Quaternary ammonium salts
Cayman Chemical cIs-VaccenIc AcId-d13 1mg
A ferroptosis inhibitor and a derivative of ferrostatin-1 inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells (EC50 6 nM) inhibits iron-induced cell death in isolated mouse kidney proximal tubules at 2 UM protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia at 100 nM increases survival of medium spiny neurons in rat corticostriatal brain slices in an in vitro model of Huntingtons disease increases production of ROS in L major promastigotes at 3 UM is toxic to L major promastigotes (LD50 3 34 UM)
Cayman Chemical cIs-VaccenIc AcId-d13 5mg
A ferroptosis inhibitor and a derivative of ferrostatin-1 inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells (EC50 6 nM) inhibits iron-induced cell death in isolated mouse kidney proximal tubules at 2 UM protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia at 100 nM increases survival of medium spiny neurons in rat corticostriatal brain slices in an in vitro model of Huntingtons disease increases production of ROS in L major promastigotes at 3 UM is toxic to L major promastigotes (LD50 3 34 UM)