Sulfoxides
Medchemexpress LLC IL-17 modulator 3 | 2467731-88-8 | 99.5% | 579.73 | 25 MG
IL-17 modulator 3 is an IL-17 modulator that can be used for the research of inflammation, cancer, and autoimmune diseases. It is provided as a solid with a purity of 99.51%.
- IL-17 modulator
- Suitable for inflammation research
- Suitable for cancer research
- Suitable for autoimmune diseases research
Medchemexpress LLC Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- | 2097787-75-0 | 99.0% | 308.40 g/mol | C17H16N4S | 10 MG
Nur77 modulator 3 is a small-molecule research compound that binds nuclear receptor Nur77 (NR4A1) and modulates its activity. It has been reported to inhibit TGF-β1-induced α-SMA and COLA1 expression and to reduce hepatic stellate cell activation and extracellular matrix deposition. Technical identifiers include CAS 2097787-75-0, formula C17H16N4S, molecular weight 308.40 g/mol, and purity 99.01%.
- Modulates Nur77 activity in cellular and in vivo models.
- Inhibits TGF-β1-induced α-SMA and COLA1 expression.
- High purity (99.01%) suitable for biochemical and cell-based assays.
- Supplied in small quantities appropriate for assay development and pilot studies.
Medchemexpress LLC Sulindac sulfide | 49627-27-2 | 98.10% | 250 MG
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, demonstrating an IC50 of 20.2 μM for γ42-secretase activity. This compound is primarily used in research, especially for studying neurological diseases.
- Noncompetitive γ-secretase inhibitor
- IC50 of 20.2 μM for γ42-secretase activity
- Suitable for research applications
- Useful for studying neurological diseases
Medchemexpress LLC IL-17A modulator-2 | 2748749-47-3 | 98.4% | C33H31N5O5 | 25 MG
IL-17A modulator-2 is a chemical compound with the molecular formula C33H31N5O5, presented as a white to off-white solid. It has a molecular weight of 577.63 and demonstrates a purity of 98.44% (HPLC). This compound is ideal for research applications requiring a high-purity reagent, with specific storage recommendations to maintain its stability.
- White to off-white solid appearance
- Molecular formula: C33H31N5O5
- Molecular weight: 577.63
- Purity: 98.44% (HPLC)
- Solid form storage: 4°C, sealed, away from moisture and light
- In solvent storage: -80°C for 6 months or -20°C for 1 month, sealed, away from moisture and light
Medchemexpress LLC LRH-1 modulator-1 | 2244781-29-9 | 98.0% | C28H36N2O2S | 10MG
LRH-1 modulator-1 is a research-grade small molecule characterized as a potent agonist/modulator of the liver receptor homolog-1 (LRH-1). The product is provided with analytical documentation and recommended storage and solubility guidance for laboratory and preclinical use.
- Potent LRH-1 modulator/agonist for receptor biology studies.
- High purity (98.0%) suitable for analytical and biological assays.
- Supplied with certificate of analysis, HNMR, and LCMS data for verification.
- Soluble in DMSO; in vivo formulation protocols are provided.
- Stable under specified storage conditions with solvent-specific guidelines.
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | 99.5% | C24H28N2O3 | 25 MG
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM).
- Enhances GLP-1 binding to GLP-1R
- Functions as an allosteric modulator
- Acts via a transmembrane site
- Molecular weight: 392.49
- Appearance: solid, white to off-white
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO: 100 mg/mL (254.78 mM)
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | 99.0% | C27H34N6O2 | 25 MG
IL-17 modulator 4 is a proagent of IL-17 modulator 1, an orally active and highly efficacious IL-17 modulator, promising for research into IL-17A mediated diseases like inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome.
- Proagent of an orally active, highly efficacious IL-17 modulator.
- Promising for research into IL-17A mediated diseases.
- Modulates IL-17A protein-protein interaction by stabilizing its conformation and preventing binding to the IL-17RA receptor.
- Inhibits the IL-17A-mediated signaling pathway and IL-8 secretion in HEKa cells (EC50 of 14 nM).
- Exhibits good pharmacokinetic properties in rat models (low clearance, moderate volume of distribution, 3.7 h half-life, 100% oral bioavailability).
- Appearance: solid, off-white to gray.
Medchemexpress LLC Il-17 modulator 1 disodium | 2446803-91-2 | 98.4% | C28H35N6Na2O6P | 1 ML
IL-17 modulator 1 disodium is an orally active, highly efficacious small molecule IL-17 modulator. Extracted from patent WO 2020127685, this salt form offers enhanced water solubility and stability compared to its free form. It is suitable for research aimed at preventing or ameliorating diseases such as psoriasis, ankylosing spondylitis, and psoriatic arthritis. This product is for research use only.
- Orally active and highly efficacious
- Small molecule IL-17 modulator
- Enhanced water solubility and stability in disodium salt form
- Useful for research into psoriasis, ankylosing spondylitis, and psoriatic arthritis
- White to off-white solid appearance
eMolecules 67-68-5 | Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 220g | 717421096
Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 220g | 717421096
eMolecules 67-68-5 | Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 1000g | 582637329
Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 1000g | 582637329
eMolecules 110-01-0 | Tetrahydrothiophene | Oakwood Chemicals | MFCD00005476 | 88.170 | C4H8S | 98.000 | C1CCSC1 | 1kg | 480116241
Tetrahydrothiophene | Oakwood Chemicals | 110-01-0 | MFCD00005476 | 88.170 | C4H8S | 98.000 | C1CCSC1 | 1kg | 480116241
eMolecules 142825-10-3 | Medchem Express | (R)-Sulforaphane | 5mg | 599150753 | HY-13755A | MFCD09039283 | 177.28 | C6H11NOS2
Pharmablock | 6-hydroxy-3-methyl-quinazolin-4-one | 100mg | 761042018 | PBCH451 | 19181-69-2 | MFCD20257652 | 176.175 | C9H8N2O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | 244.33 | 100 MG
Sodium decane-1-sulfonate, also known as 1-Decanesulfonic acid sodium, is an anionic surfactant primarily utilized in analytical chemistry. Its main application lies in the analysis of organic small molecule compounds through High-Performance Liquid Chromatography (HPLC) and ion-pair liquid chromatography. This biochemical assay reagent is a solid with a molecular weight of 244.33 and the chemical formula C10H21NaO3S. It is intended for research use only.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Applications in HPLC and ion-pair liquid chromatography
- Solid form
- Molecular weight: 244.33
- Formula: C10H21NaO3S
- CAS No.: 13419-61-9
- Recommended storage at 4°C, sealed, away from moisture; in solvent: -80°C for 6 months or -20°C for 1 month
- For research use only
eMolecules 4-(Methylsulfinyl)phenol | 14763-64-5 | MFCD00464311 | 1g
Combi-Blocks | 4-(Methylsulfinyl)phenol | 1g | 117542066 | OT-0402 | 98.000 | 14763-64-5 | MFCD00464311 | 156.200 | C7H8O2S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool