs into the mitochondria for degradation through β-oxidation. L-Carnitine also acts as an antioxidant and has demonstrated the ability to ameliorate metabolic imbalances in various inborn errors of metabolism. This product is intended for research use only.
- Essential co-factor for mitochondrial β-oxidation
- Transports long-chain fatty acyl-CoAs into mitochondria
- Acts as an antioxidant
- Ameliorates metabolic imbalances
- For research use only
Medchemexpress LLC 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, bromide (1:2) | 55-97-0 | 99.9% | 25 G
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) with mixed competitive and noncompetitive activity. It possesses anti-hypertensive properties and has been shown to attenuate sympathetic activity and blood pressure in spontaneously hypertensive animal models.
- Non-selective ganglionic nicotinic-receptor antagonist (nAChR)
- Exhibits mixed competitive and noncompetitive activity
- Attenuates sympathetic activity and blood pressure
- Targets apoptosis, cardiovascular disease, and neurological disease
- Appears as a white to off-white solid
Medchemexpress LLC Hexamethonium Bromide | 55-97-0 | MFCD00011787 | 50 G
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) that exhibits both competitive and noncompetitive activity. It possesses anti-hypertensive properties and has been shown to attenuate sympathetic activity and blood pressure in spontaneously hypertensive animal models.
- Non-selective ganglionic nicotinic-receptor antagonist (nAChR)
- Features both competitive and noncompetitive activity
- Exhibits anti-hypertensive activity
- Attenuates sympathetic activity and blood pressure in animal models
- Targeted towards nAChR and apoptosis
- Relevant for cardiovascular and neurological disease research
Medchemexpress LLC Hexamethonium Bromide | 55-97-0 | 99.91% | 5 G
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor (nAChR) antagonist, exhibiting both competitive and noncompetitive activity. It possesses anti-hypertensive properties and has been shown to reduce sympathetic activity and blood pressure in animal models of spontaneous hypertension.
- Non-selective ganglionic nicotinic-receptor antagonist
- Demonstrates mixed competitive and noncompetitive activity
- Exhibits anti-hypertensive activity
- Attenuates sympathetic activity
- Reduces blood pressure in spontaneously hypertensive animal models
Medchemexpress LLC Hexamethonium bromide | 55-97-0 | MFCD00008323 | 99.9% | 1 G
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor (nAChR) antagonist with mixed competitive and noncompetitive activity. It possesses anti-hypertensive activity and has been shown to attenuate sympathetic activity and blood pressure in spontaneously hypertensive animal models.
- Non-selective ganglionic nicotinic-receptor antagonist (nAChR)
- Mixed competitive and noncompetitive activity
- Anti-hypertensive activity
- Attenuates sympathetic activity and blood pressure in spontaneously hypertensive animal models
Medchemexpress LLC Hexamethonium Bromide | 55-97-0 | MFCD00011787 | 99.9% | 10 G
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) with mixed competitive and noncompetitive activity. It also exhibits anti-hypertensive activity and can attenuate sympathetic activity and blood pressure in spontaneously hypertensive animal models.
- Target: nAChR (nicotinic-receptor)
- Research areas: Apoptosis, cardiovascular disease, neurological disease
- Publications verification: 4 publications verification
Apexbio Technology LLC Hexamethonium Bromide 55-97-0 5g
Hexamethonium Bromide (CAS 55-97-0) is a bis-quaternary ammonium compound that acts as a selective antagonist of neuronal nicotinic acetylcholine receptors (nAChRs) located in autonomic ganglia By competitively inhibiting synaptic transmission at these receptors Hexamethonium Bromide effectively blocks ganglionic neurotransmission without significant effects on muscarinic receptors or neuromuscular junctions This property makes it a valuable tool in pharmacological studies investigating autonomic nervous system function and the physiological roles of ganglionic nAChRs in various experimental models
Apexbio Technology LLC Decamethonium Bromide 541-22-0 10g
Decamethonium Bromide (CAS 541-22-0) is a bis-quaternary ammonium compound targeting nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction It is designed to bind and activate muscle-type nAChRs thereby inducing sustained depolarization and neuromuscular blockade Decamethonium Bromide exerts its biological activity primarily through partial agonist-mediated depolarization block of these receptors preventing normal muscle contractions Based on these pharmacological properties Decamethonium Bromide holds research potential in the evaluation of neuromuscular blockers and in studies elucidating receptor-channel function in neuromuscular transmission
Apexbio Technology LLC Decamethonium Bromide 541-22-0 10mM (in 1mL DMSO)
Decamethonium Bromide (CAS 541-22-0) is a bis-quaternary ammonium compound targeting nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction It is designed to bind and activate muscle-type nAChRs thereby inducing sustained depolarization and neuromuscular blockade Decamethonium Bromide exerts its biological activity primarily through partial agonist-mediated depolarization block of these receptors preventing normal muscle contractions Based on these pharmacological properties Decamethonium Bromide holds research potential in the evaluation of neuromuscular blockers and in studies elucidating receptor-channel function in neuromuscular transmission
Medchemexpress LLC Decamethonium Bromide | 541-22-0 | MFCD00011779 | ≥98.0% | 5 G
Decamethonium Bromide is an acetylcholine receptor inhibitor and muscle relaxant. It acts as a nicotinic AChR partial agonist and neuromuscular blocking agent, inducing depolarization of skeletal muscles. It binds to postsynaptic acetylcholine receptors, leading to persistent paralysis and is used in anesthesia to induce paralysis.
- Acetylcholine receptor inhibitor and muscle relaxant
- Functions as a nicotinic AChR partial agonist
- Acts as a neuromuscular blocking agent
- Targets nAChR
- Induces depolarization of skeletal muscles
- Binds to postsynaptic acetylcholine receptors causing persistent paralysis
- For research use only
- Used in anesthesia to induce paralysis
Medchemexpress LLC Decamethonium Bromide | 541-22-0 | MFCD00011779 | 98.7% | 1 ML
Decamethonium Bromide is an acetylcholine receptor inhibitor and muscle relaxant. It functions by inducing depolarization of skeletal muscles and subsequently binding to postsynaptic acetylcholine receptors, leading to persistent paralysis. For research use only.
- Acetylcholine receptor inhibitor
- Muscle relaxant
- Induces depolarization of skeletal muscles
- Binds to postsynaptic acetylcholine receptors to induce persistent paralysis
Medchemexpress LLC MDEG-541 | 98.1% | 674.83 g·mol⁻¹ | C35H38N4O6S2 | 10 MG
MDEG-541 is a PROTAC small-molecule degrader that targets the MYC-MAX dimerization complex and exhibits antiproliferative activity by reducing cellular levels of MYC, GSPT1, GSPT2, and PLK1. It is provided as a research reagent with reported physicochemical characterization and recommended storage conditions.
- Potent MYC-MAX degrader with PROTAC mechanism of action.
- Demonstrates antiproliferative activity and downregulates MYC, GSPT1, GSPT2, and PLK1.
- High reported purity suitable for research applications (≈98.1%).
- Supplied in small research quantities for biochemical and cellular studies.
- Stable as powder when stored at -20°C; follow solvent storage guidelines for dissolved material.