Sulfoxides
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | 99.5% | C24H28N2O3 | 25 MG
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM).
- Enhances GLP-1 binding to GLP-1R
- Functions as an allosteric modulator
- Acts via a transmembrane site
- Molecular weight: 392.49
- Appearance: solid, white to off-white
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO: 100 mg/mL (254.78 mM)
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | 99.0% | C27H34N6O2 | 25 MG
IL-17 modulator 4 is a proagent of IL-17 modulator 1, an orally active and highly efficacious IL-17 modulator, promising for research into IL-17A mediated diseases like inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome.
- Proagent of an orally active, highly efficacious IL-17 modulator.
- Promising for research into IL-17A mediated diseases.
- Modulates IL-17A protein-protein interaction by stabilizing its conformation and preventing binding to the IL-17RA receptor.
- Inhibits the IL-17A-mediated signaling pathway and IL-8 secretion in HEKa cells (EC50 of 14 nM).
- Exhibits good pharmacokinetic properties in rat models (low clearance, moderate volume of distribution, 3.7 h half-life, 100% oral bioavailability).
- Appearance: solid, off-white to gray.
eMolecules 67-68-5 | Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 1000g | 582637329
Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 1000g | 582637329
Medchemexpress LLC Iduronate 2-sulfatase | 50936-59-9 | >95.0% | 500 UG
Recombinant human iduronate 2-sulfatase (IDS) is a lysosomal enzyme produced in HEK293 cells and supplied lyophilized as an active, His-tagged protein for biochemical and enzymatic studies. It hydrolyzes the C2-sulfate ester of glycosaminoglycans and is provided with validated purity and activity specifications.
- Expressed in HEK293 cells.
- C-terminal 10xHis tag for purification.
- Purity >95.0% by reducing SDS-PAGE.
- Specific activity 6.123 pmoL/min/μg (PNCS substrate assay).
- Lyophilized from 0.22 μm filtered PBS, pH 7.4.
- Approximate molecular weight 75-95 kDa due to glycosylation.
- Store at -20°C; after reconstitution stable at 4°C for 1 week.
- Available in a 500 μg size.
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells
Medchemexpress LLC Mutant p53 modulator-1 | 2746371-35-5 | 99.89% | C27H32F4N8O2 | 100 MG
Mutant p53 modulator-1 is a compound that modulates mutant p53. It has been shown to reduce the progression of various cancers characterized by p53 mutations.
- Functions as a modulator for mutant p53.
- Aids in reducing the progression of cancers with p53 mutations.
- Available in both solid and solution forms for research applications.
Medchemexpress LLC Mutant p53 modulator-1 | 2746371-35-5 | 99.9% | C27H32F4N8O2 | 10MG
Mutant p53 modulator-1 is a small-molecule research reagent reported to modulate mutant p53 and to reduce progression of cancers harboring p53 mutations. It is supplied as a powder for laboratory research and includes stability instructions for storage and handling.
- High purity: 99.9% suitable for analytical and biological studies.
- Defined chemical formula: C27H32F4N8O2 for unambiguous identification.
- Documented stability: powder stable at -20°C for long-term storage.
- Reported activity against mutant p53 to support targeted cancer research.
- Intended for research use only, not for human or clinical use.
eMolecules 142825-10-3 | Medchem Express | (R)-Sulforaphane | 5mg | 599150753 | HY-13755A | MFCD09039283 | 177.28 | C6H11NOS2
Pharmablock | 6-hydroxy-3-methyl-quinazolin-4-one | 100mg | 761042018 | PBCH451 | 19181-69-2 | MFCD20257652 | 176.175 | C9H8N2O2
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Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | 244.33 | 100 MG
Sodium decane-1-sulfonate, also known as 1-Decanesulfonic acid sodium, is an anionic surfactant primarily utilized in analytical chemistry. Its main application lies in the analysis of organic small molecule compounds through High-Performance Liquid Chromatography (HPLC) and ion-pair liquid chromatography. This biochemical assay reagent is a solid with a molecular weight of 244.33 and the chemical formula C10H21NaO3S. It is intended for research use only.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Applications in HPLC and ion-pair liquid chromatography
- Solid form
- Molecular weight: 244.33
- Formula: C10H21NaO3S
- CAS No.: 13419-61-9
- Recommended storage at 4°C, sealed, away from moisture; in solvent: -80°C for 6 months or -20°C for 1 month
- For research use only
eMolecules 4-(Methylsulfinyl)phenol | 14763-64-5 | MFCD00464311 | 1g
Combi-Blocks | 4-(Methylsulfinyl)phenol | 1g | 117542066 | OT-0402 | 98.000 | 14763-64-5 | MFCD00464311 | 156.200 | C7H8O2S
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Medchemexpress LLC Iduronate 2-sulfatase protein, human (HEK293, His) | >95.0% | 50 UG
Recombinant human iduronate 2-sulfatase (IDS) expressed in HEK293 cells and supplied as a C-terminal His-tagged lyophilized protein for research use. The enzyme catalyzes degradation of dermatan sulfate and heparan sulfate and is provided with high purity and defined activity for biochemical assays and protein characterization.
- Supplied as lyophilized powder for convenient storage and transport.
- Expressed in HEK293 for human-like post-translational modifications.
- C-terminal His tag enables affinity purification and detection.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Specific activity reported as 6.123 pmoL/min/μg for functional assays.
- Low endotoxin level (<1 EU/μg) suitable for sensitive applications.
- Stable at -20°C; reconstitute above 100 μg/mL and add carrier protein for long-term storage.
Medchemexpress LLC Sodium butane-1-sulfonate | 2386-54-1 | MFCD00007540 | 98.0% | 160.17 g/mol | C4H9NaO3S | 500 MG
Sodium butane-1-sulfonate is the sodium salt of butane-1-sulfonic acid used as an ionic mobile-phase additive for chromatographic separation of arsenic, selenium, and related analytes. It appears as a white to off-white crystalline powder, supplied for research use, and is commonly used to improve ion-pairing and retention in aqueous chromatographic methods.
- Used as ionic mobile-phase additive for chromatographic separations.
- Improves separation and resolution of arsenic and selenium species.
- High purity suitable for analytical applications (manufacturer lists ~98% assay).
- White to off-white crystalline powder; stable and easy to weigh.
- Suits ion-pairing and retention control in aqueous methods.
Medchemexpress LLC Promethazine sulfoxide | 7640-51-9 | MFCD08063694 | 5mg
Promethazine sulfoxide is a metabolite of the histamine H1 receptor antagonist Promethazine (HY-B1296) It is formed from promethazine by the cytochrome P450 (CYP) isoform CYP2D6
Apexbio Technology LLC Sulindac 38194-50-2 1g
Sulindac (CAS 38194-50-2) is a nonsteroidal anti-inflammatory drug that functions as a prodrug and is metabolized in vivo to pharmacologically active sulindac sulfide and sulindac sulfone Sulindac sulfide acts as a cyclooxygenase inhibitor and modulates intracellular signaling pathways including the repression of ras activity Sulindac sulfone possesses antitumor properties independent of cyclooxygenase inhibition Due to these distinct metabolites and their activities sulindac is utilized in biomedical research for studying inflammatory processes cyclooxygenase-mediated pathways and the chemopreventive mechanisms involved in tumorigenesis