Thioureas
Biomatik Corporation Pepstatin A. Grade High Purity. Storage 4C. CAS 8913806
Pepstatin A. Grade High Purity. Storage 4C. CAS 8913806
eMolecules Thiourea-13C | 113899-66-4 | MFCD00084092 | 500mg
Toronto Research Chemicals | Thiourea-13C | 500mg | 601600936 | T375454 | | 113899-66-4 | MFCD00084092 | 77.110 | CH4N2S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Biomatik Corporation Puromycin, Dihydrochloride. Grade Biotechnology. Storage -20C. CAS 58-58-2
Puromycin, Dihydrochloride. Grade Biotechnology. Storage -20C. CAS 58-58-2
eMolecules 6-Phenyl-2-thioxo-2,3-dihydropyrimidin-4(1h)-one | 36822-11-4 | MFCD00465574 | 1g
Combi-Blocks, Inc. | 6-Phenyl-2-thioxo-2,3-dihydropyrimidin-4(1h)-one | 1g | 569293854 | QZ-6033 | 95.000 | 36822-11-4 | MFCD00465574 | 204.250 | C10H8N2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules 5,6-Dimethyl-2-thiouracil | 28456-54-4 | MFCD00278872 | 25g
Combi-Blocks | 5,6-Dimethyl-2-thiouracil | 25g | 401038904 | QJ-2954 | 97.000 | 28456-54-4 | MFCD00278872 | 156.200 | C6H8N2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules Oakwood Chemicals Thiourea ACS Reagent Grade 25g 480154135 103320 62-56-6 MFCD00008067 76.120 CH4N2S
Oakwood Chemicals Thiourea ACS Reagent Grade 25g 480154135 103320 62-56-6 MFCD00008067 76.120 CH4N2S
AdipoGen Zoxamide
Chemical. CAS 156052-68-5. Formula C14H16Cl3NO2. MW 336.6. Synthetic. Fungicide. Primarily an oomycete fungicide although it has some activity against ascomycetes and basidiomycetes. The product acts by disruption of the microtubule structure and inhibition of cell division. The mechanism for this activity is through the covalent binding of the active ingredient to beta-tubulin in the cytoskeleton. Scanning microscopy studies showed zoxamide action against blight on potato crops begins after germination, achieving inhibition of hyphal development and sporangia production. This novel mode of action makes zoxamide an important new tool in antiresistance strategies. Can be used as a reference compound.
AdipoGen Zoxamide
Chemical. CAS 156052-68-5. Formula C14H16Cl3NO2. MW 336.6. Synthetic. Fungicide. Primarily an oomycete fungicide although it has some activity against ascomycetes and basidiomycetes. The product acts by disruption of the microtubule structure and inhibition of cell division. The mechanism for this activity is through the covalent binding of the active ingredient to beta-tubulin in the cytoskeleton. Scanning microscopy studies showed zoxamide action against blight on potato crops begins after germination, achieving inhibition of hyphal development and sporangia production. This novel mode of action makes zoxamide an important new tool in antiresistance strategies. Can be used as a reference compound.
eMolecules 2-Mercapto-6-phenylpyrimidin-4(3h)-one | 36822-11-4 | MFCD00847526 | 1g
Combi-Blocks, Inc. | 2-Mercapto-6-phenylpyrimidin-4(3h)-one | 1g | 569293205 | QK-4183 | 95.000 | 36822-11-4 | MFCD00847526 | 204.250 | C10H8N2OS
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules Chem-Impex Thiourea 100kg 112439619 00284 0 000 62-56-6 MFCD00008067 76 120 CH4N2S
Chem-Impex Thiourea 100kg 112439619 00284 0 000 62-56-6 MFCD00008067 76 120 CH4N2S
AdipoGen Z-Phe-Arg-AFC
Chemical. CAS 93753-73-2 free base. Formula C33H33F3N6O6 . C2HF3O2. MW 666.7 . 114.0. Synthetic. Fluorogenic substrate, specifically used to determine the enzyme activity of Cathepsin L. Useful for the study of cathepsin activity and for screening small molecule inhibitors for drug discovery and HTS applications. Likely to be cleaved by cathepsins B, F, K, S and L, cathepsins L-like proteases and proteases such as papain, cruzipain, plasma kallikrein, soybean trypsin-like enzyme and the falcipains-1 and -2 malaria hemoglobinases. Hydrolysis of this substrate is monitored by observing fluorescence at an Excitation of 400nm and Emission at 505nm.
AdipoGen Ixazomib MLN2238
Chemical. CAS 1072833-77-2. Formula C14H19BCl2N2O4. MW 361. Synthetic. Potent selective and reversible proteasome inhibitor all proteolytic subunits. Targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome IC50=3.4nM. Cross-reacts and inhibits the trypsin-like beta2 subunit IC50=3.5µM and the caspase-like/peptidyl-glutamyl peptide-hydrolyzing PGPH beta1 subunit IC50=0.03µM. Anticancer compound effective in cell-based assays, in xenografts and against multiple myeloma in vivo. In vitro, induces cell cycle arrest and apoptosis in human cancer cell lines including multiple myeloma. Biologically active form of the prodrug MLN9708 AG-CR1-3671. Exhibits improved pharmacodynamics and antitumor activity compared to bortezomib in various B-cell lymphoma models, due to a greater tumor to blood ratio of proteasome inhibition that ultimately translates into improved tumor pharmacodynamic response and antitumor activity in several tumor xenograft models.
AdipoGen Colcemid
Chemical. CAS 477-30-5. Formula C21H25NO5. MW 371.4. Semisynthetic from colchicine Prod. No. AG-CN2-0048. Anti-cancer compound. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation inactivates spindle fibre formation. Inhibits mitosis during cell division at metaphase by inhibiting spindle formation. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center. Apoptosis inducer. Thrombopoietic agent.
AdipoGen Suc-Leu-Leu-Val-Tyr-AMC
Chemical. CAS 94367-21-2. Formula C40H53N5O10. MW 763.9. Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases. Extinction 380nm. Emission 460 nm. This substrate is useful for inhibitor screening and kinetic analysis.
AdipoGen PJ-34
Chemical. CAS 344458-15-7. Formula C17H17N3O2 . HCl. MW 295.2 . 36.5. Potent, water soluble polyADP-ribose polymerase PARP inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells.