Sulfoxides
Cayman Chemical Sulindac Inhibitors
An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide; selective for COX-2 over COX-1 (IC50 = >1,000 µM); inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema in rats at 100 mg/kg; reduces tumor growth in a BxPC-3 mouse xenograft model at 60 mg/kg
Medchemexpress LLC Sulforaphane | 4478-93-7 | MFCD00198068 | 98.9% | 177.29 g/mol | C6H11NOS2 | 5 MG
Sulforaphane is a research-grade isothiocyanate that activates the Keap1/Nrf2/ARE antioxidant pathway and inhibits histone deacetylases. Supplied as a high-purity powder, it is intended for use in in vitro and in vivo studies of antioxidant response, anticancer activity, and anti-inflammatory mechanisms.
- High purity: 98.9%.
- CAS number: 4478-93-7.
- Molecular formula: C6H11NOS2; MW: 177.29 g/mol.
- Suitable for in vitro and in vivo applications.
- Storage: powder -20°C; in solvent -80°C for long-term storage.
- Available in small research quantities, including 5 mg.
Medchemexpress LLC Sulforaphane | 4478-93-7 | 99.75% | 177.29 | 200 MG
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. It promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. It protects the heart through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission and exhibits both anticancer and anti-inflammatory properties.
- Targets: HDAC, Keap1-Nrf2, Apoptosis, Bcl-2 family, Caspase, Reactive oxygen species (ROS)
- Research areas: Inflammation/Immunology, Cancer
Aobchem Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 250mg
Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 250mg
Medchemexpress LLC 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1-(2-phenylethyl)- | 421578-93-0 | 99.81% | C24H21NO3 | 1 ML
GLP-1R modulator C5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM). This compound is for research use only.
- Allosteric modulator
- Enhances GLP-1 binding to GLP-1R
- Via a transmembrane site
Aobchem (4-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 70398-89-9 | C9H11BrS | 1g
(4-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 70398-89-9 | C9H11BrS | 1g
Aobchem (4-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 70398-89-9 | C9H11BrS | 5g
(4-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 70398-89-9 | C9H11BrS | 5g
Aobchem Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 1g
Allyl(3 5-dimethoxyphenyl)sulfane | 97% | C11H14O2S | 1g
Aobchem (3-Isobutylphenyl)(methyl)sulfane | 95% | C11H16S | 500mg
(3-Isobutylphenyl)(methyl)sulfane | 95% | C11H16S | 500mg
Medchemexpress LLC Mrgprx2 modulator-1 (example 17) | 2781839-42-5 | 99.0% | 459.39 g/mol | C20H19F6N5O | 10 MG
MRGPRX2 modulator-1 (example 17) is a small-molecule modulator of the Mas-related G-protein coupled receptor X2 (MRGPRX2) supplied for preclinical research. It is intended for studies of inflammation, pain signaling, and autoimmune disorders and is characterized by a confirmed molecular formula, molecular weight, and high HPLC purity.
- Small-molecule modulator of MRGPRX2 suitable for preclinical research.
- High purity (99.03% by HPLC) for consistent bioactivity.
- Molecular formula: C20H19F6N5O; molecular weight: 459.39 g/mol.
- Assigned CAS number 2781839-42-5 for unambiguous identification.
- Provided as a powdered research reagent; handle per SDS instructions.
Aobchem (2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 500mg
(2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 500mg
Aobchem (2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 1g
(2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 1g
Sigma Aldrich Fine Chemicals Biosciences 1,2-Bis(phenylsulfinyl)ethane palladium(II) acetate | 858971-43-4 | MFCD09842752 | 250MG
1,2-Bis(phenylsulfinyl)ethane palladium(II) acetate | Mol Wt: 502.9 | 858971-43-4 | MFCD09842752 | 250MG
