Quaternary ammonium salts

Ammonium salts in which a nitrogen atom (with a +1 formal charge) has four carbon-nitrogen single bonds; this nitrogen could be bonded to four functional groups containing carbon.

451 – 465 of 749 results

451

Cayman Chemical cIs-VaccenIc AcId-d13 5mg

A ferroptosis inhibitor and a derivative of ferrostatin-1 inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells (EC50 6 nM) inhibits iron-induced cell death in isolated mouse kidney proximal tubules at 2 UM protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia at 100 nM increases survival of medium spiny neurons in rat corticostriatal brain slices in an in vitro model of Huntingtons disease increases production of ROS in L major promastigotes at 3 UM is toxic to L major promastigotes (LD50 3 34 UM)

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452

Cayman Chemical trns-VaccenIc AcId-d13 10mg

An orally bioavailable inhibitor of mitochondrial complex I inhibits the ubiquinone reduction activity of isolated murine mitochondrial complex I at 60 nM reduces basal and spare respiratory capacities and increases glycolytic flux in primary CLL cells at 100 nM induces apoptosis in CLL cells grown under low glucose conditions or when administered in combination with 2-deoxy-D-glucose induces tumor regression in a glycolysis-deficient NB1 mouse xenograft model when administered at doses of 5 and 10 mg/kg

Pricing & Availability

453

Cayman Chemical CholIc AcId 100g

A potent inhibitor of the kinase activity of ALK2 (IC50 13-108 nM) disrupts dorsoventral development in zebrafish affects stem cell development increasing cardiomyocyte progenitors and promoting neurogenesis inhibits the growth of lung cancer cells reducing tumor growth in a xenograft model