Organic disulfides
Medchemexpress LLC (R)-Zelebrudomide ((R)-NX-2127) | 3024312-52-2 | C39H45N9O5 | 50 MG
(R)-Zelebrudomide ((R)-NX-2127), also known as (R)-Compound 28, is an isomer of the BTK PROTAC degrader Zelebrudomide. It is intended for research use only.
- Molecular weight: 719.83
- Chemical formula: C39H45N9O5
- Appearance: Solid
- Color: Light yellow to yellow
- Purity: 98.93%
- Shipping condition: Room temperature in continental US
- Storage condition: 4°C, protect from light
- Storage in solvent: -80°C for 6 months; -20°C for 1 month, protect from light
Medchemexpress LLC Zelebrudomide (NX-2127) | 2416131-46-7 | C39H45N9O5 | 100 MG
Zelebrudomide (NX-2127) is an orally active PROTAC degrader that targets Bruton's Tyrosine Kinase (BTK). It inhibits the proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib. Zelebrudomide also catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with respective values of 25 nM and 54 nM. Additionally, it stimulates T cell activation and increases IL-2 production in primary human T Cells.
- Orally active PROTAC degrader targets Bruton's Tyrosine Kinase (BTK).
- Inhibits proliferation of BTKC481S mutant TMD8 cells more effectively than Ibrutinib.
- Catalyzes degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with respective values of 25 nM and 54 nM.
- Stimulates T cell activation and increases IL-2 production in primary human T Cells.
- Demonstrates potent degradation of BTK in vivo.
- Results in superior tumor growth inhibition in both WT TMD8 and C481S mutant xenograft models in mice.
Medchemexpress LLC HY-100216 500mg Medchemexpress, SPDP CAS:68181-17-9 Purity:>98%
Medchemexpress, HY-100216 500mg SPDP CAS:68181-17-9 SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls [1] [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cambridge Isotope Laboratories Dicyclohexyl phthalate (unlabeled) 100 ug/mL in nonane 1 2 mL
Dicyclohexyl phthalate (unlabeled) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC N N-Dicyclohexyl-2-b 50g
N N-Dicyclohexyl-2-benzothiazolesulfenamide is a compound with reproductive and developmental toxicity that can affect body weight gain reproductive organ weight and multiple reproductive and developmental indicators in rats
Medchemexpress LLC N N-Dicyclohexyl-2-b 5g
N N-Dicyclohexyl-2-benzothiazolesulfenamide is a compound with reproductive and developmental toxicity that can affect body weight gain reproductive organ weight and multiple reproductive and developmental indicators in rats
Medchemexpress LLC Diphenyl disulfide | 882-33-7 | MFCD00003065 | 100.0% | 218.35 g/mol | C12H10S2 | 5g
Diphenyl disulfide is an endogenous metabolite Diphenyl disulfide is a pharmaceutical intermediate Diphenyl disulfide can be coupled with aryl iodide to synthesize asymmetric aryl sulfide[1][2]
![eMolecules Broadpharm / DSPE-SPDP / 50mg / 649282048 / BP-26161 / / 144735-79-5 / [null] / 945.350 / C49H89N2O9PS2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502480332.JPG-250.jpg)
eMolecules Broadpharm / DSPE-SPDP / 50mg / 649282048 / BP-26161 / / 144735-79-5 / [null] / 945.350 / C49H89N2O9PS2
Broadpharm / DSPE-SPDP / 50mg / 649282048 / BP-26161 / / 144735-79-5 / [null] / 945.350 / C49H89N2O9PS2