Thioureas
AdipoGen 7-OH-4-methyl-21H-quinolone
Chemical. CAS 20513-71-7. Formula C10H9NO2. MW 175.18. Synthetic. 7-Hydroxy-4-methyl-21H-quinolone is a starting material for the synthesis of a potential cytotoxic compound class with activity against human tumor cell lines.
AdipoGen 7b-OH-cholesteryl-bishemisucci
Chemical. CAS 105449-93-2. Formula C35H54O8 . 2C2H7NO. MW 602.80 . 61.08. Synthetic Water-soluble derivatives of 7beta-hydroxycholesterol. Anticancer compound, inducing apoptosis in various solid tumor cell lines.
AdipoGen 7b-OH-cholesteryl-bishemisucci
Chemical. CAS 105449-93-2. Formula C35H54O8 . 2C2H7NO. MW 602.80 . 61.08. Synthetic Water-soluble derivatives of 7beta-hydroxycholesterol. Anticancer compound, inducing apoptosis in various solid tumor cell lines.
AdipoGen 1 5-Isoquinolinediol
Chemical. CAS 5154-02-9. Formula C9H7NO2. MW 161.2. PARP-1 inhibitor. Neuroprotectant. Blocks nitric oxide-induced neuronal toxicity. Potent iNOS inducible nitric oxide synthase/NOS II inhibitor. Stimulates homologous recombination.
Indofine Chemical THIOUREA, Products for Life Science, 62-56-6, 1 kg
THIOUREA, Products for Life Science, 62-56-6, 1 kg
AdipoGen 1 5-Isoquinolinediol
Chemical. CAS 5154-02-9. Formula C9H7NO2. MW 161.2. PARP-1 inhibitor. Neuroprotectant. Blocks nitric oxide-induced neuronal toxicity. Potent iNOS inducible nitric oxide synthase/NOS II inhibitor. Stimulates homologous recombination.
Chem-Impex International, Inc. Thiourea | 62-56-6 | MFCD00008067 | 1KG
Thiourea, 62-56-6, MFCD00008067, 1KG
eMolecules 105-55-5 | 1,3-Diethyl-2-thiourea | Oakwood Chemicals | MFCD00004925 | 132.230 | C5H12N2S | 0.000 | CCNC(=S)NCC | 25g | 480149343
1,3-Diethyl-2-thiourea | Oakwood Chemicals | 105-55-5 | MFCD00004925 | 132.230 | C5H12N2S | 0.000 | CCNC(=S)NCC | 25g | 480149343
AdipoGen Carboplatin
Chemical. CAS 41575-94-4. Formula C6H12N2O4Pt. MW 371.3. Potent platinum-based antineoplastic agent. Analog of cisplatin Prod. No. AG-CR1-3590 with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage.
AdipoGen Suc-Leu-Leu-Val-Tyr-AMC
Chemical. CAS 94367-21-2. Formula C40H53N5O10. MW 763.9. Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases. Extinction 380nm. Emission 460 nm. This substrate is useful for inhibitor screening and kinetic analysis.
AdipoGen Suc-Leu-Leu-Val-Tyr-AMC
Chemical. CAS 94367-21-2. Formula C40H53N5O10. MW 763.9. Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases. Extinction 380nm. Emission 460 nm. This substrate is useful for inhibitor screening and kinetic analysis.
AdipoGen Q-VD-OPh
Chemical. CAS 1135695-98-5 anhydrous. Formula C26H25F2N3O6. MW 513.5. Synthetic. Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl OPh group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies.
AdipoGen L-Alanyl-L-glutamine
Chemical. CAS 39537-23-0. Formula C8H15N3O4. MW 217.22. Synthetic. L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine Ala-Gln and Gylcyl-L-glutamine Gly-Gln are used in cell culture media as alternative delivery forms of stabilized L-glutamine. Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals, cosmetics and food products. Alanyl-glutamine also acts as an antioxidant peroxide and anti-apoptosis LPS-induced factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro. Shown to improve intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy.
AdipoGen Z-Phe-Arg-AFC
Chemical. CAS 93753-73-2 free base. Formula C33H33F3N6O6 . C2HF3O2. MW 666.7 . 114.0. Synthetic. Fluorogenic substrate, specifically used to determine the enzyme activity of Cathepsin L. Useful for the study of cathepsin activity and for screening small molecule inhibitors for drug discovery and HTS applications. Likely to be cleaved by cathepsins B, F, K, S and L, cathepsins L-like proteases and proteases such as papain, cruzipain, plasma kallikrein, soybean trypsin-like enzyme and the falcipains-1 and -2 malaria hemoglobinases. Hydrolysis of this substrate is monitored by observing fluorescence at an Excitation of 400nm and Emission at 505nm.
Biomatik Corporation Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7
Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7