Sulfoxides
Alkali Scientific Novobiocin Sodium Salt, 100 Grams
Novobiocin Sodium Salt is an antibiotic used to inhibit bacterial growth, especially for the isolation of Gram-positive bacteria. This 100g powder formulation is a valuable tool for laboratory research, where it is primarily used to study bacterial resistance mechanisms and to control bacterial contamination in culture media. Novobiocin inhibits DNA gyrase, an essential enzyme in bacterial replication, making it effective for selective bacterial inhibition. Laboratories use this antibiotic for a variety of microbial assays, including testing bacterial susceptibility and studying the biochemical properties of different bacterial strains.
Medchemexpress LLC (R)-Sulforaphane | 142825-10-3 | 99.95% | 177.29 | 5 MG
(R)-Sulforaphane is an orally active and potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. It primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. This compound modulates gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1.
- Can be used in studies of tumor biology, antioxidant defense mechanisms, inflammation, and immune responses
- Promotes transcription of tumor-suppressing proteins
- Effectively inhibits HDAC activity
- Offers cardiac protection by activating the Keap1/Nrf2/ARE pathway and inducing HO-1 expression
- Suppresses high glucose-induced pancreatic cancer via AMPK-dependent signal transmission
- Storage at -20°C, protect from light, stored under nitrogen
- Unstable in solutions, freshly prepared is recommended
Medchemexpress LLC KAT modulator-1 | 1314006-43-3 | C20H36O2 | 5 MG
KAT modulator-1 is a compound identified as a KAT modulator that interacts with p300 full-length, but not its catalytic domain. It is provided as a solid and is intended for laboratory chemicals, manufacture of substances, and epigenetics research, including drug screening applications.
- Targets histone acetyltransferase
- Used in cancer research
- Interacts with p300 full-length
- Suitable for epigenetics research
- Identified for laboratory use and drug screening
- Provided as a solid
- For research use only
Medchemexpress LLC Sirtuin modulator 2 | 667910-69-2 | 99.2% | 349.41 | 25 MG
Sirtuin modulator 2 (Compound 132) is a sirtuin modulator exhibiting an ED50 equal to or less than 50 μM. It is intended for research use only. This compound is characterized by its molecular weight of 349.41 and appears as a light yellow to yellow solid.
- Appears as a light yellow to yellow solid.
- Has an ED50 equal to or less than 50 μM.
- Intended for research applications.
eMolecules 67-68-5 | Dimethyl Sulfoxide | AA Blocks LLC | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 250g | 784389378
Dimethyl Sulfoxide | AA Blocks LLC | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 250g | 784389378
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 1 ML
CB2R/FAAH modulator-3 is a dual-targeting modulator that functions as a Cannabinoid receptor 2 (CB2R) agonist and a Fatty Acid Amide Hydrolase (FAAH) inhibitor. This modulator demonstrates a high affinity for CB2R with a Ki value of 20.1 nM, and a lower affinity for CB1R with a Ki value of 67.6 nM. It inhibits FAAH with an IC50 value of 3.4 μM. In in vitro studies, at a concentration of 10 μM, it has been shown to reduce the production of pro-inflammatory cytokines, including TNFα, IFN-γ, IL-1β, and IL6, in unstimulated monocytes and macrophages.
- Suitable for use in research related to various conditions, such as cancer.
- Suitable for use in research related to inflammatory cascades associated with neurodegenerative diseases.
- Suitable for use in research related to COVID-19 infection.
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 5 MG
CB2R/FAAH modulator-3 (compound 27) is a dual-targeting modulator that acts as a CB2R agonist and FAAH inhibitor. It has Ki values of 20.1 nM for CB2R and 67.6 nM for CB1R, and an IC50 value of 3.4 μM for FAAH. This compound can be used in studies related to cancer, deleterious inflammatory cascades in neurodegenerative diseases, and COVID-19 infection.
- Dual-targeting modulator: acts as a CB2R agonist and FAAH inhibitor.
- Can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
- At 10 μM, it reduces the production of the pro-inflammatory cytokines TNFα, IFN-γ, IL-1β, and IL6 in unstimulated monocytes and macrophages.